Inter-Site Cooperativity of Calmodulin N-Terminal Domain and Phosphorylation Synergistically Improve the Affinity and Selectivity for Uranyl

Autor: Maria Rosa Beccia, Sandrine Sauge-Merle, Nicolas Brémond, David Lemaire, Pierre Henri, Christine Battesti, Philippe Guilbaud, Serge Crouzy, Catherine Berthomieu

Publikováno v: Biomolecules, Vol 12, Iss 11, p 1703 (2022)

Uranyl–protein interactions participate in uranyl trafficking or toxicity to cells. In addition to their qualitative identification, thermodynamic data are needed to predict predominant mechanisms that they mediate in vivo. We previously showed tha

Externí odkaz: https://doaj.org/article/b00ced0c32114e55a3fa4838f0f0d24a

hW-inference: A heuristic approach to retrieve models through black box testing

Autor: Nicolas Brémond, Catherine Oriat, Roland Groz, Adenilso Simao

Publikováno v: Journal of Systems and Software
Journal of Systems and Software, Elsevier, 2020, 159, pp.110426. ⟨10.1016/j.jss.2019.110426⟩
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

We present an efficient approach to retrieve behavioural models from reactive software systems in the form of Finite State Machines by testing them. The system is accessed in black box mode; thus, no source or binary code is needed. The novelty of th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94f5ad6a479e862b80420744ca246d3b
https://hal.archives-ouvertes.fr/hal-03275239

Case Studies in Learning Models and Testing Without Reset

Autor: Roland Groz, Nicolas Brémond

Publikováno v: 2019 IEEE International Conference on Software Testing, Verification and Validation Workshops (ICSTW: AMOST 2019)
2019 IEEE International Conference on Software Testing, Verification and Validation Workshops (ICSTW: AMOST 2019), Apr 2019, Xi'an, China. pp.40-45, ⟨10.1109/ICSTW.2019.00030⟩
ICST Workshops

This paper assesses a method to reverse engineer models from software or cyber-physical systems that cannot be reset. This is done through active learning, and can compare favourably as a systematic testing method.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad330f3b295a2c11d9d1ca3afef4038b
https://hal.archives-ouvertes.fr/hal-03275229

Development of an Efficient FRET-Based Ratiometric Uranium Biosensor

Autor: Sandrine Sauge-Merle, Morgane Recuerda, Maria Rosa Beccia, David Lemaire, Rym Cherif, Nicolas Bremond, Fabienne Merola, Yasmina Bousmah, Catherine Berthomieu

Publikováno v: Biosensors, Vol 13, Iss 5, p 561 (2023)

The dispersion of uranium in the environment can pose a problem for the health of humans and other living organisms. It is therefore important to monitor the bioavailable and hence toxic fraction of uranium in the environment, but no efficient measur

Externí odkaz: https://doaj.org/article/021500a37e524f309b96e1e49e9fa391

Lineage Tracking for Probing Heritable Phenotypes at Single-Cell Resolution.

Autor: Denis Cottinet, Florence Condamine, Nicolas Bremond, Andrew D Griffiths, Paul B Rainey, J Arjan G M de Visser, Jean Baudry, Jérôme Bibette

Publikováno v: PLoS ONE, Vol 11, Iss 4, p e0152395 (2016)

Determining the phenotype and genotype of single cells is central to understand microbial evolution. DNA sequencing technologies allow the detection of mutants at high resolution, but similar approaches for phenotypic analyses are still lacking. We s

Externí odkaz: https://doaj.org/article/6332a03f34ec4c6fa0ba5c08143c43d9