Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicolas Bellini"'
Autor:
Nicolas Bellini, Chengyu Ye, Oluwaseun Ajibola, Thomas T. Murooka, Robert Lodge, Éric A. Cohen
Publikováno v:
Viruses, Vol 16, Iss 7, p 1076 (2024)
MicroRNAs (miRNAs) play important roles in the control of HIV-1 infection. Here, we performed RNA-seq profiling of miRNAs and mRNAs expressed in CD4+ T lymphocytes upon HIV-1 infection. Our results reveal significant alterations in miRNA and mRNA exp
Externí odkaz:
https://doaj.org/article/98ea85c54eba4a34b070bb0e76291d42
Autor:
Nicolas Bellini, Robert Lodge, Tram N.Q. Pham, Jaspreet Jain, Thomas T. Murooka, Alon Herschhorn, Nicole F. Bernard, Jean-Pierre Routy, Cécile L. Tremblay, Éric A. Cohen
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105234- (2022)
Summary: Activated-to-memory transitioning CD4+ T cells display elevated expression of the HIV-1 co-receptor CCR5 and are more prone to HIV-1 latent infection. Here, we show that p53-regulated miRNA-103 downmodulates CCR5 levels in CD4+ T lymphocytes
Externí odkaz:
https://doaj.org/article/30d4e7980f46475a9a5b3a72a2a0365d
Autor:
Robert Lodge, Nicolas Bellini, Mélanie Laporte, Syim Salahuddin, Jean-Pierre Routy, Petronela Ancuta, Cecilia T. Costiniuk, Mohammad-Ali Jenabian, Éric A. Cohen
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Macrophages are a target of human immunodeficiency virus type 1 (HIV-1) and may serve as a viral reservoir during antiretroviral therapy (ART). Their susceptibility to HIV-1 infection is subject to variations from permissiveness to resistanc
Externí odkaz:
https://doaj.org/article/bf3c9c672de24376b80f6cc1733e60a9
Autor:
Olivia Blake, Denys Brand, Nicolas Bellini, Emmanuelle Roch, Fabrizio Mammano, Alain Moreau, Martine Braibant, Julie Migraine, Jean-Christophe Plantier, Mélanie Bouvin-Pley, Marie Leoz
Publikováno v:
AIDS
AIDS, Lippincott, Williams & Wilkins, 2020, 34 (15), pp.2187-2200. ⟨10.1097/qad.0000000000002690⟩
AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2020, 34 (15), pp.2187-2200. ⟨10.1097/qad.0000000000002690⟩
AIDS, Lippincott, Williams & Wilkins, 2020, 34 (15), pp.2187-2200. ⟨10.1097/qad.0000000000002690⟩
AIDS. Official journal of the international AIDS Society
AIDS. Official journal of the international AIDS Society, 2020, 34 (15), pp.2187-2200. ⟨10.1097/qad.0000000000002690⟩
International audience; Objective: HIV-1 transmission leads to a genetic bottleneck, with one or a few variants of the donor quasispecies establishing an infection in the new host. We aimed to characterize this bottleneck in more detail, by comparing
Autor:
Mohammad-Ali Jenabian, Éric A. Cohen, Melanie Laporte, Robert Lodge, Syim Salahuddin, Petronela Ancuta, Jean-Pierre Routy, Nicolas Bellini, Cecilia T. Costiniuk
Publikováno v:
mBio
mBio, Vol 11, Iss 5 (2020)
mBio, Vol 11, Iss 5 (2020)
Macrophages are heterogeneous immune cells that display varying susceptibilities to HIV-1 infection, in part due to the expression of small noncoding microRNAs involved in the posttranscriptional regulation of gene expression and silencing. Here, we