Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Nicolas, Blondeau"'
Autor:
Veronika Brezani, Nicolas Blondeau, Jan Kotouček, Eva Klásková, Karel Šmejkal, Jan Hošek, Eliška Mašková, Pavel Kulich, Vilailak Prachyawarakorn, Catherine Heurteaux, Josef Mašek
Publikováno v:
ACS Omega, Vol 9, Iss 8, Pp 9027-9039 (2024)
Externí odkaz:
https://doaj.org/article/a9089187a0de442b8e1164542fa4ce4c
Autor:
S., Tauskela Joseph, Nicolas, Blondeau
Publikováno v:
Conditioning Medicine, 2018
Acute neuroprotection in numerous human clinical trials has been an abject failure. Major systemic-and procedural-based issues have subsequently been identified in both clinical trials and preclinical animal model experimentation. As well, issues rel
Externí odkaz:
http://arxiv.org/abs/1908.03332
Autor:
Thierry Coppola, Guillaume Daziano, Ilona Legroux, Sophie Béraud-Dufour, Nicolas Blondeau, Patricia Lebrun
Publikováno v:
Cells, Vol 12, Iss 23, p 2768 (2023)
Research in the field of pharmacology aims to generate new treatments for pathologies. Nowadays, there are an increased number of chronic disorders that severely and durably handicap many patients. Among the most widespread pathologies, obesity, whic
Externí odkaz:
https://doaj.org/article/70a557f00c384720b63c425ad556abff
Autor:
Michel Tauc, Marc Cougnon, Romain Carcy, Nicolas Melis, Thierry Hauet, Luc Pellerin, Nicolas Blondeau, Didier F. Pisani
Publikováno v:
Cell & Bioscience, Vol 11, Iss 1, Pp 1-23 (2021)
Abstract Since the demonstration of its involvement in cell proliferation, the eukaryotic initiation factor 5A (eIF5A) has been studied principally in relation to the development and progression of cancers in which the isoform A2 is mainly expressed.
Externí odkaz:
https://doaj.org/article/b37c878fff754435ae08d83cd4573bc1
Autor:
Marc Cougnon, Romain Carcy, Nicolas Melis, Isabelle Rubera, Christophe Duranton, Karine Dumas, Jean-François Tanti, Catherine Pons, Nicolas Soubeiran, Marina Shkreli, Thierry Hauet, Luc Pellerin, Sébastien Giraud, Nicolas Blondeau, Michel Tauc, Didier F. Pisani
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-14 (2021)
Abstract Inhibition of the eukaryotic initiation factor 5A activation by the spermidine analogue GC7 has been shown to protect proximal cells and whole kidneys against an acute episode of ischaemia. The highlighted mechanism involves a metabolic swit
Externí odkaz:
https://doaj.org/article/1c2ead5a19d749b38f91c58c3d62652c
Publikováno v:
Brain Circulation, Vol 3, Iss 2, Pp 78-86 (2017)
Brief periods of ischemia have been shown in many experimental setups to provide tolerance against ischemia in multiple organs including the brain, when administered before (preconditioning) or even after (postconditioning) the normally lethal ischem
Externí odkaz:
https://doaj.org/article/e449db876b624d24be9e63999fc41d00
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2019)
The pharmacological properties and physiological roles of the type I receptor sortilin, also called neurotensin receptor-3, are various and complex. Sortilin is involved in important biological functions from neurotensin and pro-Nerve Growth Factor s
Externí odkaz:
https://doaj.org/article/da4614af9b0a4e759338cba3f6c9021c
Autor:
Rossana Sirabella, Valeria Valsecchi, Serenella Anzilotti, Ornella Cuomo, Antonio Vinciguerra, Pasquale Cepparulo, Paola Brancaccio, Natascia Guida, Nicolas Blondeau, Lorella M. T. Canzoniero, Cristina Franco, Salvatore Amoroso, Lucio Annunziato, Giuseppe Pignataro
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Amyotrophic lateral sclerosis (ALS) is one of the most threatening neurodegenerative disease since it causes muscular paralysis for the loss of Motor Neurons in the spinal cord, brainstem and motor cortex. Up until now, no effective pharmacological t
Externí odkaz:
https://doaj.org/article/6ebd4e2ad47e4257bc7f4c4263b4c7eb
Autor:
Ophélia Le Thuc, Katharina Stobbe, Céline Cansell, Jean-Louis Nahon, Nicolas Blondeau, Carole Rovère
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
The hypothalamus is a key brain region in the regulation of energy balance as it controls food intake and both energy storage and expenditure through integration of humoral, neural, and nutrient-related signals and cues. Many years of research have f
Externí odkaz:
https://doaj.org/article/ee5bd97faf73437a9dff66f3b8f70227
Autor:
Nicolas Blondeau
Publikováno v:
médecine/sciences
médecine/sciences, EDP Sciences, 2021, 37 (6-7), pp.575-577. ⟨10.1051/medsci/2021068⟩
médecine/sciences, EDP Sciences, 2021, 37 (6-7), pp.575-577. ⟨10.1051/medsci/2021068⟩
International audience; No abstract available