Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Nicolas, Demaurex"'
Autor:
Amado Carreras-Sureda, Xin Zhang, Loann Laubry, Jessica Brunetti, Stéphane Koenig, Xiaoxia Wang, Cyril Castelbou, Claudio Hetz, Yong Liu, Maud Frieden, Nicolas Demaurex
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113540- (2023)
Summary: Store-operated Ca2+ entry (SOCE) mediated by stromal interacting molecule (STIM)-gated ORAI channels at endoplasmic reticulum (ER) and plasma membrane (PM) contact sites maintains adequate levels of Ca2+ within the ER lumen during Ca2+ signa
Externí odkaz:
https://doaj.org/article/77b99e83530e45649923a4aecc64dab4
Publikováno v:
Contact, Vol 6 (2023)
In this news and views, we discuss our recent publication where we described how ER-PM membrane contact sites (MCS) are modulated during store operated calcium entry (SOCE). We also examine why enforcing ER-PM MCS by tethering proteins does not not e
Externí odkaz:
https://doaj.org/article/1497cf777757484184e4abc422b969fa
Autor:
Amado Carreras-Sureda, Laurence Abrami, Kim Ji-Hee, Wen-An Wang, Christopher Henry, Maud Frieden, Monica Didier, F Gisou van der Goot, Nicolas Demaurex
Publikováno v:
eLife, Vol 10 (2021)
Efficient immune responses require Ca2+ fluxes across ORAI1 channels during engagement of T cell receptors (TCR) at the immune synapse (IS) between T cells and antigen presenting cells. Here, we show that ZDHHC20-mediated S-acylation of the ORAI1 cha
Externí odkaz:
https://doaj.org/article/ad6d37568ea5409c901775a30f909b1b
Autor:
Sophia Maschalidi, Paula Nunes-Hasler, Clarissa R Nascimento, Ignacio Sallent, Valérie Lannoy, Meriem Garfa-Traore, Nicolas Cagnard, Fernando E. Sepulveda, Pablo Vargas, Ana-Maria Lennon-Duménil, Peter van Endert, Thierry Capiod, Nicolas Demaurex, Guillaume Darrasse-Jèze, Bénédicte Manoury
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+ entry in response, a process associated with dendritic cell (DC) functions. Here, the authors show that optimal antigen cross-presentation in DCs requires the association o
Externí odkaz:
https://doaj.org/article/3df7bd0b89fc4e89876f33ce40769f73
Autor:
Paula Nunes-Hasler, Sophia Maschalidi, Carla Lippens, Cyril Castelbou, Samuel Bouvet, Daniele Guido, Flavien Bermont, Esen Y. Bassoy, Nicolas Page, Doron Merkler, Stéphanie Hugues, Denis Martinvalet, Bénédicte Manoury, Nicolas Demaurex
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions. Here the authors show STIM1 is the major isoform controlling SOCE in mouse dendritic cells and
Externí odkaz:
https://doaj.org/article/d16f804a8f3d4c7abd46394836e7b3e1
Publikováno v:
Journal of Cell Science. 136
The coronavirus SARS-CoV-2, the agent of the deadly COVID-19 pandemic, is an enveloped virus propagating within the endocytic and secretory organelles of host mammalian cells. Enveloped viruses modify the ionic homeostasis of organelles to render the
Changes in membrane phosphoinositides and local Ca2+elevations at sites of particle capture coordinate the dynamic remodeling of the actin cytoskeleton during phagocytosis. Here, we show that the phosphatidylinositol (PI) transfer proteins PITPNM1 (N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aaa1acc6f5b64efa9f3f827223de6573
https://doi.org/10.1101/2022.12.21.521447
https://doi.org/10.1101/2022.12.21.521447
Autor:
Shane Austin, Ronald Mekis, Sami E M Mohammed, Mariafrancesca Scalise, Wen‐An Wang, Michele Galluccio, Christina Pfeiffer, Tamara Borovec, Katja Parapatics, Dijana Vitko, Nora Dinhopl, Nicolas Demaurex, Keiryn L Bennett, Cesare Indiveri, Karin Nowikovsky
Publikováno v:
EMBO reports. 23
Publikováno v:
Contact, Vol 1 (2018)
Mitochondria undergo spontaneous transient elevations in matrix pH associated with drops in mitochondrial membrane potential. These mitopHlashes require a functional respiratory chain and the profusion protein optic atrophy 1, but their mechanistic b
Externí odkaz:
https://doaj.org/article/079ec1647eda4189bcab405c8dccad53
Autor:
Shane, Austin, Ronald, Mekis, Sami E M, Mohammed, Mariafrancesca, Scalise, Wen-An, Wang, Michele, Galluccio, Christina, Pfeiffer, Tamara, Borovec, Katja, Parapatics, Dijana, Vitko, Nora, Dinhopl, Nicolas, Demaurex, Keiryn L, Bennett, Cesare, Indiveri, Karin, Nowikovsky
Publikováno v:
EMBO reports. 23(12)
Mitochondrial Ca