Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicola M Blythe"'
Autor:
Nick A Maskell, Clare Clement, Jodi Taylor, Daisy Gaunt, Chris Metcalfe, Edward Carlton, Fiona Lecky, Douglas West, Rebecca Kandiyali, Madeleine Clout, Julian Thompson, Sophie Rees, Jonathan Banks, J Athene Lane, Antoinette Edwards, Steven Walker, Jonathan R Benger, Nicola M Blythe, Katherine Coates, Ammar Annaw, Marie Platt
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Traumatic pneumothoraces are present in one of five victims of severe trauma. Current guidelines advise chest drain insertion for most traumatic pneumothoraces, although very small pneumothoraces can be managed with observation at the tr
Externí odkaz:
https://doaj.org/article/36c36c2e7b6842b4a1f78efed69852d8
Autor:
Fiona Bartoli, Elizabeth L. Evans, Nicola M. Blythe, Leander Stewart, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Katie E. Musialowski, Laeticia Lichtenstein, Gregory Parsonage, T. Simon Futers, Neil A. Turner, David J. Beech
Publikováno v:
Cells, Vol 11, Iss 7, p 1199 (2022)
PIEZO1 is a subunit of mechanically-activated, nonselective cation channels. Gain-of-function PIEZO1 mutations are associated with dehydrated hereditary stomatocytosis (DHS), a type of anaemia, due to abnormal red blood cell function. Here, we hypoth
Externí odkaz:
https://doaj.org/article/932ca224765f4a809c1c748ab19616bf
Autor:
Neil A. Turner, Nicola M. Blythe
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 6, Iss 3, p 27 (2019)
The cardiac fibroblast is a remarkably versatile cell type that coordinates inflammatory, fibrotic and hypertrophic responses in the heart through a complex array of intracellular and intercellular signaling mechanisms. One important signaling node t
Externí odkaz:
https://doaj.org/article/be14b8012752429aab50fe163ea8d617
Autor:
Karen E. Porter, Frans A. van Nieuwenhoven, Vasili Stylianidis, Richard Foster, Nicola M Blythe, Neil A. Turner, Katsuhiko Muraki, Jing Li, Hamish T. J. Gilbert, Kevin Cuthbertson, Mark J. Drinkhill, David J. Beech, Elizabeth L. Evans, Joe Swift, Melanie J. Ludlow
Publikováno v:
Journal of Biological Chemistry, 294(46), 17395-17408. American Society for Biochemistry and Molecular Biology, Inc.
Blythe, N M, Muraki, K, Ludlow, M J, Stylianidis, V, Gilbert, H T J, Evans, E L, Cuthbertson, K, Foster, R, Swift, J, Li, J, Drinkhill, M J, van Nieuwenhoven, F A, Porter, K E, Beech, D J & Turner, N A 2019, ' Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion ', The Journal of biological chemistry . https://doi.org/10.1074/jbc.RA119.009167
The Journal of Biological Chemistry
Blythe, N M, Muraki, K, Ludlow, M J, Stylianidis, V, Gilbert, H T J, Evans, E L, Cuthbertson, K, Foster, R, Swift, J, Li, J, Drinkhill, M J, van Nieuwenhoven, F A, Porter, K E, Beech, D J & Turner, N A 2019, ' Mechanically activated Piezo1 channels of cardiac fibroblasts stimulate p38 mitogen-activated protein kinase activity and interleukin-6 secretion ', The Journal of biological chemistry . https://doi.org/10.1074/jbc.RA119.009167
The Journal of Biological Chemistry
Piezo1 is a mechanosensitive cation channel with widespread physiological importance; however, its role in the heart is poorly understood. Cardiac fibroblasts help preserve myocardial integrity and play a key role in regulating its repair and remodel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9105908f59f377a695a247e5ae82f4b9
https://doi.org/10.1074/jbc.ra119.009167
https://doi.org/10.1074/jbc.ra119.009167
Autor:
Nicola M Blythe, Neil A. Turner
Publikováno v:
Journal of Cardiovascular Development and Disease, Vol 6, Iss 3, p 27 (2019)
Journal of cardiovascular development and disease
Journal of Cardiovascular Development and Disease
Journal of cardiovascular development and disease
Journal of Cardiovascular Development and Disease
The cardiac fibroblast is a remarkably versatile cell type that coordinates inflammatory, fibrotic and hypertrophic responses in the heart through a complex array of intracellular and intercellular signaling mechanisms. One important signaling node t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9533e86a7d421f48d261742ae34b1cab
https://www.mdpi.com/2308-3425/6/3/27
https://www.mdpi.com/2308-3425/6/3/27
Autor:
Melanie J. Ludlow, Karen E. Porter, Stylianidis, Elizabeth L. Evans, Frans A. van Nieuwenhoven, David J. Beech, Nicola M Blythe, Gilbert Htj, Neil A. Turner, Kevin Cuthbertson, Jing Li, Joe Swift, Mark J. Drinkhill, Richard Foster
Piezo1 is a mechanosensitive cation channel with widespread physiological importance; however its role in the heart is poorly understood. Cardiac fibroblasts are responsible for preserving the structural integrity of the myocardium and play a key rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf50d66cb1e0c0d4e611551637d7e25f
Autor:
Jacqueline, Naylor, Aisling, Minard, Hannah J, Gaunt, Mohamed S, Amer, Lesley A, Wilson, Marco, Migliore, Sin Y, Cheung, Hussein N, Rubaiy, Nicola M, Blythe, Katie E, Musialowski, Melanie J, Ludlow, William D, Evans, Ben L, Green, Hongjun, Yang, Yun, You, Jing, Li, Colin W G, Fishwick, Katsuhiko, Muraki, David J, Beech, Robin S, Bon
Publikováno v:
British Journal of Pharmacology
Background and Purpose The TRPC5 proteins assemble to create calcium‐permeable, non‐selective, cationic channels. We sought novel modulators of these channels through studies of natural products. Experimental Approach Intracellular calcium measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7eea1e8bc9f669ef9b57b6b348be79e