Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Nicolas, Cruz"'
Autor:
Lange, Christoph, Thiele, Isabel, Santolin, Lara, Riedel, Sebastian L., Borisyak, Maxim, Neubauer, Peter, Bournazou, M. Nicolas Cruz
In biotechnology Raman Spectroscopy is rapidly gaining popularity as a process analytical technology (PAT) that measures cell densities, substrate- and product concentrations. As it records vibrational modes of molecules it provides that information
Externí odkaz:
http://arxiv.org/abs/2402.00851
Mechanistic growth models play a major role in bioprocess engineering, design, and control. Their reasonable predictive power and their high level of interpretability make them an essential tool for computer aided engineering methods. Additionally, s
Externí odkaz:
http://arxiv.org/abs/2312.03427
Autor:
Krausch, Niels, Doff-Sotta, Martin, Canon, Mark, Neubauer, Peter, Bournazou, Mariano Nicolas Cruz
Bioprocesses are often characterized by nonlinear and uncertain dynamics. This poses particular challenges in the context of model predictive control (MPC). Several approaches have been proposed to solve this problem, such as robust or stochastic MPC
Externí odkaz:
http://arxiv.org/abs/2312.00847
Autor:
Kim, Jong Woo, Krausch, Niels, Aizpuru, Judit, Barz, Tilman, Lucia, Sergio, Neubauer, Peter, Bournazou, Mariano Nicolas Cruz
We discuss the application of a nonlinear model predictive control (MPC) and a moving horizon estimation (MHE) to achieve an optimal operation of \textit{E. coli} fed-batch cultivations with intermittent bolus feeding. 24 parallel experiments were co
Externí odkaz:
http://arxiv.org/abs/2203.07211
Autor:
Kim, Jong Woo, Krausch, Niels, Aizpuru, Judit, Barz, Tilman, Lucia, Sergio, Martínez, Ernesto C., Neubauer, Peter, Bournazou, Mariano Nicolas Cruz
Optimal experimental design for parameter precision attempts to maximize the information content in experimental data for a most effective identification of parametric model. With the recent developments in miniaturization and parallelization of cult
Externí odkaz:
http://arxiv.org/abs/2112.10548
Publikováno v:
AIP Advances, Vol 14, Iss 1, Pp 015156-015156-16 (2024)
Spiders utilize their fine silk fibers for their aerial dispersal, known as ballooning. With this method, spiders can disperse hundreds of kilometers, reaching as high as 4.5 km. However, the passive dynamics of a ballooning model (a highly flexible
Externí odkaz:
https://doaj.org/article/28a346f42a93412ea1c73f602294efb8
To date, a large number of experiments are performed to develop a biochemical process. The generated data is used only once, to take decisions for development. Could we exploit data of already developed processes to make predictions for a novel proce
Externí odkaz:
http://arxiv.org/abs/2011.13863
Autor:
Jared Kopelman, Timothy A. Keller, Benjamin Panny, Angela Griffo, Michelle Degutis, Crystal Spotts, Nicolas Cruz, Elizabeth Bell, Kevin Do-Nguyen, Meredith L. Wallace, Sanjay J. Mathew, Robert H. Howland, Rebecca B. Price
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Intravenous ketamine is posited to rapidly reverse depression by rapidly enhancing neuroplasticity. In human patients, we quantified gray matter microstructural changes on a rapid (24-h) timescale within key regions where neuroplasticity enh
Externí odkaz:
https://doaj.org/article/75a96ee47abf4bd6bca4f81ec2299f6e
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Bioengineering, Vol 11, Iss 2, p 107 (2024)
Miniaturized cultivation systems offer the potential to enhance experimental throughput in bioprocess development. However, they usually lack the miniaturized pumps necessary for fed-batch mode, which is commonly employed in industrial bioprocesses.
Externí odkaz:
https://doaj.org/article/1c381ce485f74f36a6a0ded6589967d2