Výsledky vyhledávání - "Nicolas, Marie"

Akademický článek

Publikováno v: Frontiers in Psychiatry, Vol 14 (2023)

The over-prescription of opioid analgesics is a growing problem in the field of addiction, which has reached epidemic-like proportions in North America. Over the past decade, oxycodone has gained attention as the leading opioid responsible for the No

Externí odkaz: https://doaj.org/article/fd7c0b1442fe43d59d3769aa4ea782f0

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Akademický článek

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Akademický článek

Effect of Monoclonal Antibody Blockade of Long Fragment Neurotensin on Weight Loss, Behavior, and Metabolic Traits After High-Fat Diet Induced Obesity

Autor: Zherui Wu, Nicolas Stadler, Amazigh Abbaci, Jin Liu, Agnès Boullier, Nicolas Marie, Olivier Biondi, Marthe Moldes, Romain Morichon, Bruno Feve, Olle Melander, Patricia Forgez

Publikováno v: Frontiers in Endocrinology, Vol 12 (2021)

BackgroundObesity is a major public health problem of our time as a risk factor for cardiometabolic disease and the available pharmacological tools needed to tackle the obesity pandemic are insufficient. Neurotensin (NTS) is a 13 amino acid peptide,

Externí odkaz: https://doaj.org/article/17486a3e01ca49d0b67a718be10d7ebc

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Akademický článek

Biased Opioid Ligands: Revolution or Evolution?

Autor: Florence Noble, Nicolas Marie

Publikováno v: Frontiers in Pain Research, Vol 2 (2021)

Opioid are the most powerful analgesics ever but their use is still limited by deleterious side effects such as tolerance, dependence, and respiratory depression that could eventually lead to a fatal overdose. The opioid crisis, mainly occurring in n

Externí odkaz: https://doaj.org/article/2dcf450cc48a48c8a44019a1b1059453

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Akademický článek

Management of Opioid Addiction With Opioid Substitution Treatments: Beyond Methadone and Buprenorphine

Autor: Florence Noble, Nicolas Marie

Publikováno v: Frontiers in Psychiatry, Vol 9 (2019)

With the opioid crisis in North America, opioid addiction has come in the spotlight and reveals the weakness of the current treatments. Two main opioid substitution therapies (OST) exist: buprenorphine and methadone. These two molecules are mu opioid

Externí odkaz: https://doaj.org/article/a07bd52991194c3491e632defc583e2d

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Evaluation of Specific Binding of [11C]RTI-97 to Kappa Opioid Receptor by Autoradiography and PET Imaging in Rat

Autor: Fabien Fillesoye, Florence Noble, Nicolas Marie, Méziane Ibazizène, Cécile Perrio

Publikováno v: ACS Medicinal Chemistry Letters. 12:1739-1744

Kappa opioid receptor (KOR) PET imaging remains attractive to understand the role of KOR in health and diseases and to help the development of drugs especially for psychiatric disorders such as depression, anxiety, and addiction. The potent and selec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3aef9880e7125efaa5a0967d96fcb1b7
https://doi.org/10.1021/acsmedchemlett.1c00369

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Amphiphilic Polyfluorinated Amino Ethers from Cyclic Sulfamidates

Autor: Nicolas Marie, Jun-An Ma, Dominique Cahard

Publikováno v: The Journal of organic chemistry. 87(24)

Regioselective ring opening of cyclic sulfamidates was achieved by means of nucleophilic polyfluorinated alkoxides to access achiral and chiral β- and γ-OR

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0616d734f5c6493dc1d3e265abb8093
https://pubmed.ncbi.nlm.nih.gov/36417566

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Almost periodic and periodic solutions of differential equations driven by the fractional Brownian motion with statistical application

Autor: Paul Raynaud de Fitte, Nicolas Marie

Publikováno v: Stochastics: An International Journal of Probability and Stochastic Processes
Stochastics: An International Journal of Probability and Stochastic Processes, Taylor & Francis: STM, Behavioural Science and Public Health Titles, 2021, 93 (6), pp.886-906. ⟨10.1080/17442508.2020.1815746⟩
Stochastics: An International Journal of Probability and Stochastic Processes, 2021, 93 (6), pp.886-906. ⟨10.1080/17442508.2020.1815746⟩

We show that the unique solution to a semilinear stochastic differential equation with almost periodic coefficients driven by a fractional Brownian motion is almost periodic in a sense related to random dynamical systems. This type of almost periodic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc593a8cad03d3ac4dd50fb15a1da1f6
https://doi.org/10.1080/17442508.2020.1815746

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