Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicola P. Caradonna"'
Autor:
Nicola P. Caradonna, Serena Pasquini, Antonella Brizzi, Roger G. Pertwee, Federico Corelli, Maria Cristina De Rosa, Daniele Bolognini, Maria Grazia Cascio, Alessia Ligresti, Claudia Mugnaini, Vincenzo Di Marzo
Publikováno v:
European Journal of Medicinal Chemistry. 58:30-43
Within our studies on structure-activity relationships of 4-quinolone-3-carboxamides as cannabinoid ligands, a new series of compounds characterized by a fluoro or phenylthio group at 7-position and different substituents at N1 and carboxamide nitrog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180ee9bcc93cead764d274d0f6325dc5
https://doi.org/10.1016/j.ejmech.2012.09.035
https://doi.org/10.1016/j.ejmech.2012.09.035
Autor:
Silvia Valensin, Enrica Diodato, Elena Pilli, Carla Scali, Luisa Massai, Roberta Magrini, Riccardo Roggeri, Antonella De Rosa, Fabio A. Recchia, Nicola P. Caradonna, Sara Chellini, Giuseppe Pollio, Patrizia Tunici, Valentina Porcari, Gianluca Sardone, Pasquale Fiengo, Letizia Magnoni, Silvia Coniglio, Vincenzo Lionetti, Daniela Diamanti, Martina Monti, Marco Rossi
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 86
Preclinical imaging modalities represent an essential tool to develop a modern and translational biomedical research. To date, Optical Imaging (OI) and Magnetic Resonance Imaging (MRI) are used principally in separate studies for molecular imaging st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eefa3a8496dafc1a16a3288254431bcc
https://pubmed.ncbi.nlm.nih.gov/26987608
https://pubmed.ncbi.nlm.nih.gov/26987608
Autor:
Matteo Andreini, Annette Bakker, Martina Nibbio, Federica Mennillo, Alessandra De Robertis, Elisa Turlizzi, Tiziana Benicchi, Ugo Zanelli, Matteo Magnani, Maurizio Varrone, Marco Rossi, Federico Cappelli, Nicola P. Caradonna, Carmela Pratelli, Patrizia Tunici, Arianna Nencini, Silvia Valensin, Joanna Quinn, Massimiliano Salerno
Publikováno v:
European journal of medicinal chemistry. 95
Wnt signaling pathway plays a critical role in numerous cellular processes, including tumor initiation, proliferation, invasion/infiltration, metastasis formation and resistance to chemotherapy. In a drug discovery project aimed at the identification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b81949a8a942e1517a5eeb788d199e14
https://pubmed.ncbi.nlm.nih.gov/25847770
https://pubmed.ncbi.nlm.nih.gov/25847770
Autor:
Nicola P. Caradonna, Giulia Lazzeroni, David C. Rubinsztein, Fiona M. Menzies, Alessia Tarditi, Venkata P. Satagopam, Valentina Porcari, Angeleen Fleming, Reinhard Schneider, Freddy Heitz, Chiara Caramelli, Birte Sönnichsen, Maria Jimenez-Sanchez, Carla Scali, Sara Imarisio, Michael Hannus, Giuseppe Pollio, Wun Lam, Daniela Diamanti, Catherine K. Xu, Eduardo Gonzalez-Couto, Arianna Nencini, Gian Luca Sardone, Andrea Caricasole, Cahir J. O'Kane, Matteo Andreini, Luisa Massai, Guido Marconi, Teresa Ed Dami
Publikováno v:
Nature chemical biology
Nature chemical biology, 11(5), 347–354. (2015).
Nature chemical biology, 11(5), 347–354. (2015).
Huntington’s disease (HD) is a currently incurable neurodegenerative condition caused by an abnormally expanded polyglutamine tract in huntingtin (HTT). We identified novel modifiers of mutant HTT toxicity by performing a large-scale “druggable g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16393671b3fab8f3aca4e9d91caa8e6
https://pubmed.ncbi.nlm.nih.gov/25848931
https://pubmed.ncbi.nlm.nih.gov/25848931
Autor:
Elisa Mori, Nicola P. Caradonna, Maurizio Varrone, Massimiliano Salerno, Patrizia Tunici, Alessandra De Robertis, Marco Rossi, Silvia Valensin, Federica Mennillo
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97847 (2014)
PLoS ONE
PLoS ONE
Sarcomas are mesenchymal tumors showing high molecular heterogeneity, reflected at the histological level by the existence of more than fifty different subtypes. Genetic and epigenetic evidences link aberrant activation of the Wnt signaling to growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889cc4a0e73c3a1be52c3345209e02f0
http://europepmc.org/articles/PMC4026528?pdf=render
http://europepmc.org/articles/PMC4026528?pdf=render
Autor:
Oskar Hoffmann, Maurizio Botta, Francesco Bondavalli, Nicola P. Caradonna, Adriano Spreafico, Mauro Bologna, and Adriano Angelucci, Giada A. Locatelli, Angelo Ranise, Olga Bruno, Chiara Brullo, Maurizio Orlandini, Annalisa Santucci, Andrea Spallarossa, Silvia Schenone, Giulia Bernardini, Tommaso Serchi, Fabrizio Manetti, Giovanni Maga
Publikováno v:
Journal of medicinal chemistry. 50(23)
New pyrazolo[3,4-d]pyrimidines were synthesized and found to inhibit Src phosphorylation in a cell-free assay. Some of them significantly reduced the growth of human osteogenic sarcoma (SaOS-2) cells. The best compound, in terms of inhibitory propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58a1e002196cf30425ab0adc289071de
https://pubmed.ncbi.nlm.nih.gov/17929792
https://pubmed.ncbi.nlm.nih.gov/17929792
Autor:
Fabrizio Manetti, Annalisa Santucci, Giada A. Locatelli, Giovanni Maga, Adriano Spreafico, Tommaso Serchi, Maurizio Orlandini, Giulia Bernardini, Nicola P. Caradonna, Andrea Spallarossa, Chiara Brullo, Silvia Schenone, Olga Bruno, Angelo Ranise, Francesco Bondavalli, Oskar Hoffmann, Mauro Bologna, Adriano Angelucci, Maurizio Botta
Publikováno v:
Journal of Medicinal Chemistry; Nov2007, Vol. 50 Issue 23, p5579-5588, 10p