Výsledky vyhledávání - "Nicolas, Chabot"

Akademický článek

Contribution of markers of adiposopathy and adipose cell size in predicting insulin resistance in women of varying age and adiposity

Autor: Eve-Julie Tremblay, André Tchernof, Mélissa Pelletier, Nicolas Chabot, Denis R. Joanisse, Pascale Mauriège

Publikováno v: Adipocyte, Vol 11, Iss 1, Pp 175-189 (2022)

Adipose tissue (AT) dysfunctions, such as adipocyte hypertrophy, macrophage infiltration and secretory adiposopathy (low plasma adiponectin/leptin, A/L, ratio), associate with metabolic disorders. However, no study has compared the relative contribut

Externí odkaz: https://doaj.org/article/29bf7e91b10b4ae0aa5849655e8089db

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Akademický článek

Plasma membrane factor XIIIA transglutaminase activity regulates osteoblast matrix secretion and deposition by affecting microtubule dynamics.

Autor: Hadil F Al-Jallad, Vamsee D Myneni, Sarah A Piercy-Kotb, Nicolas Chabot, Amina Mulani, Jeffrey W Keillor, Mari T Kaartinen

Publikováno v: PLoS ONE, Vol 6, Iss 1, p e15893 (2011)

Transglutaminase activity, arising potentially from transglutaminase 2 (TG2) and Factor XIIIA (FXIIIA), has been linked to osteoblast differentiation where it is required for type I collagen and fibronectin matrix deposition. In this study we have us

Externí odkaz: https://doaj.org/article/391e9309bc0b4d7599052a630beb9019

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Engineering of Candida antarctica lipase B for poly(ε-caprolactone) synthesis

Autor: Magali Remaud-Simeon, Isabelle André, David Guieysse, Stéphane Emond, Frédéric Peruch, Cedric Montanier, Nicolas Chabot

Publikováno v: European Polymer Journal
European Polymer Journal, Elsevier, 2017, pp.809-819. ⟨10.1016/j.eurpolymj.2017.07.029⟩
European Polymer Journal, Elsevier, 2017, 95, pp.809-819. ⟨10.1016/j.eurpolymj.2017.07.029⟩
European Polymer Journal, 2017, 95, pp.809-819. ⟨10.1016/j.eurpolymj.2017.07.029⟩
European Polymer Journal, Elsevier, 2017, 95, pp.809-819. 〈10.1016/j.eurpolymj.2017.07.029〉

Development of novel synthetic routes based on more eco-friendly processes, such as enzyme-based catalysis, are in great demand to produce biopolymers. Among them, enzymatic Ring Opening Polymerization (eROP) of lactones using lipases, such as Candid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc70150010f347c4cce0ddc04e416067
https://doi.org/10.1016/j.eurpolymj.2017.07.029

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Deinococcus as new chassis for industrial biotechnology: biology, physiology and tools

Autor: F. Coze, P. Hivin, Assia Dreux-Zigha, J.-P. Leonetti, C. Lazarelli, G. Letellier, Pascale Joseph, R. Bernard, E. Gerber, S. Castang, Nicolas Chabot, E. Hauser, J. Olive

Publikováno v: Journal of Applied Microbiology

Deinococcus spp are among the most radiation-resistant micro-organisms that have been discovered. They show remarkable resistance to a range of damage caused by ionizing radiation, desiccation, UV radiation and oxidizing agents. Traditionally, Escher

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38127bba96c0014e3e078ad6d19aeaa4
https://doi.org/10.1111/jam.12808

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Fluorescent Probes of Tissue Transglutaminase Reveal Its Association with Arterial Stiffening

Autor: Pierre Moreau, Amina Mulani, Simon Moreau, Jeffrey W. Keillor, Nicolas Chabot

Publikováno v: Chemistry & Biology. 17(10):1143-1150

SummaryTissue transglutaminase (TG2) catalyzes the crosslinking of proteins. TG2 has been implicated in fibrosis and vascular calcification, both of which lead to a common feature of aging known as arterial stiffness. In order to probe the role of TG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92b770b13373d5da308719331b59ef3

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The bioorganic chemistry of transglutaminase — from mechanism to inhibition and engineering

Autor: Mari T. Kaartinen, William D. Lubell, Jeffrey W. Keillor, Yukiko Nakano, Joelle N. Pelletier, Emanuelle Fortin, Valerio Vinci, Christophe Pardin, Roberto A. Chica, Steve M.F.G. Gillet, Nicolas Chabot

Publikováno v: Canadian Journal of Chemistry. 86:271-276

Through a multidisciplinary approach comprising organic synthesis, molecular biology, and physical organic kinetic studies, we have studied the mechanism of transglutaminase-mediated transamidation. More recently, we have applied our understanding of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::39459971729d5835e5237fcf9781c464
https://doi.org/10.1139/v08-024

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Selective Irreversible Inhibition of Fructose 1,6-Bisphosphate Aldolase from Trypanosoma brucei

Autor: Casimir Blonski, Jurgen Sygusch, Mathieu Coincon, Paul A.M. Michels, Chantal Dax, Nicolas Chabot, Francis Duffieux

Publikováno v: Journal of Medicinal Chemistry. 49:1499-1502

An irreversible competitive inhibitor hydroxynaphthaldehyde phosphate was synthesized that is highly selective against the glycolytic enzyme fructose 1,6-bisphosphate aldolase from Trypanosoma brucei (causative agent of sleeping sickness). Inhibition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73562f8ad4350960c3b647279e3de1f7
https://doi.org/10.1021/jm050237b

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