Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Nicola Mongelli"'
Publikováno v:
Journal of Archaeological Science: Reports. 45:103553
Autor:
Paolo Romita, Francesca Ambrogio, Angela Stufano, Piero Lovreglio, Nicola Mongelli, Pasquale Acquafredda, Gerardo Cazzato, Caterina Foti
Publikováno v:
Contact Dermatitis. 84:359-360
Autor:
Angela Stufano, Caterina Foti, Paolo Romita, Piero Lovreglio, Francesca Ambrogio, Nicola Mongelli, Pasquale Acquafredda
Publikováno v:
Contact Dermatitis. 83:66-67
Autor:
Silvia, Pezzola, Giovanni, Antonini, Cristina, Geroni, Italo, Beria, Maristella, Colombo, Massimo, Broggini, Sergio, Marchini, Nicola, Mongelli, Loris, Leboffe, Robert, MacArthur, Alessia Francesca, Mozzi, Giorgio, Federici, Anna Maria, Caccuri
Publikováno v:
Biochemistry. 49:226-235
Brostallicin is a novel and unique glutathione transferase-activated pro-drug with promising anticancer activity, currently in phase I and II clinical evaluation. In this work, we show that, in comparison with the parental cell line showing low GST l
Autor:
Roberto Gambari, Giampiero Spalluto, Paolo Cozzi, Nicola Mongelli, Nicoletta Bianchi, Pier Giovanni Baraldi, Romeo Romagnoli
Publikováno v:
Arzneimittelforschung. 50:309-315
The linkage of an heterocycle, like N-methylimidazole, to minor DNA groove binders containing two or three pyrroles lead to a new class of oligopeptides with reduced antitumor activity both in vitro and in vivo if compared to tallimustine (CAS 115308
Autor:
Daniela Borghi, Francesca Quartieri, Gianluca Papeo, Nicola Mongelli, Helena Posteri, Federico Tutino
Publikováno v:
Tetrahedron. 65:2372-2376
(Z)-Axinohydantoin and (Z)-debromoaxinohydantoin, two pyrrole–imidazole alkaloids isolated from different marine sponges, possess moderate activities in inhibiting the progress of the cell cycle at different phases. A stereoselective synthesis of b
Autor:
Paolo Cozzi, Paolo Lusso, Mauro S. Malnati, Priscilla Biswas, Daniela Jabes, Francesca Sironi, Adolfo García-Sastre, Silvia Ghezzi, Christina Guzzo, Nicola Mongelli, Carles Martínez-Romero
Publikováno v:
Journal of Translational Medicine
Background Combined antiretroviral therapy has drastically reduced mortality and morbidity of HIV-infected individuals. Nevertheless long-term toxicity and appearance of viral resistance hampers the prolonged effectiveness of combination therapy, req
Autor:
Detlef Moskau, Claudio Dalvit, Rainer Kümmerle, Gianluca Papeo, Patrizia Giordano, Marina Veronesi, Nicola Mongelli
Publikováno v:
Journal of the American Chemical Society. 127:13380-13385
NMR-based binding and functional screening performed with FAXS (fluorine chemical shift anisotropy and exchange for screening) and 3-FABS (three fluorine atoms for biochemical screening) represents a potential alternative approach to high-throughput
Autor:
Marina Veronesi, Gianluca Papeo, Beatrice Saccardo, Claudio Dalvit, Nicola Mongelli, Patrizia Giordano, Alessia Costa, Soo Y. Ko
Publikováno v:
Drug Development Research. 64:105-113
NMR-based functional screening performed with 3-FABS represents a reliable method for identifying inhibitors and measuring with high accuracy their inhibitory activity. Although the method scores high in quality, in its current status it cannot compe
Publikováno v:
Drug Discovery Today. 9:595-602
An NMR method called 3-FABS has extended the capabilities of NMR, enabling rapid, efficient and reliable high-throughput functional screening for the identification of inhibitors and for measuring their 50% mean inhibition concentration (IC50) with a