Výsledky vyhledávání - "Nicolai Brill"

A multi-purpose force-controlled loading device for cartilage and meniscus functionality assessment using advanced MRI techniques

Autor: Johannes Thüring, Benedikt J. Braun, Nicolai Brill, Sven Nebelung, Dorit Merhof, Daniel Truhn, Christiane K. Kuhl, Matthias Knobe

Publikováno v: Journal of the Mechanical Behavior of Biomedical Materials. 101:103428

A bstract Response to loading of soft tissues as assessed by advanced magnetic resonance imaging (MRI) techniques is a promising approach to evaluate tissue functionality beyond (statically obtained) structural and compositional features. As cartilag

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f8984db31e0953b66b289e7f3ebbc0
https://doi.org/10.1016/j.jmbbm.2019.103428

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Detecting early stage osteoarthritis by optical coherence tomography?

Autor: Nicolai Brill, Holger Jahr, Sven Nebelung

Publikováno v: Biomarkers : biochemical indicators of exposure, response, and susceptibility 20(8), 590-596 (2015). doi:10.3109/1354750X.2015.1130190 special issue: "Arthritis Biomarkers"
Biomarkers

Osteoarthritis (OA) is the most common chronic disease of our joints, manifested by a dynamically increasing degeneration of hyaline articular cartilage (AC). While currently no therapy can reverse this process, the few available treatment options ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46dfa83d7f90bc47fcb69b7febe5cddb
https://doi.org/10.3109/1354750x.2015.1130190

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Three-dimensional imaging and analysis of human cartilage degeneration using Optical Coherence Tomography

Autor: Markus Tingart, Robert Schmitt, Björn Rath, Nicolai Brill, Valentin Quack, Sven Nebelung, Ulrich Marx, Holger Jahr

Publikováno v: Journal of Orthopaedic Research. 33:651-659

Optical Coherence Tomography (OCT) is an evolving imaging technology allowing non-destructive imaging of cartilage tissue at near-histological resolution. This study investigated the diagnostic value of real time 3-D OCT in comparison to conventional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a48f248a4c16a254ac8dfc41d6e49b7
https://doi.org/10.1002/jor.22828

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Evaluation of Single-Impact-Induced Cartilage Degeneration by Optical Coherence Tomography

Autor: Markus Tingart, Sven Nebelung, Björn Rath, Robert Schmitt, Thomas Pufe, Nicolai Brill, Florence de Bont, Holger Jahr

Publikováno v: BioMed Research International, Vol 2015 (2015)
BioMed Research International
BioMed research international 2015, 486794 (2015). doi:10.1155/2015/486794

Posttraumatic osteoarthritis constitutes a major cause of disability in our increasingly elderly population. Unfortunately, current imaging modalities are too insensitive to detect early degenerative changes of this disease. Optical coherence tomogra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::990d6e6b859772d93cdf1e5164ba09bc
https://doi.org/10.1155/2015/486794

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Quantitative articular cartilage sub-surface defect assessment using optical coherence tomography: An in-vitro study

Autor: Markus Tingart, Matthias Knobe, Roman Michalik, Sven Nebelung, Thorn Pauer, Nicolai Brill, Holger Jahr, Daniel Truhn

Publikováno v: Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft. 221

Assessment of structural cartilage damage is of high scientific and clinical interest. Optical Coherence Tomography (OCT) is a light-based cross-sectional imaging modality that allows the real-time assessment of articular cartilage at near-histologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17057687f7451db61a28249f8bf6b2f2
https://pubmed.ncbi.nlm.nih.gov/30312767

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Morphometric grading of osteoarthritis by optical coherence tomography - An ex vivo study

Autor: Ulrich Marx, Sven Nebelung, Marcus Stoffel, Valentin Quack, Nicolai Brill, Robert Schmitt, Markus Tingart, Bei Zhou, Darius Arbab, Björn Rath, Holger Jahr

Publikováno v: Journal of Orthopaedic Research. 32:1381-1388

Optical Coherence Tomography (OCT) yields microscopic cross-sectional images of cartilage in real time and at high resolution. As yet, comprehensive grading of degenerative cartilage changes based on OCT has rarely been performed. This study investig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bdb4779316b974b56aaaedf2464ccf3f
https://doi.org/10.1002/jor.22673

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Towards optical coherence tomography-based elastographic evaluation of human cartilage

Autor: Felix Müller, Thomas Pufe, Robert Schmitt, Dorit Merhof, Nicolai Brill, Sven Nebelung, Daniel Truhn, Markus Tingart, Holger Jahr

Optical Coherence Tomography (OCT) is an imaging technique that allows the surface and subsurface evaluation of semitransparent tissues by generating microscopic cross-sectional images in real time, to millimetre depths and at micrometre resolutions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb6b455f5b70edfecdba6d7f55c7687
https://publica.fraunhofer.de/handle/publica/244828

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High-speed microscopy of continuously moving cell culture vessels

Autor: Robert Schmitt, Friedrich Schenk, Ulrich Marx, Daniel Hardt, Nicolai Brill, Niels König

Publikováno v: Scientific reports 6, 34038 (2016). doi:10.1038/srep34038
Scientific Reports

Scientific reports 6, 34038 (2016). doi:10.1038/srep34038
Published by Nature Publishing Group, London

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e49c5bfba0fb827d81fac3009380ad9
https://publications.rwth-aachen.de/record/674428

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Quantitative OCT and MRI biomarkers for the differentiation of cartilage degeneration

Autor: Daniel Truhn, Thomas Pufe, Markus Tingart, Nicolai Brill, Sven Nebelung, Christiane K. Kuhl, Holger Jahr

Objective To evaluate the usefulness of quantitative parameters obtained by optical coherence tomography (OCT) and magnetic resonance imaging (MRI) in the comprehensive assessment of human articular cartilage degeneration. Materials and methods Human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a50068340bc300919594c100420dd30
https://publica.fraunhofer.de/handle/publica/244753

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Polarization-sensitive optical coherence tomography-based imaging, parameterization, and quantification of human cartilage degeneration

Autor: Robert Schmitt, Mathias Wirtz, Markus Tingart, Holger Jahr, Nicolai Brill, Sven Nebelung, Daniel Truhn, Dorit Merhof

Polarization-sensitive optical coherence tomography (PS-OCT) is a light-based, high-resolution, real-time, noninvasive, and nondestructive imaging modality yielding quasimicroscopic cross-sectional images of cartilage. As yet, comprehensive parameter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0317a54cc4b149d1f91b96e733c11f20
https://publica.fraunhofer.de/handle/publica/246350

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