Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicolas, Gourdin"'
Autor:
Yannis Morel, Eric Vivier, Benjamin Rossi, Laurent Gauthier, Anne-Laure Bauchet, Ariane Morel, Marielle Chiron, Angela Virone-Oddos, Jochen Beninga, Céline Nicolazzi, Céline Amara, Audrey Blanchard-Alvarez, Nicolas Gourdin, Jacqueline Courta, Alexandra Basset, Franceline Guillot, Gwendoline Grondin, Hélène Bonnevaux
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/a67c4a2df1c3401e92f632956b1f8420
Autor:
Ivan Perrot, Henri-Alexandre Michaud, Marc Giraudon-Paoli, Séverine Augier, Aurélie Docquier, Laurent Gros, Rachel Courtois, Cécile Déjou, Diana Jecko, Ondine Becquart, Hélène Rispaud-Blanc, Laurent Gauthier, Benjamin Rossi, Stéphanie Chanteux, Nicolas Gourdin, Beatrice Amigues, Alain Roussel, Armand Bensussan, Jean-François Eliaou, Jérémy Bastid, François Romagné, Yannis Morel, Emilie Narni-Mancinelli, Eric Vivier, Carine Paturel, Nathalie Bonnefoy
Publikováno v:
Cell Reports, Vol 27, Iss 8, Pp 2411-2425.e9 (2019)
Summary: Immune checkpoint inhibitors have revolutionized cancer treatment. However, many cancers are resistant to ICIs, and the targeting of additional inhibitory signals is crucial for limiting tumor evasion. The production of adenosine via the seq
Externí odkaz:
https://doaj.org/article/5587ee70bc8c4270948f7103cc944bcd
Autor:
Christine Ménétrier-Caux, Christophe Caux, Pedro Romero, Jérôme Guitton, Bertrand Dubois, Julien C. Marie, Olivier Tredan, Nicolas Chopin, Isabelle Durand, Julien Faget, David Bauché, Camilla Jandus, Christelle Machon, Selena Vigano, Céline Rodriguez, Marion Bossennec, Nicolas Gourdin
Th1.17 characteristics of CD73+ CD4+ Teff based on the expression of CXCR3, CCR6, CRTH2, the migration in response to CXCL10 or CCL20 gradient and the MDR-1-specific Rhodamine 123 exclusion assay
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::097ad743e952efb1131b9a72511cbb41
https://doi.org/10.1158/0008-5472.22418177
https://doi.org/10.1158/0008-5472.22418177
Autor:
Christine Ménétrier-Caux, Christophe Caux, Pedro Romero, Jérôme Guitton, Bertrand Dubois, Julien C. Marie, Olivier Tredan, Nicolas Chopin, Isabelle Durand, Julien Faget, David Bauché, Camilla Jandus, Christelle Machon, Selena Vigano, Céline Rodriguez, Marion Bossennec, Nicolas Gourdin
The production of CD73-derived adenosine (Ado) by Tregs has been proposed as a resistance mechanism to anti-PD-1 therapy in murine tumor models. We reported that human Tregs express the ectonucleotidase CD39, which generates AMP from ATP, but do not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b854f86c42fee472d126e8e9f216df0e
https://doi.org/10.1158/0008-5472.c.6510053
https://doi.org/10.1158/0008-5472.c.6510053
Autor:
Laurent Gauthier, Angela Virone-Oddos, Jochen Beninga, Benjamin Rossi, Céline Nicolazzi, Céline Amara, Audrey Blanchard-Alvarez, Nicolas Gourdin, Jacqueline Courta, Alexandra Basset, Magali Agnel, Franceline Guillot, Gwendoline Grondin, Hélène Bonnevaux, Anne-Laure Bauchet, Ariane Morel, Yannis Morel, Marielle Chiron, Eric Vivier
Publikováno v:
Nature Biotechnology.
