Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicolas, Loncle"'
Autor:
Federico Miozzo, Eva P. Valencia-Alarcón, Luca Stickley, Michaëla Majcin Dorcikova, Francesco Petrelli, Damla Tas, Nicolas Loncle, Irina Nikonenko, Peter Bou Dib, Emi Nagoshi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Mitochondrial dysfunction in dopaminergic neurons is a pathological hallmark of Parkinson’s disease. Here, the authors find a conserved mechanism by which a single transcription factor controls mitochondrial health in dopaminergic neurons during th
Externí odkaz:
https://doaj.org/article/5f787c1c5eac4589a8bc26327c5c282e
Autor:
Anne Zanchi, Michel Burnier, Marie‐Eve Muller, Arlène Ghajarzadeh‐Wurzner, Marc Maillard, Nicolas Loncle, Bastien Milani, Nathalie Dufour, Olivier Bonny, Menno Pruijm
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 13 (2020)
Background The sodium/glucose cotransporter 2 inhibitor empagliflozin has cardiorenal protective properties through mechanisms beyond glucose control. In this study we assessed whether empagliflozin modifies renal oxygenation as a possible mechanism
Externí odkaz:
https://doaj.org/article/59f69b1c06214c859127f567b5bff796
Autor:
Xiao Li, Mengmeng Liu, Xingjie Ren, Nicolas Loncle, Qun Wang, Rajitha-Udakara-Sampath Hemba-Waduge, Stephen H Yu, Muriel Boube, Henri-Marc G Bourbon, Jian-Quan Ni, Jun-Yuan Ji
Publikováno v:
PLoS Genetics, Vol 16, Iss 5, p e1008832 (2020)
Dysregulation of CDK8 (Cyclin-Dependent Kinase 8) and its regulatory partner CycC (Cyclin C), two subunits of the conserved Mediator (MED) complex, have been linked to diverse human diseases such as cancer. Thus, it is essential to understand the reg
Externí odkaz:
https://doaj.org/article/4e4346374603407a93e13c02794c0c5c
Autor:
Damla Tas, Luca Stickley, Federico Miozzo, Rafael Koch, Nicolas Loncle, Virginie Sabado, Bettina Gnägi, Emi Nagoshi
Publikováno v:
PLoS Genetics, Vol 14, Iss 3, p e1007271 (2018)
Forkhead box (FOXO) proteins are evolutionarily conserved, stress-responsive transcription factors (TFs) that can promote or counteract cell death. Mutations in FOXO genes are implicated in numerous pathologies, including age-dependent neurodegenerat
Externí odkaz:
https://doaj.org/article/76ad49edc742478ea214f2c49cd0b73e
Autor:
Nicolas Loncle, Menno Pruijm, Bastien Milani, Matthias Stuber, Jean Delacoste, Joao Miguel Lourenco, Wendy Brito, Philippe Braconnier, Marc Maillard, Michel Burnier
Publikováno v:
Journal of Hypertension. 38:159-166
OBJECTIVE There is increasing evidence that sodium can be stored in the skin and muscles without being osmotically active, yet whether acute changes in dietary sodium intake alter sweat and muscle sodium content has not been investigated previously.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec06b4155f91cba64d6e1cb461857c6e
https://doi.org/10.1097/hjh.0000000000002234
https://doi.org/10.1097/hjh.0000000000002234
Autor:
Nicolas Loncle, Mariëlle C. Hendriks-Balk, Michel Burnier, Antoine G. Schneider, Menno Pruijm, Jonas Garessus, Grégoire Wuerzner, Wendy Brito, Anna Vanelli
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 37(4)
Background Disturbances in renal microcirculation play an important role in the pathophysiology of chronic kidney disease (CKD), but the lack of easy accessible techniques hampers our understanding of the regulation of the renal microcirculation in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82998f3c6d4830d418330e5bed6e1311
https://pubmed.ncbi.nlm.nih.gov/33426563
https://pubmed.ncbi.nlm.nih.gov/33426563
Autor:
Federico, Miozzo, Eva P, Valencia-Alarcón, Luca, Stickley, Michaëla, Majcin Dorcikova, Francesco, Petrelli, Damla, Tas, Nicolas, Loncle, Irina, Nikonenko, Peter, Bou Dib, Emi, Nagoshi
Publikováno v:
Nature communications. 13(1)
Progressive degeneration of dopaminergic (DA) neurons in the substantia nigra is a hallmark of Parkinson's disease (PD). Dysregulation of developmental transcription factors is implicated in dopaminergic neurodegeneration, but the underlying molecula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe93aec3824d7c7bbe980ef32eb874ee
https://pubmed.ncbi.nlm.nih.gov/35301315
https://pubmed.ncbi.nlm.nih.gov/35301315
Autor:
Emi Nagoshi, Federico Miozzo, Michaela Dorcikova, Luca Stickely, Eva P. Valencia-Alarcón, Damla Tas, Irina Nikonenko, Peter Bou Dib, Nicolas Loncle
The degeneration of dopaminergic (DA) neurons in the substantia nigra is a hallmark of Parkinson’s disease (PD). Dysregulation of developmental transcription factors is implicated in dopaminergic neurodegeneration, but the underlying molecular mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b0a5b21e47eb15723abe56dd299c60f
https://doi.org/10.1101/2020.07.24.219246
https://doi.org/10.1101/2020.07.24.219246
Autor:
Grégoire Wuerzner, Anna Vannelli, Jonas Garessus, Menno Pruijm, Wendy Brito, Nicolas Loncle, Antoine G. Schneider
Publikováno v:
Nephrology Dialysis Transplantation. 35
Background and Aims Vascular factors such as capillary rarefaction, increased vascular stiffness and reduced vasodilatation due to endothelial dysfunction probably play an important role in the pathophysiology of chronic kidney disease (CKD). However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60a7dfd9456d861ac0c00b3633f302c6
https://doi.org/10.1093/ndt/gfaa142.p0677
https://doi.org/10.1093/ndt/gfaa142.p0677
Autor:
Wendy Brito, Matthias Stuber, Menno Pruijm, Jean Delacoste, Bastien Milani, Marc Maillard, Michel Burnier, Joao Miguel Lourenco, Nicolas Loncle, Philippe Braconnier
Publikováno v:
Nephrology Dialysis Transplantation. 34
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aa4f5a1180b4f9db1d60231b9634547
https://doi.org/10.1093/ndt/gfz103.sp042
https://doi.org/10.1093/ndt/gfz103.sp042