Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nicolas A. Morrice"'
Autor:
Michael F. Olson, Mairi Sime, Alexander W. Schüttelkopf, Nicola Rath, Gregory Naylor, June Munro, Nicolas A. Morrice, Mokdad Mezna, Carol McMenemy, Heather McKinnon, Lynn McGarry, Laura McDonald, Patricia McConnell, Duncan McArthur, Sergio Lilla, Jennifer Konczal, James A.M. Hall, David A. Greenhalgh, Christopher Gray, Kathryn Gill, Mathew J. Garnett, Martin J. Drysdale, Daniel R. Croft, Diane Crighton, Jacqueline Cordes, Maeve Clarke, Justin Bower, Simone Belshaw, Mathieu Unbekandt
Supplemental Figure 1. Kinome selectivity profiles for BDP8900 and BDP9066. Supplemental Figure 2. Cancer cell line sensitivity to BDP8900 and BDP9066. Supplemental Figure 3. MRCKα phosphorylations compared with MRCKβ. Supplemental Figure 4. MRCKα
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::346ca491ecd7dc79d9211d65d7730216
https://doi.org/10.1158/0008-5472.22420712.v1
https://doi.org/10.1158/0008-5472.22420712.v1
Autor:
Michael F. Olson, Mairi Sime, Alexander W. Schüttelkopf, Nicola Rath, Gregory Naylor, June Munro, Nicolas A. Morrice, Mokdad Mezna, Carol McMenemy, Heather McKinnon, Lynn McGarry, Laura McDonald, Patricia McConnell, Duncan McArthur, Sergio Lilla, Jennifer Konczal, James A.M. Hall, David A. Greenhalgh, Christopher Gray, Kathryn Gill, Mathew J. Garnett, Martin J. Drysdale, Daniel R. Croft, Diane Crighton, Jacqueline Cordes, Maeve Clarke, Justin Bower, Simone Belshaw, Mathieu Unbekandt
The myotonic dystrophy–related Cdc42-binding kinases MRCKα and MRCKβ contribute to the regulation of actin–myosin cytoskeleton organization and dynamics, acting in concert with the Rho-associated coiled-coil kinases ROCK1 and ROCK2. The absence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af16f4361b0ccac85ceb818cb8359866
https://doi.org/10.1158/0008-5472.c.6510734
https://doi.org/10.1158/0008-5472.c.6510734
Autor:
Michael F. Olson, Nicolas A. Morrice, Stephan M. Feller, June Munro, Mathew L. Coleman, Suzanne C. Brady
Supplementary Table 1 from Sprouty2 Association with B-Raf Is Regulated by Phosphorylation and Kinase Conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1be41d7bbc695e73b8d6a97df9a4ad57
https://doi.org/10.1158/0008-5472.22377510.v1
https://doi.org/10.1158/0008-5472.22377510.v1
Autor:
Michael F. Olson, Nicolas A. Morrice, Stephan M. Feller, June Munro, Mathew L. Coleman, Suzanne C. Brady
Supplementary Figure 1 from Sprouty2 Association with B-Raf Is Regulated by Phosphorylation and Kinase Conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3650f3e8d49c93956ede07d2699fd1d2
https://doi.org/10.1158/0008-5472.22377525
https://doi.org/10.1158/0008-5472.22377525
Autor:
Michael F. Olson, Nicolas A. Morrice, Stephan M. Feller, June Munro, Mathew L. Coleman, Suzanne C. Brady
Supplementary Figure 3 from Sprouty2 Association with B-Raf Is Regulated by Phosphorylation and Kinase Conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::740c9ff40a519b47c73b9ee542e7a85f
https://doi.org/10.1158/0008-5472.22377519.v1
https://doi.org/10.1158/0008-5472.22377519.v1
Autor:
Michael F. Olson, Nicolas A. Morrice, Stephan M. Feller, June Munro, Mathew L. Coleman, Suzanne C. Brady
Supplementary Figure 4 from Sprouty2 Association with B-Raf Is Regulated by Phosphorylation and Kinase Conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c26152a6431b70d7e2a4312b23e2e4c
https://doi.org/10.1158/0008-5472.22377516.v1
https://doi.org/10.1158/0008-5472.22377516.v1
Autor:
Michael F. Olson, Nicolas A. Morrice, Stephan M. Feller, June Munro, Mathew L. Coleman, Suzanne C. Brady
Supplementary Methods, Legends for Figures 1-4 from Sprouty2 Association with B-Raf Is Regulated by Phosphorylation and Kinase Conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0d56b1f225c0f44a4e78d7e550e3d98
https://doi.org/10.1158/0008-5472.22377513
https://doi.org/10.1158/0008-5472.22377513
Autor:
Michael F. Olson, Nicolas A. Morrice, Stephan M. Feller, June Munro, Mathew L. Coleman, Suzanne C. Brady
Supplementary Figure 2 from Sprouty2 Association with B-Raf Is Regulated by Phosphorylation and Kinase Conformation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bcb1587b21d64092891ed63eef0a6ab
https://doi.org/10.1158/0008-5472.22377522
https://doi.org/10.1158/0008-5472.22377522
Autor:
Michael F. Olson, June Munro, Stephan M. Feller, Nicolas A. Morrice, Mathew L. Coleman, Suzanne C. Brady
Publikováno v:
Cancer research. 69(17)
Sprouty2 is a feedback regulator that controls the Ras/Raf/MEK/extracellular signal-regulated kinase mitogen-activated protein kinase (MAPK) pathway at multiple levels, one way being through direct interaction with Raf kinases. Consistent with a role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3aead0209478158a3c2c4affe44f1d2
https://pubmed.ncbi.nlm.nih.gov/19690147
https://pubmed.ncbi.nlm.nih.gov/19690147
Autor:
Selva B. Cigorraga, Nicolas A. Morrice, David A. Pan, Kei Sakamoto, D. Grahame Hardie, Alan Ashworth, Mhairi C. Towler, Silvina Beatriz Meroni, Simon A. Hawley, David M. A. Martin, Afshan McCarthy, Sarah Fogarty, Maria Noel Lujan Galardo
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2008, 416 (1), pp.1-14. ⟨10.1042/BJ20081447⟩
Biochemical Journal, Portland Press, 2008, 416 (1), pp.1-14. ⟨10.1042/BJ20081447⟩
International audience; LKB1 was discovered as a tumour suppressor mutated in Peutz-Jeghers syndrome and a gene involved in cell polarity, and is an upstream protein kinase for members of the AMP-activated protein kinase family. We report that mammal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e8558c5551de4b3fb35db9fa2891850
https://hal.archives-ouvertes.fr/hal-00479070
https://hal.archives-ouvertes.fr/hal-00479070