Click-chemistry approach to study mycoloylated proteins: Evidence for PorB and PorC porins mycoloylation in Corynebacterium glutamicum.

Autor: Hanane Issa, Emilie Huc-Claustre, Thamila Reddad, Nolwenn Bonadé Bottino, Maryelle Tropis, Christine Houssin, Mamadou Daffé, Nicolas Bayan, Nathalie Dautin

Publikováno v: PLoS ONE, Vol 12, Iss 2, p e0171955 (2017)

Protein mycoloylation is a recently identified, new form of protein acylation. This post-translational modification consists in the covalent attachment of mycolic acids residues to serine. Mycolic acids are long chain, α-branched, β-hydroxylated fa

Externí odkaz: https://doaj.org/article/3c033673640d41239bbb1c8803b475cb

Synthesis of chemical tools to label the mycomembrane of corynebacteria using modified iron( iii ) chloride-mediated protection of trehalose

Autor: Mathieu Carlier, Emilie Lesur, Aurélie Baron, Aurélie Lemétais, Karine Guitot, Loïc Roupnel, Christiane Dietrich, Gilles Doisneau, Dominique Urban, Nicolas Bayan, Jean-Marie Beau, Dominique Guianvarc'h, Boris Vauzeilles, Yann Bourdreux

Publikováno v: Organic & Biomolecular Chemistry
Organic & Biomolecular Chemistry, 2022, 20 (9), pp.1974-1981. ⟨10.1039/D2OB00107A⟩

Trehalose-based probes are useful tools that allow the detection of the mycomembrane of mycobacteria through the metabolic labeling approach. Trehalose analogues conjugated to fluorescent probes can be used, and other probes are functionalized with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b5548bbcdb982416bdbbf7a2324001
https://hal.science/hal-03801948/document

S16 and T18 mannosylation sites of LppX are not essential for its activity in phthiocerol dimycocerosates localization at the surface of Mycobacterium tuberculosis

Autor: Laila Sago, Anna E. Grzegorzewicz, Michael R. McNeil, Mary Jackson, Cécile Labarre, Nicolas Bayan, Nathalie Dautin, Niloofar Mohiman

Publikováno v: Research in Microbiology
Research in Microbiology, Elsevier, In press, ⟨10.1016/j.resmic.2021.103874⟩
Research in Microbiology, In press, ⟨10.1016/j.resmic.2021.103874⟩

International audience; LppX is an important virulence factor essential for surface localization of phthiocerol dimycocerosates (DIM) in Mycobacterium tuberculosis. Based on Concanavalin A recognition, M. tuberculosis LppX (LppX-tb) was initially pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09cc78f0a5b873c451e6edf5813b3488
https://hal.archives-ouvertes.fr/hal-03389123

The ppm operon is essential for acylation and glycosylation of lipoproteins in Corynebacterium glutamicum.

Autor: Niloofar Mohiman, Manuela Argentini, Sarah M Batt, David Cornu, Muriel Masi, Lothar Eggeling, Gurdyal Besra, Nicolas Bayan

Publikováno v: PLoS ONE, Vol 7, Iss 9, p e46225 (2012)

BACKGROUND: Due to their contribution to bacterial virulence, lipoproteins and members of the lipoprotein biogenesis pathway represent potent drug targets. Following translocation across the inner membrane, lipoprotein precursors are acylated by lipo

Externí odkaz: https://doaj.org/article/1506c435413b441caf3c4a923ff39d4e

Architecture and Biogenesis of the Cell Envelope of Corynebacterium glutamicum

Autor: Nicolas Bayan, Christine Houssin, Cécile Labarre, Florence Constantinesco, Célia de Sousa d’Auria, Christiane Dietrich

Publikováno v: Corynebacterium glutamicum ISBN: 9783030392666

Corynebacteriales cells are surrounded by a multilayered cell envelope with unique architecture and composition. Corynebacterium glutamicum has become an increasingly used model to understand both biosynthesis and assembly of this complex compartment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc47a96562bbf517f7be14c285c257a7
https://doi.org/10.1007/978-3-030-39267-3_2