Zobrazeno 1 - 10
of 194
pro vyhledávání: '"Nicolas, Vitale"'
Autor:
Michael Okafor, Olivia Champomier, Laurent Raibaut, Sebahat Ozkan, Naima El Kholti, Stéphane Ory, Sylvette Chasserot-Golaz, Stéphane Gasman, Christelle Hureau, Peter Faller, Nicolas Vitale
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
CPPs, or Cell-Penetrating Peptides, offer invaluable utility in disease treatment due to their ability to transport various therapeutic molecules across cellular membranes. Their unique characteristics, such as biocompatibility and low immunogenicity
Externí odkaz:
https://doaj.org/article/949034d1ec704a999b452180d4146f2c
Autor:
Qili Wang, Alexander Wolf, Sebahat Ozkan, Ludovic Richert, Yves Mely, Sylvette Chasserot-Golaz, Stéphane Ory, Stéphane Gasman, Nicolas Vitale
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Although there is mounting evidence indicating that lipids serve crucial functions in cells and are implicated in a growing number of human diseases, their precise roles remain largely unknown. This is particularly true in the case of neurosecretion,
Externí odkaz:
https://doaj.org/article/bd8a62949fee4ab58c8f7e73dd9ade3a
Autor:
Christian Lévêque, Yves Maulet, Qili Wang, Marion Rame, Léa Rodriguez, Sumiko Mochida, Marion Sangiardi, Fahamoe Youssouf, Cécile Iborra, Michael Seagar, Nicolas Vitale, Oussama El Far
Publikováno v:
Cells, Vol 12, Iss 5, p 750 (2023)
V-ATPase is an important factor in synaptic vesicle acidification and is implicated in synaptic transmission. Rotation in the extra-membranous V1 sector drives proton transfer through the membrane-embedded multi-subunit V0 sector of the V-ATPase. Int
Externí odkaz:
https://doaj.org/article/59f893d975e14efca870c5732bb32957
Publikováno v:
Bio-Protocol, Vol 11, Iss 12 (2021)
Over the last decade, lipids have emerged as possessing an ever-increasing number of key functions, especially in membrane trafficking. For instance, phosphatidic acid (PA) has been proposed to play a critical role in different steps along the secret
Externí odkaz:
https://doaj.org/article/ea80035a3c7d4cc58168b7da7e662395
Autor:
Emeline Tanguy, Tamou Thahouly, Cathy Royer, Valérie Demais, Stéphane Gasman, Sylvette Chasserot-Golaz, Nicolas Vitale
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100464- (2021)
Summary: The glycerophospholipid phosphatidic acid (PA) is a key player in regulated exocytosis, but little is known about its localization at the plasma membrane. Here, we provide a protocol for precisely determining the spatial distribution of PA a
Externí odkaz:
https://doaj.org/article/3bbd5144a38744fe9af8320d9c998599
Autor:
Shima Ghoroghi, Benjamin Mary, Annabel Larnicol, Nandini Asokan, Annick Klein, Naël Osmani, Ignacio Busnelli, François Delalande, Nicodème Paul, Sébastien Halary, Frédéric Gros, Laetitia Fouillen, Anne-Marie Haeberle, Cathy Royer, Coralie Spiegelhalter, Gwennan André-Grégoire, Vincent Mittelheisser, Alexandre Detappe, Kendelle Murphy, Paul Timpson, Raphaël Carapito, Marcel Blot-Chabaud, Julie Gavard, Christine Carapito, Nicolas Vitale, Olivier Lefebvre, Jacky G Goetz, Vincent Hyenne
Publikováno v:
eLife, Vol 10 (2021)
Cancer extracellular vesicles (EVs) shuttle at distance and fertilize pre-metastatic niches facilitating subsequent seeding by tumor cells. However, the link between EV secretion mechanisms and their capacity to form pre-metastatic niches remains obs
Externí odkaz:
https://doaj.org/article/8b6c4beb19a94bea955052e913d775d6
Autor:
Najwa Skafi, Solenne Pelletier, Christophe Soulage, Sophie Reibel, Nicolas Vitale, Eva Hamade, Bassan Badran, Rene Buchet, David Magne, Dennis Fouque, Saida Mebarek, Leyre Brizuela
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100639- (2020)
Externí odkaz:
https://doaj.org/article/0deb16c689334949ab6092d07a6c2b6b
Autor:
Frank W. Pfrieger, Nicolas Vitale
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 12, Pp 2255-2261 (2018)
Eukaryotic cells employ distinct means to release specific signals and material. Research within the last decade has identified different types of membrane-enclosed structures collectively called extracellular vesicles (EVs) as one of them. EVs fall
Externí odkaz:
https://doaj.org/article/d9c61f39cf944a80a13e6eb48b015f7d
Autor:
Christophe Chopard, Phuoc Bao Viet Tong, Petra Tóth, Malvina Schatz, Hocine Yezid, Solène Debaisieux, Clément Mettling, Antoine Gross, Martine Pugnière, Annie Tu, Jean-Marc Strub, Jean-Michel Mesnard, Nicolas Vitale, Bruno Beaumelle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
It is not clear whether and how incoming HIV-1 Tat accumulates in uninfected cells. Here, Chopard et al. show that, in uninfected cells, incoming Tat is palmitoylated on Cys31 by DHHC-20, which increases its affinity for PI(4,5)P2 and results in its
Externí odkaz:
https://doaj.org/article/0b76da00f3d140a9bf12b239560dc94a
Autor:
Marion Gabel, Cathy Royer, Tamou Thahouly, Valérie Calco, Stéphane Gasman, Marie-France Bader, Nicolas Vitale, Sylvette Chasserot-Golaz
Publikováno v:
Cells, Vol 9, Iss 9, p 2059 (2020)
Annexin A2 (AnxA2) is a calcium- and lipid-binding protein involved in neuroendocrine secretion where it participates in the formation and/or stabilization of lipid micro-domains required for structural and spatial organization of the exocytotic mach
Externí odkaz:
https://doaj.org/article/f45fefa09874490fa5428c5f41bd979f