Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Nicola Silva"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 5 (2022)
AbstractGeneration of functional gametes is accomplished through a multilayered and finely orchestrated succession of events during meiotic progression. In the Caenorhabditis elegansS285htp-3S285A
Externí odkaz:
https://doaj.org/article/8a945bad272d443c82b71327ffafd703
Autor:
Eva Janisiw, Marilina Raices, Fabiola Balmir, Luis F. Paulin, Antoine Baudrimont, Arndt von Haeseler, Judith L. Yanowitz, Verena Jantsch, Nicola Silva
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Poly(ADP-ribose) glycohydrolase (PARG) is involved in different cellular processes including DNA repair. Here the authors reveal a role for PARG in regulating meiotic DNA double strand break induction and repair in Caenorhabditis elegans.
Externí odkaz:
https://doaj.org/article/6fbdd58c4ad94b98ba5e66e4807523fd
Autor:
Nicola Silva, Maikel Castellano-Pozo, Kenichiro Matsuzaki, Consuelo Barroso, Monica Roman-Trufero, Hannah Craig, Darren R Brooks, R Elwyn Isaac, Simon J Boulton, Enrique Martinez-Perez
Publikováno v:
PLoS Genetics, Vol 18, Iss 1, p e1010025 (2022)
Genotoxic stress during DNA replication constitutes a serious threat to genome integrity and causes human diseases. Defects at different steps of DNA metabolism are known to induce replication stress, but the contribution of other aspects of cellular
Externí odkaz:
https://doaj.org/article/a96ac9391b0141f5855e9de298dde95f
Autor:
Maria Velkova, Nicola Silva, Maria Rosaria Dello Stritto, Alexander Schleiffer, Pierre Barraud, Markus Hartl, Verena Jantsch
Publikováno v:
PLoS Genetics, Vol 17, Iss 7, p e1009663 (2021)
Homologous recombination is a high-fidelity repair pathway for DNA double-strand breaks employed during both mitotic and meiotic cell divisions. Such repair can lead to genetic exchange, originating from crossover (CO) generation. In mitosis, COs are
Externí odkaz:
https://doaj.org/article/56b6564b61ed487d9aea33eb522767d6
Publikováno v:
PLoS Genetics, Vol 14, Iss 11, p e1007653 (2018)
During meiosis, the maternal and paternal homologous chromosomes must align along their entire length and recombine to achieve faithful segregation in the gametes. Meiotic recombination is accomplished through the formation of DNA double-strand break
Externí odkaz:
https://doaj.org/article/4e396636644a40f88290fa3fbdf53450
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007776 (2018)
Correct segregation of meiotic chromosomes depends on DNA crossovers (COs) between homologs that culminate into visible physical linkages called chiasmata. COs emerge from a larger population of joint molecules (JM), the remainder of which are repair
Externí odkaz:
https://doaj.org/article/04cd91be487743699543d8d9f31b0e5d
Autor:
Ye Hong, Maria Velkova, Nicola Silva, Marlène Jagut, Viktor Scheidt, Karim Labib, Verena Jantsch, Anton Gartner
Publikováno v:
PLoS Genetics, Vol 14, Iss 6, p e1007453 (2018)
Homologous recombination is essential for crossover (CO) formation and accurate chromosome segregation during meiosis. It is of considerable importance to work out how recombination intermediates are processed, leading to CO and non-crossover (NCO) o
Externí odkaz:
https://doaj.org/article/64caa845417046a49b92c42a3a4e1320
Autor:
Oliver Crawley, Consuelo Barroso, Sarah Testori, Nuria Ferrandiz, Nicola Silva, Maikel Castellano-Pozo, Angel Luis Jaso-Tamame, Enrique Martinez-Perez
Publikováno v:
eLife, Vol 5 (2016)
Wapl induces cohesin dissociation from DNA throughout the mitotic cell cycle, modulating sister chromatid cohesion and higher-order chromatin structure. Cohesin complexes containing meiosis-specific kleisin subunits govern most aspects of meiotic chr
Externí odkaz:
https://doaj.org/article/4b4e7c5ddc494e91840a5f486dd22405
Publikováno v:
Nucleic acids research.
Meiotic chromosome segregation relies on programmed DNA double-strand break induction. These are in turn repaired by homologous recombination, generating physical attachments between the parental chromosomes called crossovers. A subset of breaks yiel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e0cdab4222b5f0907eb52bfd8121ea9
https://pubmed.ncbi.nlm.nih.gov/36478097
https://pubmed.ncbi.nlm.nih.gov/36478097
During meiosis, accurate chromosome segregation relies on the formation of programmed DNA double-strand breaks (DSBs). These are in turn repaired by homologous recombination (HR), generating physical attachments between the parental chromosomes calle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2702c52620222c5ac78d6f6da849495
https://doi.org/10.1101/2022.06.14.496162
https://doi.org/10.1101/2022.06.14.496162
