Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Nicolaas J. H. Raat"'
Autor:
Rinse Ubbink, Lucia W. J. M. Streng, Nicolaas J. H. Raat, Floor A. Harms, Peter A. W. te Boekhorst, Robert J. Stolker, Egbert G. Mik
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 1873 (2023)
In light of the associated risks, the question has been raised whether the decision to give a blood transfusion should solely be based on the hemoglobin level. As mitochondria are the final destination of oxygen transport, mitochondrial parameters ar
Externí odkaz:
https://doaj.org/article/5a42e3e2173b4609b07f568528588d43
Autor:
Lucia W. J. M. Streng, Calvin J. de Wijs, Nicolaas J. H. Raat, Patricia A. C. Specht, Dimitri Sneiders, Mariëlle van der Kaaij, Henrik Endeman, Egbert G. Mik, Floor A. Harms
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1746 (2022)
Mitochondrial dysfunction has been linked to disease progression in COVID-19 patients. This observational pilot study aimed to assess mitochondrial function in COVID-19 patients at intensive care unit (ICU) admission (T1), seven days thereafter (T2),
Externí odkaz:
https://doaj.org/article/07faa7a82c2a48b897ae3563c48de6cc
Autor:
Mik, Rinse Ubbink, Lucia W. J. M. Streng, Nicolaas J. H. Raat, Floor A. Harms, Peter A. W. te Boekhorst, Robert J. Stolker, Egbert G.
Publikováno v:
Biomedicines; Volume 11; Issue 7; Pages: 1873
In light of the associated risks, the question has been raised whether the decision to give a blood transfusion should solely be based on the hemoglobin level. As mitochondria are the final destination of oxygen transport, mitochondrial parameters ar
Autor:
Ido J. Bontekoe, Pieter F. van der Meer, Bea C. Tanis, Dirk de Korte, Arthur J. Verhoeven, Nicolaas J. H. Raat, Patricia A. C. Specht, Egbert G. Mik, Thomas R. L. Klei
Publikováno v:
Transfusion, 62(12), 2609-2620. Wiley-Blackwell
Transfusion, 62(12), 2609-2620. Wiley-Blackwell Publishing Ltd
Transfusion, 62(12), 2609-2620. Wiley-Blackwell Publishing Ltd
Background: Platelets (PLTs) differ in glycolytic activity, resulting in rapid acidification of ‘poor’ storing PLT concentrates (PCs) in plasma, or depletion of glucose when stored in PLT additive solution (PAS). We aimed to understand why PLT gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc4cfe5739615df052c2b6be9d78eb3
https://pure.amc.nl/en/publications/donor-variation-in-stored-platelets(373fa33b-9d1e-4c62-aa1a-96bed337ce47).html
https://pure.amc.nl/en/publications/donor-variation-in-stored-platelets(373fa33b-9d1e-4c62-aa1a-96bed337ce47).html
Autor:
Egbert G. Mik, Nathalie Dollee, G.C. Schoonderwoerd, Nicolaas J. H. Raat, Mark A. Wefers Bettink, Floor A. Harms, Patricia A.C. Specht
Publikováno v:
Mitochondrion, 50, 149-157. Elsevier
Mitochondrial function has been predominantly measured ex vivo. Due to isolation and preservation procedures ex vivo measurements might misrepresent in vivo mitochondrial conditions. Direct measurement of in vivo mitochondrial oxygen tension (mitoPO2
Autor:
Marieke van der Heijde-Mulder, Changbo Qu, Qiuwei Pan, Mohamad S. Hakim, Ehsan Shokrollahi, Nicolaas J. H. Raat, Meng Li, Maikel P. Peppelenbosch, Yijin Wang, Shaoshi Zhang, Wenshi Wang
Publikováno v:
FASEB Journal, 33(1), 1008-1019. FASEB
Hepatitis E virus (HEV) infection has emerged as a global health problem. However, no approved medication is available, and the infection biology remains largely elusive. Electron transport chain (ETC), a key component of the mitochondria, is the mai
Publikováno v:
Journal of Emergency and Critical Care Medicine. 3:45-45
Safeguarding an adequate oxygen transport to organs and tissues is a prime goal in the care for critically ill patients. Over the last two decades it has become clear that in certain pathophysiological circumstances macrocirculatory derailment is fol
Autor:
Christine C. Helms, Landon Bellavia, Gabriela A. Ferreyra, Alan N. Schechter, Junfeng Sun, Steven B. Solomon, Steven J. Kern, Daniel A. Sweeney, Linda C. McPhail, Mark T. Gladwin, Charles Natanson, Andreas Perlegas, Barbora Piknova, S. Bruce King, Nicolaas J. H. Raat, Daniel B. Kim-Shapiro
Publikováno v:
Free Radical Biology and Medicine. 53:2229-2239
Plasma hemoglobin (Hb) released during intravascular hemolysis has been associated with numerous deleterious effects that may stem from increased nitric oxide (NO) scavenging, but has also been associated with reactive oxygen species generation and p
Autor:
Ehsan Shokrollahi, Luc J. W. van der Laan, Wenshi Wang, Lei Xu, Qiuwei Pan, Krzysztof Felczak, Maikel P. Peppelenbosch, Krzysztof W. Pankiewicz, Nicolaas J. H. Raat, Yijin Wang, Dave Sprengers, Herold J. Metselaar, Xinying Zhou
Publikováno v:
Antimicrobial Agents & Chemotherapy, 60(5), 2834-2848. American Society for Microbiology
Viruses are solely dependent on host cells to propagate; therefore, understanding virus-host interaction is important for antiviral drug development. Since de novo nucleotide biosynthesis is essentially required for both host cell metabolism and vira
Publikováno v:
Critical Care, 19. BioMed Central Ltd.
Critical Care
Critical Care
Introduction Although mitochondrial dysfunction is proposed to be involved in the pathophysiology of sepsis, conflicting results are reported. Variation in methods used to assess mitochondrial function might contribute to this controversy. A non-inva