Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Nicolas Agier"'
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0297014 (2024)
Recent advances in long-read sequencing technologies have enabled the complete assembly of eukaryotic genomes from telomere to telomere by allowing repeated regions to be fully sequenced and assembled, thus filling the gaps left by previous short-rea
Externí odkaz:
https://doaj.org/article/1fdcfdebc6d94929baed32cbc98398c3
Autor:
Pablo Villarreal, Samuel O'Donnell, Nicolas Agier, Felipe Muñoz-Guzman, Jose Benavides-Parra, Kami Urbina, Tomas A. Peña, Mark Solomon, Roberto F. Nespolo, Gilles Fischer, Cristian Varela, Francisco A. Cubillos
Publikováno v:
mSystems, Vol 9, Iss 1 (2024)
ABSTRACTEvaluating domestication signatures beyond model organisms is essential for a thorough understanding of the genotype-phenotype relationship in wild and human-related environments. Structural variations (SVs) can significantly impact phenotype
Externí odkaz:
https://doaj.org/article/5d0e55c2cb304d0ca70fbbb52bba6c72
Autor:
Rossana Droghetti, Nicolas Agier, Gilles Fischer, Marco Gherardi, Marco Cosentino Lagomarsino
Publikováno v:
eLife, Vol 10 (2021)
Recent results comparing the temporal program of genome replication of yeast species belonging to the Lachancea clade support the scenario that the evolution of the replication timing program could be mainly driven by correlated acquisition and loss
Externí odkaz:
https://doaj.org/article/b85398afda6848d58207bec082e4d85b
Autor:
Nicolas Agier, Stéphane Delmas, Qing Zhang, Aubin Fleiss, Yan Jaszczyszyn, Erwin van Dijk, Claude Thermes, Martin Weigt, Marco Cosentino-Lagomarsino, Gilles Fischer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Temporal programs of genome replication show different levels of conservation between closely or distantly related species. Here, the authors generate genome-wide replication timing profiles for ten yeast species, and analyze their evolutionary dynam
Externí odkaz:
https://doaj.org/article/f394fafe14464009957b771ab49d4e78
Autor:
Aubin Fleiss, Samuel O'Donnell, Téo Fournier, Wenqing Lu, Nicolas Agier, Stéphane Delmas, Joseph Schacherer, Gilles Fischer
Publikováno v:
PLoS Genetics, Vol 15, Iss 8, p e1008332 (2019)
Genome engineering is a powerful approach to study how chromosomal architecture impacts phenotypes. However, quantifying the fitness impact of translocations independently from the confounding effect of base substitutions has so far remained challeng
Externí odkaz:
https://doaj.org/article/26b5802e9fd0491c954331f99f9a0b68
Autor:
Céline Tomkiewicz, Stéphane Hans, Marie Hélène Mucchielli, Nicolas Agier, Hervé Delacroix, Laetitia Marisa, Daniel Brasnu, Lawrence P Aggerbeck, Cécile Badoual, Robert Barouki, Martine Aggerbeck
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e47170 (2012)
BACKGROUND: It is a major clinical challenge to predict which patients, with advanced stage head and neck squamous cell carcinoma, will not exhibit a reduction in tumor size following induction chemotherapy in order to avoid toxic effects of ineffect
Externí odkaz:
https://doaj.org/article/5508f337638946219925281b12662696
Autor:
Nicolas Maunoury, Miguel Redondo-Nieto, Marie Bourcy, Willem Van de Velde, Benoit Alunni, Philippe Laporte, Patricia Durand, Nicolas Agier, Laetitia Marisa, Danièle Vaubert, Hervé Delacroix, Gérard Duc, Pascal Ratet, Lawrence Aggerbeck, Eva Kondorosi, Peter Mergaert
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9519 (2010)
The legume plant Medicago truncatula establishes a symbiosis with the nitrogen-fixing bacterium Sinorhizobium meliloti which takes place in root nodules. The formation of nodules employs a complex developmental program involving organogenesis, specif
Externí odkaz:
https://doaj.org/article/871e1b721147415fb7f6ad5ad9b3eee4
Autor:
Frank Johannes, Emmanuelle Porcher, Felipe K Teixeira, Vera Saliba-Colombani, Matthieu Simon, Nicolas Agier, Agnès Bulski, Juliette Albuisson, Fabiana Heredia, Pascal Audigier, David Bouchez, Christine Dillmann, Philippe Guerche, Frédéric Hospital, Vincent Colot
Publikováno v:
PLoS Genetics, Vol 5, Iss 6, p e1000530 (2009)
Loss or gain of DNA methylation can affect gene expression and is sometimes transmitted across generations. Such epigenetic alterations are thus a possible source of heritable phenotypic variation in the absence of DNA sequence change. However, attem
Externí odkaz:
https://doaj.org/article/bafad8a6e27b4b59b4d9ffd954dd9a25
Autor:
Matthew W Vaughn, Milos Tanurdzić, Zachary Lippman, Hongmei Jiang, Robert Carrasquillo, Pablo D Rabinowicz, Neilay Dedhia, W Richard McCombie, Nicolas Agier, Agnès Bulski, Vincent Colot, R W Doerge, Robert A Martienssen
Publikováno v:
PLoS Biology, Vol 5, Iss 7, p e174 (2007)
Cytosine methylation of repetitive sequences is widespread in plant genomes, occurring in both symmetric (CpG and CpNpG) as well as asymmetric sequence contexts. We used the methylation-dependent restriction enzyme McrBC to profile methylated DNA usi
Externí odkaz:
https://doaj.org/article/dd8d3263f2654a5dbd3afc8a14c3c819
Autor:
Pablo Villarreal, Carlos A. Villarroel, Sam O'Donnell, Nicolas Agier, Julian F. Quintero‐Galvis, Tomas A. Peña, Roberto F. Nespolo, Gilles Fischer, Cristian Varela, Francisco A. Cubillos
Publikováno v:
Environmental Microbiology. 24:5615-5629
Most organisms belonging to the Saccharomycotina subphylum have high genetic diversity and a vast repertoire of metabolisms and lifestyles. Lachancea cidri is an ideal yeast model for exploring the interplay between genetics, ecological function and