Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Nicola Zambrano"'
Autor:
Guendalina Froechlich, Arianna Finizio, Alessandra Napolano, Sara Amiranda, Arianna De Chiara, Pasqualina Pagano, Massimo Mallardo, Guido Leoni, Nicola Zambrano, Emanuele Sasso
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Different innate immune pathways converge to Stimulator of interferon genes (STING) and trigger type I interferon responses after recognition of abnormal nucleic acids in the cells. This non-redundant function renders STING a major player in
Externí odkaz:
https://doaj.org/article/92093d7dd82e4ff1bfccb46468f53564
Autor:
Mariangela Succoio, Sara Amiranda, Emanuele Sasso, Carmen Marciano, Arianna Finizio, Giuseppina De Simone, Corrado Garbi, Nicola Zambrano
Publikováno v:
Heliyon, Vol 9, Iss 8, Pp e18885- (2023)
The human carbonic anhydrase IX (CA IX) is a hypoxia-induced transmembrane protein belonging to the α-CA enzyme family. It has a crucial role in pH regulation in hypoxic cells and acts by buffering intracellular acidosis induced by hypoxia. Indeed,
Externí odkaz:
https://doaj.org/article/a17f2137ad6844cfbf172125c79239b4
Autor:
Margherita Passariello, Chiara Gentile, Veronica Ferrucci, Emanuele Sasso, Cinzia Vetrei, Giovanna Fusco, Maurizio Viscardi, Sergio Brandi, Pellegrino Cerino, Nicola Zambrano, Massimo Zollo, Claudia De Lorenzo
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Among the therapies against the pandemic SARS-CoV-2 virus, monoclonal Antibodies (mAbs) targeting the Spike glycoprotein represent good candidates to interfere in the Spike/ACE2 interaction, preventing virus cell entry. Since anti-spike mAbs
Externí odkaz:
https://doaj.org/article/522ae82dbfd144feacef1182f8f3bee9
Autor:
Maria De Lucia, Gabriella Cotugno, Veronica Bignone, Irene Garzia, Linda Nocchi, Francesca Langone, Biljana Petrovic, Emanuele Sasso, Simona Pepe, Guendalina Froechlich, Chiara Gentile, Nicola Zambrano, Gabriella Campadelli-Fiume, Alfredo Nicosia, Elisa Scarselli, Anna Morena D’Alise
Publikováno v:
Molecular Therapy: Oncolytics, Vol 19, Iss , Pp 253-264 (2020)
Oncolytic viruses (OVs) are novel anti-tumor agents with the ability to selectively infect and kill tumor cells while sparing normal tissue. Beyond tumor cytolysis, OVs are capable of priming an anti-tumor immune response via lysis and cross-presenta
Externí odkaz:
https://doaj.org/article/b42887904459445c8ca4a40719963797
Autor:
Margherita Passariello, Veronica Ferrucci, Emanuele Sasso, Lorenzo Manna, Rosa Rapuano Lembo, Stefano Pascarella, Giovanna Fusco, Nicola Zambrano, Massimo Zollo, Claudia De Lorenzo
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5556 (2022)
The dramatic experience with SARS-CoV-2 has alerted the scientific community to be ready to face new epidemics/pandemics caused by new variants. Among the therapies against the pandemic SARS-CoV-2 virus, monoclonal Antibodies (mAbs) targeting the Spi
Externí odkaz:
https://doaj.org/article/80e7e43aac304e90a10b58a6b7e3cb11
Autor:
Martin Benej, Eliska Svastova, Radivojka Banova, Juraj Kopacek, Adriana Gibadulinova, Martin Kery, Simona Arena, Andrea Scaloni, Monica Vitale, Nicola Zambrano, Ioanna Papandreou, Nicholas C. Denko, Silvia Pastorekova
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Tumor hypoxia represents a severe microenvironmental stress that is frequently associated with acidosis. Cancer cells respond to these stresses with changes in gene expression that promote survival at least in part through pH regulation and metabolic
Externí odkaz:
https://doaj.org/article/9b8010c39ef64e049616ebd117f253ef
Autor:
Chiara Gentile, Arianna Finizio, Guendalina Froechlich, Anna Morena D’Alise, Gabriella Cotugno, Sara Amiranda, Alfredo Nicosia, Elisa Scarselli, Nicola Zambrano, Emanuele Sasso
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13521 (2021)
Background: Oncolytic viruses are immunotherapeutic agents that can be engineered to encode payloads of interest within the tumor microenvironment to enhance therapeutic efficacy. Their therapeutic potential could be limited by many avenues for immun
Externí odkaz:
https://doaj.org/article/c00e014feb9a45c289fc3c5b76b7337f
Autor:
Anna Maria Salzano, Giovanni Renzone, Anatoly P. Sobolev, Virginia Carbone, Milena Petriccione, Donatella Capitani, Monica Vitale, Gianfranco Novi, Nicola Zambrano, Maria Silvia Pasquariello, Luisa Mannina, Andrea Scaloni
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
Actinidia deliciosa cv. Hayward fruit is renowned for its micro- and macronutrients, which vary in their levels during berry physiological development and postharvest processing. In this context, we have recently described metabolic pathways/molecula
Externí odkaz:
https://doaj.org/article/71ab1db524ba4d098f4715839e28cdc9
Autor:
Guendalina Froechlich, Chiara Gentile, Luigia Infante, Carmen Caiazza, Pasqualina Pagano, Sarah Scatigna, Gabriella Cotugno, Anna Morena D’Alise, Armin Lahm, Elisa Scarselli, Alfredo Nicosia, Massimo Mallardo, Emanuele Sasso, Nicola Zambrano
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 2, p 477 (2021)
Background: HER2-based retargeted viruses are in advanced phases of preclinical development of breast cancer models. Mesothelin (MSLN) is a cell-surface tumor antigen expressed in different subtypes of breast and non-breast cancer. Its recent identif
Externí odkaz:
https://doaj.org/article/9f921a9fca6b41f78ff688e821cd765f
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-1 (2019)
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
Externí odkaz:
https://doaj.org/article/a343345e1795466da33f0b55d7f6708b