Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicolas A Gort-Freitas"'
Autor:
Claire D McWhite, Wisath Sae-Lee, Yaning Yuan, Anna L Mallam, Nicolas A Gort-Freitas, Silvia Ramundo, Masayuki Onishi, Edward M Marcotte
Publikováno v:
Molecular Systems Biology, Vol 20, Iss 8, Pp 933-951 (2024)
Abstract The variability of proteins at the sequence level creates an enormous potential for proteome complexity. Exploring the depths and limits of this complexity is an ongoing goal in biology. Here, we systematically survey human and plant high-th
Externí odkaz:
https://doaj.org/article/6953cb1a1b2148c5b640f8b922f7ea45
Autor:
Mikael J. Pittet, Allon M. Klein, Ralph Weissleder, Virginia Savova, Rainer H. Kohler, Maaz S. Ahmed, Jeremy Quintana, Michael F. Cuccarese, Christopher B. Rodell, Angela N. Marquard, Melissa M. Sprachman, Jeremy Gungabeesoon, Marie Siwicki, Ruben Bill, Yunkang Lin, Nicolas A. Gort-Freitas, Steffen Rickelt, Angela E. Zou, Marius Messemaker, Camilla Engblom, Rapolas Zilionis, Christina Pfirschke
Supplementary Data from Macrophage-Targeted Therapy Unlocks Antitumoral Cross-talk between IFNγ-Secreting Lymphocytes and IL12-Producing Dendritic Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03be49f542113058bc6ec50af244fe65
https://doi.org/10.1158/2326-6066.22544211
https://doi.org/10.1158/2326-6066.22544211
Autor:
Mikael J. Pittet, Allon M. Klein, Ralph Weissleder, Virginia Savova, Rainer H. Kohler, Maaz S. Ahmed, Jeremy Quintana, Michael F. Cuccarese, Christopher B. Rodell, Angela N. Marquard, Melissa M. Sprachman, Jeremy Gungabeesoon, Marie Siwicki, Ruben Bill, Yunkang Lin, Nicolas A. Gort-Freitas, Steffen Rickelt, Angela E. Zou, Marius Messemaker, Camilla Engblom, Rapolas Zilionis, Christina Pfirschke
Macrophages often abound within tumors, express colony-stimulating factor 1 receptor (CSF1R), and are linked to adverse patient survival. Drugs blocking CSF1R signaling have been used to suppress tumor-promoting macrophage responses; however, their m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbe5dea6561f080330bae8bd2e02da5
https://doi.org/10.1158/2326-6066.c.6550572.v1
https://doi.org/10.1158/2326-6066.c.6550572.v1
Autor:
Jeremy Quintana, Virginia Savova, Ralph Weissleder, Maaz S. Ahmed, Michael F. Cuccarese, Nicolas A. Gort-Freitas, Mikael J. Pittet, Allon M. Klein, Steffen Rickelt, Melissa M. Sprachman, Christina Pfirschke, Christopher B. Rodell, Angela N. Marquard, Jeremy Gungabeesoon, Ruben Bill, Rainer H. Kohler, Rapolas Zilionis, Marius Messemaker, Angela E. Zou, Camilla Engblom, Yunkang Lin, Marie Siwicki
Publikováno v:
Cancer Immunology Research. 10:40-55
Macrophages often abound within tumors, express colony-stimulating factor 1 receptor (CSF1R), and are linked to adverse patient survival. Drugs blocking CSF1R signaling have been used to suppress tumor-promoting macrophage responses; however, their m
Autor:
Claire D. McWhite, Wisath Sae-Lee, Yaning Yuan, Anna L. Mallam, Nicolas A. Gort-Freitas, Silvia Ramundo, Masayuki Onishi, Edward M. Marcotte
Variability of proteins at the sequence level creates an enormous potential for proteome complexity. Exploring the depths and limits of this complexity is an ongoing goal in biology. Here, we systematically survey human and plant high-throughput bott
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7c797c898fadd70a3303859b7610b9e
https://doi.org/10.1101/2022.09.21.508930
https://doi.org/10.1101/2022.09.21.508930
Autor:
Jeremy Gungabeesoon, Nicolas A. Gort-Freitas, Máté Kiss, Evangelia Bolli, Marius Messemaker, Marie Siwicki, Mehdi Hicham, Ruben Bill, Peter Koch, Chiara Cianciaruso, Florent Duval, Christina Pfirschke, Michael Mazzola, Solange Peters, Krisztian Homicsko, Christopher Garris, Ralph Weissleder, Allon M. Klein, Mikael J. Pittet
Publikováno v:
Cell. 186:1448-1464.e20
Neutrophils accumulate in solid tumors, and their abundance correlates with poor prognosis. Neutrophils are not homogeneous, however, and could play different roles in cancer therapy. Here, we investigate the role of neutrophils in immunotherapy, lea
Autor:
Nicolas A. Gort-Freitas, Christina Pfirschke, Anna Kohl, Doron Merkler, Marie Siwicki, Yoshiko Iwamoto, Chiara Cianciaruso, Rapolas Zilionis, Marius Messemaker, Sara I. Pai, John E. Mindur, Montserrat Fraga, Pierre-Yves Dietrich, Angela E. Zou, Alexander Coukos, Christine Sempoux, Yi-Jang Lin, Nilesh Talele, Cecile Piot, Thibaud Koessler, Alexandre Wicky, Rakesh K. Jain, Yunkang Lin, Mikael J. Pittet, Rainer H. Kohler, Ruben Bill, Christopher Garris, Camilla Engblom, Jeremy Gungabeesoon, Allon M. Klein, Claudio deVito, Olivier Michielin, Ralph Weissleder, Evangelia Bolli, Genevieve M. Gerhard, Mari Mino-Kenudson
Publikováno v:
Sci Immunol
Science Immunology, Vol. 6, No 61 (2021) P. eabi7083
Science Immunology, Vol. 6, No 61 (2021) P. eabi7083
Immunotherapy is revolutionizing cancer treatment but is often restricted by toxicities. What distinguishes adverse events from concomitant antitumor reactions is poorly understood. Here, using anti-CD40-treatment in mice as a model of Th1-promoting