Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Nicolae Adrian, Leu"'
Autor:
Kylie D. Rock, Lillian M. Folts, Hannah C. Zierden, Ruth Marx-Rattner, Nicolae Adrian Leu, Bridget M. Nugent, Tracy L. Bale
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract The genetic material encoded on X and Y chromosomes provides the foundation by which biological sex differences are established. Epigenetic regulators expressed on these sex chromosomes, including Kdm6a (Utx), Kdm5c, and Ddx3x have far-reach
Externí odkaz:
https://doaj.org/article/63a5818c04144b3ab6baa3941d366929
Autor:
Suhee Chang, Diana Fulmer, Stella K Hur, Joanne L Thorvaldsen, Li Li, Yemin Lan, Eric A Rhon-Calderon, Nicolae Adrian Leu, Xiaowen Chen, Jonathan A Epstein, Marisa S Bartolomei
Publikováno v:
eLife, Vol 11 (2022)
Dysregulation of the imprinted H19/IGF2 locus can lead to Silver-Russell syndrome (SRS) in humans. However, the mechanism of how abnormal H19/IGF2 expression contributes to various SRS phenotypes remains unclear, largely due to incomplete understandi
Externí odkaz:
https://doaj.org/article/6e1ce1ff28534687a37e77cf4367e911
Autor:
Kylie D. Rock, Lillian Folts, Hannah C. Zierden, Ruth Marx-Rattner, Nicolae Adrian Leu, Bridget M. Nugent, Tracy L. Bale
The genetic material encoded on X and Y chromosomes provides the foundation by which biological sex differences are established. Epigenetic regulators expressed on these sex chromosomes, including Kdm6a (Utx), Kdm5c, and Ddx3x have far-reaching impac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf67000ae0a6b46dcdfd72596fa764ff
https://doi.org/10.21203/rs.3.rs-2928137/v1
https://doi.org/10.21203/rs.3.rs-2928137/v1
Autor:
Pavan Vedula, Satoshi Kurosaka, Nicolae Adrian Leu, Yuri I Wolf, Svetlana A Shabalina, Junling Wang, Stephanie Sterling, Dawei W Dong, Anna Kashina
Publikováno v:
eLife, Vol 6 (2017)
β‐ and γ‐cytoplasmic actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes that play non‐redundant biological roles. The key determinants that drive their functional distinction are unknown. Here,
Externí odkaz:
https://doaj.org/article/07d6201b1b754dc09370bbeb3e8182bd
Autor:
Suhee Chang, Diana Fulmer, Stella K Hur, Joanne L Thorvaldsen, Li Li, Yemin Lan, Eric A Rhon-Calderon, Nicolae Adrian Leu, Xiaowen Chen, Jonathan A Epstein, Marisa S Bartolomei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2486457cd9cb1cb518bad21f891e224
https://doi.org/10.7554/elife.78754.sa2
https://doi.org/10.7554/elife.78754.sa2
Autor:
Ryan James Cedeno, Angela Nakauka-Ddamba, Maryam Yousefi, Stephanie Sterling, Nicolae Adrian Leu, Ning Li, John R Pehrson, Christopher Joachim Lengner
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185196 (2017)
A stem cell's epigenome directs cell fate during development, homeostasis, and regeneration. Epigenetic dysregulation can lead to inappropriate cell fate decisions, aberrant cell function, and even cancer. The histone variant macroH2A has been shown
Externí odkaz:
https://doaj.org/article/ca70c7c3afb647479940f645146dc903
Autor:
Suhee, Chang, Diana, Fulmer, Stella K, Hur, Joanne L, Thorvaldsen, Li, Li, Yemin, Lan, Eric A, Rhon-Calderon, Nicolae Adrian, Leu, Xiaowen, Chen, Jonathan A, Epstein, Marisa S, Bartolomei
Publikováno v:
eLife. 11
Dysregulation of the imprinted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fa8b68d926269779393023bf2939c7b
https://pubmed.ncbi.nlm.nih.gov/36441651
https://pubmed.ncbi.nlm.nih.gov/36441651
Autor:
Zvi Cramer, Xin Wang, Nicolae Adrian Leu, Keara Monaghan, Joshua H. Rhoades, Yuhua Tian, Joshua Rico, Diego Mendez, Ricardo Petroni, Melissa S. Kim, Ning Li, Christopher J. Lengner, M. Andres Blanco
Publikováno v:
Cancer Research. 82:PR004-PR004
Colorectal cancer (CRC) is the 2nd-leading cause of cancer-related deaths worldwide and metastatic disease remains a major unmet clinical need. Nevertheless, the molecular underpinnings of metastatic spread and colonization of distant sites remain el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bafa33aadbb71a26d8371b7b7abb31c3
https://doi.org/10.1158/1538-7445.crc22-pr004
https://doi.org/10.1158/1538-7445.crc22-pr004
Autor:
Nicolae Adrian Leu, Darya A. Tourzani, Maria Gracia Gervasi, Jingshu Wang, Pablo E. Visconti, Gordon Ruthel, Fan Nils Yang
SummaryThe CatSper cation channel is essential for sperm capacitation and male fertility. The multi-subunit CatSper complexes form highly organized calcium signaling nanodomains on flagellar membranes. Here we report identification of an uncharacteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53c43a4ade6c8fc0b4ec3d98ae633d93
https://doi.org/10.1101/2021.07.06.451342
https://doi.org/10.1101/2021.07.06.451342
Autor:
Snahlata Singh, Emily Elenio, Rose-Anne Romano, Nicolae Adrian Leu, Andrew E. Vaughan, Rumela Chakrabarti, Jennifer deRiso, Kameswaran Surendran
Publikováno v:
FEBS Letters. 593:1030-1039
Elf5 is a transcription factor known to regulate critical developmental processes and has been shown to act as a tumour suppressor in multiple cancers. Elf5 knockout mice are embryonically lethal, limiting in vivo studies pertaining to its function.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f474b399ad44b3ba5d2a2232dc991001
https://doi.org/10.1002/1873-3468.13390
https://doi.org/10.1002/1873-3468.13390