Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Nicolai S C, van Oers"'
Autor:
Alevtina Gall, Marita Bosticardo, Stacey Ma, Karin Chen, Kayla Amini, Francesca Pala, Ottavia M. Delmonte, Tara Wenger, Michael Bamshad, John Sleasman, Matthew Blessing, Nicolai S. C. van Oers, Luigi D. Notarangelo, M. Teresa de la Morena
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Pathogenic variants in the transcription factor TP63 are associated with clinically overlapping syndromes including ectrodactyly-ectodermal dysplasia clefting (EEC) and ankyloblepharon-ectodermal defects-cleft lip/palate (AEC). T cell lymphopenia has
Externí odkaz:
https://doaj.org/article/f3b40d2853fc4c849e9c6fd59b40708d
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The thymus, a primary lymphoid organ, produces the T cells of the immune system. Originating from the 3rd pharyngeal pouch during embryogenesis, this organ functions throughout life. Yet, thymopoiesis can be transiently or permanently damaged conting
Externí odkaz:
https://doaj.org/article/1b8e4e471cd241b5ad2572a247493047
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/bc4220e5283f4bd288dc3172a7fccf86
Autor:
Fatma S. Coskun, Shashikant Srivastava, Prithvi Raj, Igor Dozmorov, Serkan Belkaya, Smriti Mehra, Nadia A. Golden, Allison N. Bucsan, Moti L. Chapagain, Edward K. Wakeland, Deepak Kaushal, Tawanda Gumbo, Nicolai S. C. van Oers
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Nearly one third of the world’s population is infected with Mycobacterium tuberculosis (Mtb). While much work has focused on the role of different Mtb encoded proteins in pathogenesis, recent studies have revealed that Mtb also transcribes many non
Externí odkaz:
https://doaj.org/article/06e35103ef2d41e9bd53d7eb9f6e5990
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
22q11.2 deletion syndrome (DiGeorge), CHARGE syndrome, Nude/SCID and otofaciocervical syndrome type 2 (OTFCS2) are distinct clinical conditions in humans that can result in hypoplasia and occasionally, aplasia of the thymus. Thymic hypoplasia/aplasia
Externí odkaz:
https://doaj.org/article/297198f1551f40879076faf12e45cd72
Publikováno v:
Frontiers in Genetics, Vol 10 (2020)
Chromosome 22q11.2 deletion syndrome (22q11.2del) is a complex, multi-organ disorder noted for its varying severity and penetrance among those affected. The clinical problems comprise congenital malformations; cardiac problems including outflow tract
Externí odkaz:
https://doaj.org/article/a08679cba340473f9ae0392ac7cf4a0a
Publikováno v:
Non-Coding RNA, Vol 7, Iss 4, p 69 (2021)
Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb), with 10.4 million new cases per year reported in the human population. Recent studies on the Mtb transcriptome have revealed the abundance of noncoding RNAs expres
Externí odkaz:
https://doaj.org/article/a1ccabb8a6804255bdad81a912b92160
Autor:
Nicolai S. C. van Oers, Igor Dozmorov, Rebecca S. Gruchalla, Quan Zhen Li, Patricia Pichilingue-Reto, M. Teresa de la Morena, Prithvi Raj, Edward K. Wakeland, Morgan Nelson, David R. Karp
Publikováno v:
Journal of Clinical Immunology
Purpose The human antibody repertoire forms in response to infections, the microbiome, vaccinations, and environmental exposures. The specificity of such antibody responses was compared among a cohort of toddlers to identify differences between serop
Autor:
Dana A. Dodd, Randall G. Worth, Michael K. Rosen, Sergio Grinstein, Nicolai S. C. van Oers, Eric J. Hansen
Publikováno v:
mBio, Vol 5, Iss 3 (2014)
ABSTRACT Haemophilus ducreyi causes chancroid, a sexually transmitted infection. A primary means by which this pathogen causes disease involves eluding phagocytosis; however, the molecular basis for this escape mechanism has been poorly understood. H
Externí odkaz:
https://doaj.org/article/ac803788f8fe4332a2c7c53ed344a1c5
Autor:
Serkan Belkaya, Nicolai S C van Oers
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85274 (2014)
Physiological stress resulting from infections, trauma, surgery, alcoholism, malnutrition, and/or pregnancy results in a substantial depletion of immature CD4(+)CD8(+) thymocytes. We previously identified 18 distinct stress-responsive microRNAs (miRs
Externí odkaz:
https://doaj.org/article/8c9bfce2c562461a8c150b21c7cc9eb5