Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicolai A. Kittan"'
Autor:
Nicolai A Kittan, Ronald M Allen, Abhay Dhaliwal, Karen A Cavassani, Matthew Schaller, Katherine A Gallagher, William F Carson, Sumanta Mukherjee, Jolanta Grembecka, Tomasz Cierpicki, Gabor Jarai, John Westwick, Steven L Kunkel, Cory M Hogaboam
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e78045 (2013)
Macrophages (MΦ) play an essential role in innate immune responses and can either display a pro-inflammatory, classically activated phenotype (M1) or undergo an alternative activation program (M2) promoting immune regulation. M-CSF is used to differ
Externí odkaz:
https://doaj.org/article/aa82d74e1bf24ffa9f824ede7abb0d9b
Autor:
Megan Elfline, Ronald M. Allen, Steven L. Kunkel, Nicolai A. Kittan, Carson Oostra, Osama M. El-Sayed, Cory M. Hogaboam, Peter K. Henke, Anthony J. Comerota, Nicholas A. Dewyer, Catherine E. Luke, Adriana Laser
Publikováno v:
Thrombosis and Haemostasis. 114:1028-1037
SummaryDeep-vein thrombosis (DVT) resolves via a sterile inflammatory response. Defining the inflammatory response of DVT may allow for new therapies that do not involve anticoagulation. Previously, we have shown that Toll-like receptor 9 (Tlr9) gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc638c510dae1fa4a44119770fd539c
https://doi.org/10.1160/th14-12-1031
https://doi.org/10.1160/th14-12-1031
Autor:
Sumanta Mukherjee, Steven L. Kunkel, Ivan Maillard, Philaretos C. Kousis, Cynthia J. Guidos, Paul E. Kowalski, Andrew J. Rasky, Phil A. Lundy, Nicholas W. Lukacs, Nicolai A. Kittan
Publikováno v:
The Journal of Immunology. 192:996-1003
Notch activation plays an important role in T cell development and mature T cell differentiation. In this study, we investigated the role of Notch activation in a mouse model of respiratory syncytial virus (RSV)–exacerbated allergic airway disease.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0af1221454c294c203a363faccdf5f25
https://doi.org/10.4049/jimmunol.1301991
https://doi.org/10.4049/jimmunol.1301991
Autor:
Stefan W. Krause, Fabian Beier, Gerhard C. Hildebrandt, Ernst Holler, Nicolai A. Kittan, Reinhard Andreesen, Klaus Arbter
Publikováno v:
Molecular and Clinical Oncology. 2:81-86
Eosinophilia after allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been associated with the development of acute and chronic graft-versus-host disease (cGVHD). However, a limited number of studies have investigated the course of eo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de023ecf15601d194f9d607a7c52d860
https://doi.org/10.3892/mco.2013.192
https://doi.org/10.3892/mco.2013.192
Autor:
Amrita Joshi, William F. Carson, Steven L. Kunkel, Katherine A. Gallagher, Craig N. Johnson, David M. Aronoff, Matthew Schaller, Karen A. Cavassani, Elyara M. Soares, Yali Dou, Melissa Scola, Akihiro Matsukawa, Nicolai A. Kittan, Soichiro Hirai
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(5)
Macrophages are critical immune cells for the clearance of microbial pathogens and cellular debris from peripheral tissues. Macrophage inflammatory responses are governed by gene expression patterns, and these patterns are often subject to epigenetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dc5aeea3a21448addcda4cba882506d
https://pubmed.ncbi.nlm.nih.gov/28733487
https://pubmed.ncbi.nlm.nih.gov/28733487
Autor:
Nicolai A. Kittan, Andreas Ramming, Rita Weinkam, Christina Bergmann, Georg Schett, Jörg H W Distler, Christiane Maier, Christian Beyer
Publikováno v:
Annals of the rheumatic diseases. 76(6)
ObjectivesTo investigate the disease-modifying effects of phosphodiesterase 4 (PDE4) inhibition in preclinical models of systemic sclerosis (SSc).MethodsWe studied the effects of PDE4 inhibition in a prevention and a treatment model of bleomycin-indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b59ce9b2f101d1e09259f7354d6be7
https://pubmed.ncbi.nlm.nih.gov/28275263
https://pubmed.ncbi.nlm.nih.gov/28275263
Autor:
Stefan Pöhlmann, Sabrina Haupt, Norbert Bannert, Elke Bogner, Klaus Korn, Gudrun Holland, Barbara Schmidt, Moritz Ries, Norbert Donhauser, Nicolai A. Kittan, Kathrin Pritschet, Philipp Schuster
Publikováno v:
Virology. 423(2):152-164
Chronic immune activation, triggered by plasmacytoid dendritic cell (PDC) interferon (IFN)-alpha production, plays an important role in HIV-1 pathogenesis. As the entry of HIV-1 seems to be important for the activation of PDC, we directly characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bc7d1e7db5d4c19b58295d691d88569
Autor:
Tomasz Cierpicki, Karen A. Cavassani, Jolanta Grembecka, Steven L. Kunkel, Danielle N. Kroetz, William F. Carson, Matthew Schaller, Nicolai A. Kittan, Catherine Ptaschinski, Ronald M. Allen, Nuria Godessart, Yali Dou, Toshihiro Ito
It is well established that the cytokine IL-12 and the transcription factor STAT4, an essential part of the IL-12 signaling pathway, are critical components of the Th1 differentiation process in T cells. In response to pathogenic stimuli, this proces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a9b796206a8ebf6d3ccd168231cfba5
https://europepmc.org/articles/PMC4763868/
https://europepmc.org/articles/PMC4763868/
Autor:
Elena Spacenko, Gerhard C. Hildebrandt, Max Hager, Sandra Miklos, Fridrik Karlsson, Sabarinath Venniyil Radhakrishnan, Nicolai A. Kittan, Elisabeth Huber, Gunnar Mueller, Senthilnathan Palaniyandi
Publikováno v:
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation. 21(1)
Noninfectious lung injury and acute graft-versus-host disease (GVHD) after allogeneic hematopoietic cell transplantation (allo-HCT) are associated with significant morbidity and mortality. Azithromycin is widely used in allogeneic HCT recipients for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ecae6f72ef5d119707788ed1096c97e
https://pubmed.ncbi.nlm.nih.gov/25445642
https://pubmed.ncbi.nlm.nih.gov/25445642
Publikováno v:
Current osteoporosis reports. 12(1)
In rheumatoid arthritis (RA), the presence of autoantibodies such as the rheumatoid factor and antibodies against citrullinated proteins is highly correlated with the severity of disease and bone loss. For many years, the involvement of autoantibodie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc382d5bca9152d7af6e9443eea73fd5
https://pubmed.ncbi.nlm.nih.gov/24407713
https://pubmed.ncbi.nlm.nih.gov/24407713