Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Nicolas Pilon"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Researchers who aim to globally analyze the gastrointestinal immune system via flow cytometry have many protocol options to choose from, with specifics generally tied to gut wall layers of interest. To get a clearer idea of the approach we s
Externí odkaz:
https://doaj.org/article/270efeabf44d45078fe768a7a93952b0
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
Previously focused primarily on enteric neurons, studies of the enteric nervous system (ENS) in both health and disease are now broadening to recognize the equally significant role played by enteric glial cells (EGCs). Commensurate to the vast array
Externí odkaz:
https://doaj.org/article/a6e0d1f83ea742e2ba606474def06389
Autor:
Armelle Tchoumi Neree, Rodolphe Soret, Lucia Marcocci, Paola Pietrangeli, Nicolas Pilon, Mircea Alexandru Mateescu
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-13 (2020)
Abstract Excess of histamine in gut lumen generates a pronounced gastrointestinal discomfort, which may include diarrhea and peristalsis dysfunctions. Deleterious effects of histamine can be alleviated with antihistamine drugs targeting histamine rec
Externí odkaz:
https://doaj.org/article/defcbb39185343958456791d41819c58
Autor:
Tatiana Cardinal, Karl-Frédérik Bergeron, Rodolphe Soret, Ouliana Souchkova, Christophe Faure, Amélina Guillon, Nicolas Pilon
Publikováno v:
PLoS Genetics, Vol 16, Iss 9, p e1009008 (2020)
Hirschsprung disease (HSCR) is a complex genetic disorder of neural crest development resulting in incomplete formation of the enteric nervous system (ENS). This life-threatening neurocristopathy affects 1/5000 live births, with a currently unexplain
Externí odkaz:
https://doaj.org/article/db39d388b3b143c3940d826ffa28243a
Autor:
Karl-F. Bergeron, Chloé M. A. Nguyen, Tatiana Cardinal, Baptiste Charrier, David W. Silversides, Nicolas Pilon
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 11, Pp 1283-1293 (2016)
Waardenburg syndrome is a neurocristopathy characterized by a combination of skin and hair depigmentation, and inner ear defects. In the type 4 form, these defects show comorbidity with Hirschsprung disease, a disorder marked by an absence of neural
Externí odkaz:
https://doaj.org/article/4d3f78ca09cc4d9683419bc4159cfa97
Autor:
Nicolas Pilon
Publikováno v:
International journal of molecular sciences. 23(22)
The first volume of this Special Issue met its goal of covering several aspects regarding both the normal and abnormal development of neural crest cells, which form a truly unique multipotent and highly migratory cell population that only exists in v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3920defcda0fd6e98a1c4c170316c5
https://pubmed.ncbi.nlm.nih.gov/36430161
https://pubmed.ncbi.nlm.nih.gov/36430161
Autor:
Nicolas Pilon
Publikováno v:
Trends in Molecular Medicine. 27:451-468
Neurocristopathies form a heterogeneous group of rare diseases caused by abnormal development of neural crest cells. Heterogeneity of neurocristopathies directly relates to the nature of these migratory and multipotent cells, which generate dozens of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02a77d61307545fe46e3af0036ae9e5
https://doi.org/10.1016/j.molmed.2021.01.009
https://doi.org/10.1016/j.molmed.2021.01.009
Autor:
Sephora Sallis, Félix-Antoine Bérubé-Simard, Benoit Grondin, Elizabeth Leduc, Fatiha Azouz, Catherine Bélanger, Nicolas Pilon
Publikováno v:
Life Science Alliance. 6:e202302133
CHARGE syndrome is a neural crest-related disorder mainly caused by mutation of the chromatin remodeler-coding geneCHD7. Alternative causes include mutation of other chromatin and/or splicing factors. One of these additional players is the poorly cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a9e13a9ec4afb3eefc070b7a7112dfec
https://doi.org/10.26508/lsa.202302133
https://doi.org/10.26508/lsa.202302133
Autor:
Rodolphe Soret, Nicolas Pilon
Publikováno v:
Bio-Protocol, Vol 6, Iss 17 (2016)
Hirschsprung disease (HSCR), also named aganglionic megacolon, is a severe congenital malformation characterized by a lack of enteric nervous system (ENS) in the terminal regions of the bowel (Bergeron et al., 2013). As the ENS notably regulates moti
Externí odkaz:
https://doaj.org/article/5b3f5655bc1c4476b2b312a3c23f6a95
Publikováno v:
Pigment Cell & Melanoma Research. 34:648-654
For a long time, melanocytes were believed to be exclusively derived from neural crest cells migrating from the neural tube toward the developing skin. This notion was then challenged by studies suggesting that melanocytes could also be made from neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94006445cc00756b11b8ec9362f0ed82
https://doi.org/10.1111/pcmr.12938
https://doi.org/10.1111/pcmr.12938