Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicola Winstone"'
Autor:
Katie J. Ewer, Tom Ford, Jill Gilmour, Nicola Winstone, Len Dally, Claire Wenden, Josephine H. Cox, Alison Mbekeani, Merribeth Morin, Adrian V. S. Hill
Publikováno v:
Vaccine
Ex vivo functional immunoassays such as ELISpot and intracellular cytokine staining (ICS) by flow cytometry are crucial tools in vaccine development both in the identification of novel immunogenic targets and in the immunological assessment of sample
Autor:
Joanna Roberts, Nicola Winstone, Helen McShane, Julian Sutton, Andrew J. McMichael, Yun-Hsiang Chen, Sandip Patel, Inese Cebere, Mary Brooks, Sarah Rowland-Jones, Tomáš Hanke, Matilu Mwau, Edmund G.-T. Wee, Job J. Bwayo, Lucy Dorrell, C. Schmidt, Priscilla Chikoti, Christopher P. Conlon, Tara S Beattie
The immunogenicities of candidate DNA- and modified vaccinia virus Ankara (MVA)-vectored human immunodeficiency virus (HIV) vaccines were evaluated on their own and in a prime–boost regimen in phase I clinical trials in healthy uninfected individua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32743213fc71c5f8033454edfc0b63bf
https://doi.org/10.1099/vir.0.19701-0
https://doi.org/10.1099/vir.0.19701-0
Autor:
Tomáš Hanke, Pat Fast, Susana Pinheiro, Mark Boaz, Jill Gilmour, Inese Cebere, Nilu Goonetilleke, Joanna Roberts, Jan De Bont, Vanessa Loach, Stephen Moore, C. Schmidt, Peter Hayes, Geraldine M. Gillespie, Carl Verlinde, Denise Brown, Andrew J. McMichael, Nicola Winstone, Len Dally, Kelley Loughran, Carole Smith, Ana Guimarães-Walker, Danii Vooijs, Lucy Dorrell, Abdul Mahmoud
A double-blind randomized phase I trial was conducted in human immunodeficiency virus type 1 (HIV-1)-negative subjects receiving vaccines vectored by plasmid DNA and modified vaccinia virus Ankara (MVA) expressing HIV-1 p24/p17 gag linked to a string
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fda65e76e706519bfaac5c611924e1
https://ora.ox.ac.uk/objects/uuid:f2bd0c17-64b0-4cc7-af02-205f0689635b
https://ora.ox.ac.uk/objects/uuid:f2bd0c17-64b0-4cc7-af02-205f0689635b
Autor:
Ana Guimarães-Walker, Nilu Goonetilleke, Vanessa Loach, Andrew J. McMichael, Tomáš Hanke, Joanna Roberts, Nicola Winstone, Denise Brown
Publikováno v:
European Journal of Immunology. 39:975-985
Induction of a long-term immunological memory, which can expand and defend the host upon pathogen encounter, is the "holy grail" of vaccinology. Here, using a sensitive cultured IFN-gamma ELISPOT assay, we show that 50% (15 out of 30) of healthy, HIV
Autor:
Aaron J. Wilson, Feng Lin, Karl Mullen, Ian Ouellette, Christopher L. Parks, John W. Coleman, George N. Pavlakis, Barbara K. Felber, M Kemelman, Maria J. Chiuchiolo, Chih Da Wu, Dawn McBride, Holly Cassamasa, Arielle A. Ginsberg, Alan M. Schultz, Adrian B. McDermott, Sandeep Narpala, Gavin Morrow, Michael G. Hudgens, Mary Lopez, Cesar Boggiano, C. Richter King, Niranjan Y. Sardesai, Hansi J. Dean, Nicola Winstone, Timothy J. Zamb
Publikováno v:
Journal of virology. 85(18)
DNA priming has previously been shown to elicit augmented immune responses when administered by electroporation (EP) or codelivered with a plasmid encoding interleukin-12 (pIL-12). We hypothesized that the efficacy of a DNA prime and recombinant aden
Autor:
Patricia E. Fast, S. Moore, Nilu Goonetilleke, Nicola Winstone, Carol Smith, Peter Hayes, Burc Barin, A. Guimarães-Walker, Lucy Dorrell, Sheena McCormack, Andrew J. McMichael, Len Dally, Jonathan Weber, Inese Cebere, Abdel Babiker, Tomáš Hanke, Frances Gotch, Jill Gilmour, C. Schmidt, R. Kay, Nicola Mackie, K. Legg
Publikováno v:
Vaccine.
orrigendum to “Lessons from IAVI-006, a Phase I clinical trial to evaluate the afety and immunogenicity of the pTHr.HIVA DNA and MVA.HIVA vaccines in a rime-boost strategy to induce HIV-1 specific T-cell responses in healthy olunteers” [Vaccine 2
Autor:
Paul Bowness, Tao Dong, Persephone Borrow, Nicola Winstone, Andrew J. McMichael, Hongbing Yang, K di Gleria, Tomáš Hanke, B Ondondo, Lucy Dorrell, Ranasinghe, N Goonetilleke, Emma L. Turnbull, Christopher P. Conlon
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 179(1)
During chronic HIV-1 infection, continuing viral replication is associated with impaired proliferative capacity of virus-specific CD8+ T cells and with the expansion and persistence of oligoclonal T cell populations. TCR usage may significantly influ
Publikováno v:
Retrovirology
Retrovirology, Vol 6, Iss Suppl 3, p P280 (2009)
Retrovirology, Vol 6, Iss Suppl 3, p P280 (2009)