Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicolas, Martinier"'
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23905 (2011)
BACKGROUND: Reactive astrocytes are implicated in the development and maintenance of neuroinflammation in the demyelinating disease multiple sclerosis (MS). The sphingosine kinase 1 (SphK1)/sphingosine1-phosphate (S1P) receptor signaling pathway is i
Externí odkaz:
https://doaj.org/article/7295950b5ea7447f81730db20ac7f508
Autor:
Marie José Frossard, Nicolas Martinier, Rosanna Pescini Gobert, Ursula Boschert, Corinne Brana, Timothy J. Seabrook
Publikováno v:
Neuropathology and Applied Neurobiology. 40:564-578
Aims Sphingosine-1-phosphate receptor (S1PR) modulating therapies are currently in the clinic or undergoing investigation for multiple sclerosis (MS) treatment. However, the expression of S1PRs is still unclear in the central nervous system under nor
Autor:
Corinne, Brana, Marie José, Frossard, Rosanna, Pescini Gobert, Nicolas, Martinier, Ursula, Boschert, Timothy J, Seabrook
Publikováno v:
Neuropathology and applied neurobiology. 40(5)
Sphingosine-1-phosphate receptor (S1PR) modulating therapies are currently in the clinic or undergoing investigation for multiple sclerosis (MS) treatment. However, the expression of S1PRs is still unclear in the central nervous system under normal c
Autor:
Beniwende Kabre, Maureen A. Su, Hélène Bour-Jordan, Dan Davini, Cedric Louvet, Wendy Rosenthal, Nicolas Martinier, Jason DeVoss, Mark S. Anderson, Jeffrey A. Bluestone
Publikováno v:
The Journal of experimental medicine, vol 206, iss 3
The Journal of Experimental Medicine
The Journal of Experimental Medicine
Autoimmune-prone nonobese diabetic mice deficient for B7-2 spontaneously develop an autoimmune peripheral neuropathy mediated by inflammatory CD4+ T cells that is reminiscent of Guillain-Barré syndrome and chronic inflammatory demyelinating polyneur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1024f1af3741b9e963cb61aded0c99d7
https://escholarship.org/uc/item/0kv943g8
https://escholarship.org/uc/item/0kv943g8
Autor:
Shirley Zhu, Cédric Louvet, Arthur Weiss, Gideon Bollag, Gregory L. Szot, Jiena Lang, Nicolas Martinier, Michael R. Lee, Jeffrey A. Bluestone
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(48)
The recent development of small-molecule tyrosine kinase (TK) inhibitors offers increasing opportunities for the treatment of autoimmune diseases. In this study, we investigated the potential of this new class of drugs to treat and cure type 1 diabet
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23905 (2011)
PLoS ONE
PLoS ONE
BACKGROUND: Reactive astrocytes are implicated in the development and maintenance of neuroinflammation in the demyelinating disease multiple sclerosis (MS). The sphingosine kinase 1 (SphK1)/sphingosine1-phosphate (S1P) receptor signaling pathway is i