Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nicola Sinden"'
Autor:
Peter Griffiths, Christina Saville, Jane E Ball, Rosemary Chable, Andrew Dimech, Jeremy Jones, Yvonne Jeffrey, Natalie Pattison, Alejandra Recio Saucedo, Nicola Sinden, Thomas Monks
Publikováno v:
Health Services and Delivery Research, Vol 8, Iss 16 (2020)
Background: The Safer Nursing Care Tool is a system designed to guide decisions about nurse staffing requirements on hospital wards, in particular the number of nurses to employ (establishment). The Safer Nursing Care Tool is widely used in English h
Externí odkaz:
https://doaj.org/article/5f43ebb556af43d7afedc914caa70232
Autor:
Peter Griffiths, Jane Ball, Karen Bloor, Dankmar Böhning, Jim Briggs, Chiara Dall’Ora, Anya De Iongh, Jeremy Jones, Caroline Kovacs, Antonello Maruotti, Paul Meredith, David Prytherch, Alejandra Recio Saucedo, Oliver Redfern, Paul Schmidt, Nicola Sinden, Gary Smith
Publikováno v:
Health Services and Delivery Research, Vol 6, Iss 38 (2018)
Background: Low nurse staffing levels are associated with adverse patient outcomes from hospital care, but the causal relationship is unclear. Limited capacity to observe patients has been hypothesised as a causal mechanism. Objectives: This study de
Externí odkaz:
https://doaj.org/article/c35bfc87c44b4cac9e7dc4a94de51587
Autor:
Andrew Dimech, Rosemary Chable, Christina Saville, Jeremy Jones, Nicola Sinden, Alejandra Recio Saucedo, Natalie Pattison, Thomas Monks, Yvonne Jeffrey, Jane Ball, Peter Griffiths
Publikováno v:
Health Services and Delivery Research, Vol 8, Iss 16 (2020)
BackgroundThe Safer Nursing Care Tool is a system designed to guide decisions about nurse staffing requirements on hospital wards, in particular the number of nurses to employ (establishment). The Safer Nursing Care Tool is widely used in English hos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::297eab1137fcabeb81c0fc876aa56589
https://eprints.soton.ac.uk/435259/
https://eprints.soton.ac.uk/435259/
Autor:
Nicola Sinden, Michael Baker, Jan-Ulrich Kreft, David J. Smith, Robert A. Stockley, Timothy R. Dafforn
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 308:L179-L190
The excessive activities of the serine proteinases neutrophil elastase and proteinase 3 are associated with tissue damage in chronic obstructive pulmonary disease. Reduced concentrations and/or inhibitory efficiency of the main circulating serine pro
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 306:L80-L87
Progranulin (PGRN) is an anti-inflammatory protein, yet its digestion by neutrophil-derived proteinases generates products that can stimulate epithelial cell lines to secrete the neutrophil chemoattractant interleukin (IL)-8. Because dysregulated neu
Autor:
Nicola Sinden, Robert A. Stockley
Publikováno v:
Thorax. 65:930-936
Chronic obstructive pulmonary disease (COPD) is characterised by an inflammatory response by the lungs to inhaled substances such as cigarette smoking and air pollutants. In addition to the pulmonary features of COPD, several systemic effects have be
Autor:
Nicola Sinden, Robert A. Stockley
Publikováno v:
The European respiratory journal. 41(5)
Chronic obstructive pulmonary disease (COPD) is associated with tissue damage believed to result from an imbalance between serine proteinases and their inhibitors. Although the role of neutrophil elastase (NE) has been studied, it is likely that othe
Publikováno v:
Family practice. 20(4)
BACKGROUND The number of females entering and graduating from medical school is currently increasing and, as a result, the problems they face if they wish to work as doctors and have a family are becoming more apparent. METHODS A questionnaire study
Publikováno v:
Thorax. 67:A41.3-A42
Introduction Serine proteinases such as proteinase 3 (PR3) and neutrophil elastase (NE) on the surface of activated neutrophils retain their activity, which may be central to the tissue damage in emphysema. However, little is known about this express
Publikováno v:
Thorax. 67:A174.1-A174
Background Progranulin (PGRN) is an anti-inflammatory protein, which is converted into pro-inflammatory granulin peptides (GRNs) by neutrophil elastase (NE) and proteinase-3 (PR3) (1). Neutrophilic inflammation is implicated in the pathophysiology of