Assessing Glycosphingolipid Profiles in Human Health and Disease Using Non-Imaging MALDI Mass Spectrometry

Autor: Cristina Ramona Novaconi, Robert Onulov, Alina Florina Serb, Eugen Sisu, Nicolae Dinca, Mihai-Cosmin Pascariu, Marius Georgescu

Publikováno v: Applied Sciences, Vol 13, Iss 17, p 9922 (2023)

Glycosphingolipids (GSLs) are a glycolipid subtype which plays vital roles in numerous biological processes, cell–cell interactions, as well as oncogenesis and ontogenesis. They are ubiquitous molecules found mostly in cell membranes. Abnormal expr

Externí odkaz: https://doaj.org/article/f0b9defb509f43bab7d809abb0f6904e

Computed Mass-Fragmentation Energy Profiles of Some Acetalized Monosaccharides for Identification in Mass Spectrometry

Autor: Mihai-Cosmin Pascariu, Nicolae Dinca, Carolina Cojocariu, Eugen Sisu, Alina Serb, Romina Birza, Marius Georgescu

Publikováno v: Symmetry, Vol 14, Iss 5, p 1074 (2022)

Our study found that quantum calculations can differentiate fragmentation energies into isomeric structures with asymmetric carbon atoms, such as those of acetalized monosaccharides. It was justified by the good results that have been published in re

Externí odkaz: https://doaj.org/article/99b5b4a0308c44668e44350febe6b1cb

Structural identification by differential mass spectrometry as a criterion for selecting the best quantum chemical calculation of formation enthalpy for tetrachlorinated biphenyls

Autor: Adrian Covaci, Nicolae Dinca

Publikováno v: Rapid Communications in Mass Spectrometry. 26:2033-2040

RATIONALE The assignment of correct structures for isomers with similar mass spectra (e.g. polyhalogenated aromatic compounds) is not always successful when spectral libraries alone are employed or, even worse, when the compounds are not present in c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cfcebda0e04a8fc66e0b3b3d39452654
https://doi.org/10.1002/rcm.6321

Synthesis and structural characterization of amino-functionalized polysaccharides

Autor: Sorin Tudor, Corina Flangea, Alina D. Zamfir, Lucian Mircea Rusnac, Nicolae Dinca, Ioana Sisu, Eugen Sisu, Valentina Udrescu

Publikováno v: Open Chemistry, Vol 7, Iss 1, Pp 66-73 (2009)

A variety of carbohydrates, in particular polysaccharides can be subjected to chemical modification to obtain derivatives with amphiphilic properties, which enable biochemical or biological reactions at the polymer surface. In the present work, a pol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49acc1c0b0ae0cd5114a8957100ca4f0
https://doi.org/10.2478/s11532-008-0090-8

Synthesis and stereochemistry of some new 1,3,5-tris(1,3-dioxan-2-yl)-benzene derivatives

Autor: Gérard Plé, Yvan Ramondenc, Anamaria Terec, Ion Grosu, Monica Cîrcu, Loïc Toupet, Nicolae Dinca, Maria Carmen Florian

Publikováno v: Open Chemistry, Vol 4, Iss 4, Pp 808-821 (2006)
Central European Journal of Chemistry
Central European Journal of Chemistry, Springer Verlag, 2006, 4 (4), pp.808-821. ⟨10.2478/s11532-006-0040-2⟩
Central European Journal of Chemistry, 2006, 4 (4), pp.808-821. ⟨10.2478/s11532-006-0040-2⟩

The synthesis and the stereochemistry of new 1,3,5-tris(1,3-dioxan-2-yl)-benzene derivatives are reported. The anancomeric structure and the axial orientation of the aryl group with respect to all 1,3-dioxane rings, and the cis-trans isomerism of som

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9563f1b7f5f141dc88cd410c3fa7606
https://doaj.org/article/6daddd4c995a4c51bb6b9ba89f6a796f