Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nicolai Maas"'
Autor:
Christoph Rogmans, Jan Dittrich, Emily Hamm, Jörg Paul Weimer, David Holthaus, Norbert Arnold, Inken Flörkemeier, Nicolai Maass, Peer Jansen, Astrid Dempfle, Dirk O. Bauerschlag, Nina Hedemann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Acquired or de novo resistance to poly (ADP-ribose) polymerase inhibitors (PARPi) is a major challenge to ovarian cancer treatment. Therefore, strategies to overcome PARPi resistance are critical to improve prognosis. The purpose of this stu
Externí odkaz:
https://doaj.org/article/4291c4464e794268896575de7315d9cc
Autor:
Inken Flörkemeier, Lisa K. Antons, Jörg P. Weimer, Nina Hedemann, Christoph Rogmans, Sandra Krüger, Regina Scherließ, Astrid Dempfle, Norbert Arnold, Nicolai Maass, Dirk O. Bauerschlag
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract In vitro, spheroid models have become well established in cancer research because they can better mimic certain characteristics of in vivo tumours. However, interaction with the tumour microenvironment, such as cancer-associated fibroblasts,
Externí odkaz:
https://doaj.org/article/64babe67f1b14d97a499efdf4b30fa15
Inhibition of ADAM17 increases the cytotoxic effect of cisplatin in cervical spheroids and organoids
Autor:
David Holthaus, Christoph Rogmans, Ina Gursinski, Alvaro Quevedo-Olmos, Marzieh Ehsani, Mandy Mangler, Inken Flörkemeier, Jörg P. Weimer, Thomas F. Meyer, Nicolai Maass, Dirk O. Bauerschlag, Nina Hedemann
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
IntroductionCervical cancer represents one of the main causes of female, cancer-related mortality worldwide. The majority of cancers are caused by human papillomaviruses such as HPV16 and HPV18. As chemotherapeutic resistance to first-line platinum t
Externí odkaz:
https://doaj.org/article/03b213b6b8984864bcfc1799a85cfa7e
Autor:
Melanie Schubert, Anastasia Tihon, Kristin Andresen, Zino Ruchay, André Farrokh, Nicolai Maass, Philipp Elischer, Ann Carolin Longardt, Karolin Tesch, Annett Lebenatus, Magret Krüger, Ibrahim Alkatout
Publikováno v:
Journal of Medical Case Reports, Vol 18, Iss 1, Pp 1-10 (2024)
Abstract Introduction The management of a pregnancy in a bicornuate uterus is particularly challenging. A bicornuate uterus is a rare occurrence and a twin pregnancy in a bicornuate uterus even more rare. These pregnancies call for intensive diagnost
Externí odkaz:
https://doaj.org/article/3907d24bb6ac4398b8b2bda3f7f8b287
Publikováno v:
Der Gynäkologe. 52:354-359
Mehr als zwei Drittel der neu diagnostizierten Brustkrebserkrankungen sind hormonabhangige Tumoren. Als Standard bei pramenopausalen Patientinnen galt lange die 5‑jahrige adjuvante Therapie mit Tamoxifen und bei postmenopausalen Patientinnen mit ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e7d71d5dd9e0896d487f2af510a373a
https://doi.org/10.1007/s00129-019-4426-6
https://doi.org/10.1007/s00129-019-4426-6
Autor:
Amelie Limburg, Xueqian Qian, Bernice Brechtefeld, Nina Hedemann, Inken Flörkemeier, Christoph Rogmans, Leticia Oliveira-Ferrer, Nicolai Maass, Norbert Arnold, Dirk O. Bauerschlag, Jörg Paul Weimer
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1171 (2024)
Examinations of ovarian cancer cells require the ability to identify tumor cells. Array-based comparative genome hybridization (aCGH) on 30 ovarian carcinomas (OC) identified three genomic loci (8q24.23; 17p12; 18q22.3) over- or under-represented in
Externí odkaz:
https://doaj.org/article/8d8eff3e1e8741f2b322bb36731c4e4b
Autor:
Gerrit Hugendieck, Marcus Lettau, Svenja Andreas, Sabrina Neumann, Natalie Reinhardt, Philipp Arnold, Franziska Theilig, Lorenz Bastian, Christoph Rogmans, Jörg P. Weimer, Inken Flörkemeier, Daniela Wesch, Norbert Arnold, Nicolai Maass, Ottmar Janssen, Dirk Bauerschlag, Nina Hedemann
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 7, Pp n/a-n/a (2023)
Abstract Ovarian cancer (OvCa) is the gynaecological disorder with the poorest prognosis due to the fast development of chemoresistance. We sought to connect chemoresistance and cancer cell‐derived extracellular vesicles (EV). The mechanisms of how
Externí odkaz:
https://doaj.org/article/b608a4f57c4247b186f7a69bb4075f92
Autor:
Johannes Ackermann, Julian Pape, Felix Vogler, Julia Pahls, Jorun Baumann, Bernd Holthaus, Günter Karl Noé, Michael Anapolski, Zino Ruchay, Anna Westermann, Veronika Günther, Kristin Andresen, Leila Allahqoli, Gaby Moawad, Jörg Neymeyer, Sandra Brügge, Nicolai Maass, Liselotte Mettler, Ibrahim Alkatout
Publikováno v:
Medicina, Vol 60, Iss 1, p 159 (2024)
Background and Objectives: The acquisition of practical skills at medical school is an important part of the multidimensional education program of future physicians. However, medical schools throughout the world have been slow in incorporating practi
Externí odkaz:
https://doaj.org/article/a82bbcd147bc4c37a43b2eb5379b4e49
Publikováno v:
Medicina, Vol 60, Iss 1, p 53 (2023)
Minimally invasive surgery (MIS) in gynecology was introduced to achieve the same surgical objectives as traditional open surgery while minimizing trauma to surrounding tissues, reducing pain, accelerating recovery, and improving overall patient outc
Externí odkaz:
https://doaj.org/article/ac9270987f8141688a877cdbb296e0e6
Autor:
Stella Juliane Vieth, MSc, Jamie Hartmann-Boyce, MA, DPhil, Nicolai Maass, MD, PhD, Anant Jani, PhD
Publikováno v:
AJOG Global Reports, Vol 2, Iss 4, Pp 100119- (2022)
BACKGROUND: In Germany, we see a decline in the use of the oral contraceptive pill. Although there have been studies showing a lack of knowledge about the mode of action of the pill and alternative methods, the number of German women who feel well in
Externí odkaz:
https://doaj.org/article/74dc32d40ed84dcfa29520bf848de8c2