Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy.

Autor: Sophie Scialom, Georgia Malamut, Bertrand Meresse, Nicolas Guegan, Nicole Brousse, Virginie Verkarre, Coralie Derrieux, Elizabeth Macintyre, Philippe Seksik, Guillaume Savoye, Guillaume Cadiot, Lucine Vuitton, Lysiane Marthey, Franck Carbonnel, Nadine Cerf-Bensussan, Christophe Cellier

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0125024 (2015)

Background and objectivesAnti-hypertensive treatment with the angiotensin II receptor antagonist olmesartan is a rare cause of severe Sprue-like enteropathy. To substantiate the hypothesis that olmesartan interferes with gut immune homeostasis, clini

Externí odkaz: https://doaj.org/article/3a2eaa63d6d448c2a956974dda033ad1

Oncogenetic Landscape Of Lymphomagenesis In Coeliac Disease

Autor: Thierry Jo Molina, Ludovic Lhermitte, Christine Bole-Feysot, Georgia Malamut, Elizabeth Macintyre, Morgane Cheminant, Amélie Trinquand, Sophie Kaltenbach, Bruno Tesson, Olivier Hermine, David Sibon, Sofia Berrabah, Patrick Villarese, Christophe Cellier, Sherine Khater, Nicolas Guegan, Sascha Cording, Julie Bruneau, Marc Bras, Bertrand Meresse, Nadine Cerf-Bensussan, Vahid Asnafi, Michael Dussiot

ObjectiveEnteropathy-associated T-cell lymphoma (EATL) is a rare but severe complication of celiac disease (CeD), often preceded by low-grade clonal intraepithelial lymphoproliferation, referred to as type II refractory CeD (RCDII). Knowledge on unde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c331760793fdda3576de53d5c950fa5a
https://doi.org/10.1101/2020.09.07.275032

NKp46 is a diagnostic biomarker and may be a therapeutic target in gastrointestinal T-cell lymphoproliferative diseases: A CELAC study

Autor: Nicolas Guegan, Florence Lhospice, Sascha Cording, Amélie Trinquand, Julie Bruneau, Olivier Hermine, Virginie Verkarre, Nicole Brousse, Christophe Cellier, Georgia Malamut, Elizabeth Macintyre, Felipe Suarez, Laurent Frenzel, Vahid Asnafi, Morgane Cheminant, Sherine Khater, Bertrand Meresse, Ambroise Marçais, Nadine Cerf-Bensussan, Tom van Gils, Chris J. J. Mulder, Thierry Jo Molina, Ludovic Lhermitte, C. cile Bonnafous, David Sibon, Anne-Sophie Jannot, Richard Delarue, Laurent Pouyet

Publikováno v: Gut, 68(8), 1396-1405. BMJ Publishing Group
Gut
Gut, BMJ Publishing Group, 2019, 68 (8), pp.1396-1405. ⟨10.1136/gutjnl-2018-317371⟩
Cheminant, M, Bruneau, J, Malamut, G, Sibon, D, Guegan, N, van Gils, T, Cording, S, Trinquand, A, Verkarre, V, Lhermitte, L, Brousse, N, Jannot, A-S, Khater, S, Frenzel, L, Delarue, R, Suarez, F, Marçais, A, Mulder, C J J, Macintyre, E, Asnafi, V, Pouyet, L, Bonnafous, C C, Lhospice, F, Molina, T J, Meresse, B, Cellier, C, Cerf-Bensussan, N & Hermine, O 2019, ' NKp46 is a diagnostic biomarker and may be a therapeutic target in gastrointestinal T-cell lymphoproliferative diseases: A CELAC study ', Gut, vol. 68, no. 8, pp. 1396-1405 . https://doi.org/10.1136/gutjnl-2018-317371
Gut, 2019, 68 (8), pp.1396-1405. ⟨10.1136/gutjnl-2018-317371⟩

ObjectivesPrimary GI T-cell lymphoproliferative diseases (T-LPD) are heterogeneous entities, which raise difficult diagnosis and therapeutic challenges. We have recently provided evidences that lymphomas complicating coeliac disease (CD) arise from i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70bf16bc8e37754465b0cd121bf54c22
https://research.vumc.nl/en/publications/c070e3fd-4cc5-486e-8710-e1f8ba369480

Human ALPI deficiency causes inflammatory bowel disease and highlights a key mechanism of gut homeostasis

Autor: Claudio Romano, Paola De Angelis, Jie Pan, Marc Bras, Anne M. Griffiths, Karoline Fiedler, Paola Francalanci, Marianna Parlato, Nadine Cerf-Bensussan, Mohammed Zarhrate, Frank M. Ruemmele, Eileen Crowley, Aleixo M. Muise, Rémi Duclaux-Loras, Bernadette Bègue, Fabienne Charbit-Henrion, Nicolas Guegan, Julie Bruneau, Sabine Rakotobe, Nathalie Kapel, Marie‐Helene Le Du, Neil Warner

Publikováno v: EMBO Molecular Medicine
EMBO Molecular Medicine, 2018, 10 (4), pii: e8483. ⟨10.15252/emmm.201708483⟩
Paediatrics Publications
EMBO Molecular Medicine, Wiley Open Access, 2018, 10 (4), pii: e8483. ⟨10.15252/emmm.201708483⟩
EMBO Molecular Medicine, Vol 10, Iss 4, Pp n/a-n/a (2018)

International audience; Herein, we report the first identification of biallelic-inherited mutations inALPIas a Mendelian cause of inflammatory bowel disease in two unrelated patients.ALPIencodes for intestinal phosphatase alkaline, a brush border met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7da86880699d94a17afe66e1f93a1970
http://hdl.handle.net/11570/3134617

Gastrointestinal Disorder Associated with Olmesartan Mimics Autoimmune Enteropathy

Autor: Nicolas Guegan, Sophie Scialom, Nadine Cerf-Bensussan, Coralie Derrieux, Lysiane Marthey, Nicole Brousse, Georgia Malamut, Lucine Vuitton, Philippe Seksik, Virginie Verkarre, Guillaume Cadiot, Franck Carbonnel, Christophe Cellier, Bertrand Meresse, Elizabeth Macintyre, Guillaume Savoye

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2015, 10 (6), pp.e0125024. ⟨10.1371/journal.pone.0125024⟩
PLoS ONE, Public Library of Science, 2015, 10 (6), pp.e0125024. 〈10.1371/journal.pone.0125024〉
PLoS ONE, 2015, 10 (6), pp.e0125024. ⟨10.1371/journal.pone.0125024⟩
PLoS ONE, Vol 10, Iss 6, p e0125024 (2015)

International audience; Background and Objectives : Anti-hypertensive treatment with the angiotensin II receptor antagonist olmesartan is a rare cause of severe Sprue-like enteropathy. To substantiate the hypothesis that olmesartan interferes with gu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3162b469ff0ae03bf62457cd552a8ab6
https://hal.archives-ouvertes.fr/hal-01376850