CD123, the alpha chain of the IL-3 receptor, is an attractive target for acute myeloid leukemia (AML) treatment. However, cytotoxic antibodies or T cell engagers targeting CD123 had insufficient efficacy or safety in clinical trials. We show that exp
Autor:
Alexandre Tang, Laurent Gauthier, Jochen Beninga, Benjamin Rossi, Nicolas Gourdin, Audrey Blanchard-Alvarez, Céline Amara, Jacqueline Courta, Alexandra Basset, Dorothee Bourges, Alexandre Desjonqueres, Emmanuelle Menoret, Catherine Pellat-Deceunynck, Philippe Moreau, Yannis Morel, Marielle Chiron, Angela Virone-Oddos, Eric Vivier
Publikováno v:
Blood. 140:9985-9986
Autor:
Alexandre Tang, Laurent Gauthier, Jochen Beninga, Benjamin Rossi, Nicolas Gourdin, Audrey Blanchard-Alvarez, Céline Amara, Jacqueline Courta, Alexandra Basset, Dorothée Bourges, Alexandre Desjonqueres, Emmanuelle Menoret, Catherine Pellat-Deceunynck, Philippe Moreau, Yannis Morel, Marielle Chiron, Eric Vivier, Angela Virone-Oddos
Publikováno v:
Cancer Research. 83:2960-2960
Multiple Myeloma (MM) is the second most prevalent hematopoietic malignancy, representing 10% of total blood cancers. Despite the emergence of new therapies, it is still an incurable disease. Safe, potent and innovative approaches with long lasting b
Autor:
Yann Kieffer, Monika Licaj, Rana Mhaidly, Nicolas Gourdin, Carine Paturel, Ariane Morel, Ilaria Magagna, Fatima Mechta-Grigoriou, Anne Vincent-Salomon, Pascale Andre
Publikováno v:
Cancers; Volume 13; Issue 23; Pages: 5878
Cancers, Vol 13, Iss 5878, p 5878 (2021)
Cancers
Cancers, Vol 13, Iss 5878, p 5878 (2021)
Cancers
Simple Summary Recent findings have revealed the contribution of cancer-associated fibroblasts (CAF) in immune escape in breast cancer. Still, how to specifically target immunosuppressive CAF remains an unmet medical question. Here, we provide a prom
Autor:
Laurent Gauthier, Angela Virone-Oddos, Jochen Beninga, Benjamin Rossi, Céline Nicolazzi, Céline Amara, Audrey Blanchard-Alvarez, Nicolas Gourdin, Jacqueline Courta, Alexandra Basset, Franceline Guillot, Gwendoline Grondin, Hélène Bonnevaux, Anne-Laure Bauchet, Ariane Morel, Yannis Morel, Marielle Chiron, Eric Vivier
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
BackgroundThere is a clear need for targeted therapies to treat acute myeloid leukemia (AML), the most common acute leukemia in adults. CD123 (IL-3 receptor alpha chain) is an attractive target for AML treatment.1 However, cytotoxic antibody targetin
Autor:
Olivier Demaria, Laurent Gauthier, Marie Vetizou, Audrey Blanchard Alvarez, Constance Vagne, Guillaume Habif, Luciana Batista, William Baron, Nourhène Belaïd, Mathilde Girard-Madoux, Cedric Cesari, Melody Caratini, Frédéric Bosco, Olivier Benac, Julie Lopez, Aurore Fenis, Justine Galluso, Sylvia Trichard, Barbara Carrette, Florent Carrette, Aurélie Maguer, Solène Jaubert, Audrey Sansaloni, Robin Letay-Drouet, Camille Kosthowa, Naouel Lovera, Arnaud Dujardin, Fabien Chanuc, Mélanie Le Van, Sivan Bokobza, Nicolas Jarmuzynski, Camille Fos, Nicolas Gourdin, Romain Remark, Eric Lechevallier, Nicolas Fakhry, Sébastien Salas, Jean-Laurent Deville, Roger Le Grand, Cécile Bonnafous, Lukas Vollmy, Agnès Represa, Sabrina Carpentier, Benjamin Rossi, Ariane Morel, Stéphanie Cornen, Ivan Perrot, Yannis Morel, Eric Vivier
Publikováno v:
Cell Reports Medicine
Cell Reports Medicine, 2022, 3 (10), pp.100783. ⟨10.1016/j.xcrm.2022.100783⟩
Cell Reports Medicine, 2022, 3 (10), pp.100783. ⟨10.1016/j.xcrm.2022.100783⟩
International audience; Harnessing innate immunity is emerging as a promising therapeutic approach in cancer. We report here the design of tetraspecific molecules engaging natural killer (NK) cell-activating receptors NKp46 and CD16a, the β-chain of