Zobrazeno 1 - 10
of 13 757
pro vyhledávání: '"Nicola M"'
Autor:
Nicola M. Sergienko, Adam J. Trewin, Helen Kiriazis, Antonia J. A. Raaijmakers, Daniel G. Donner, Victoria C. Garside, Kelly A. Smith, James R. Bell, Kimberley M. Mellor, Lea M. D. Delbridge, Julie R. McMullen, Kate L. Weeks
Publikováno v:
npj Metabolic Health and Disease, Vol 2, Iss 1, Pp 1-13 (2024)
Abstract Protein phosphatase 2A (PP2A) regulatory subunit B55α has been implicated in the transcriptional regulation of cardiac growth and fibrosis by suppressing HDAC5/MEF2 signalling in cardiomyocytes. We created and characterised two mouse models
Externí odkaz:
https://doaj.org/article/962f0a0f34444cd0b5607aa60b031817
Autor:
Sahar Jaddi, M. Wasil Malik, Bin Wang, Nicola M. Pugno, Yun Zeng, Michael Coulombier, Jean-Pierre Raskin, Thomas Pardoen
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Fail-safe design of devices requires robust integrity assessment procedures which are still absent for 2D materials, hence affecting transfer to applications. Here, a combined on-chip tension and cracking method, and associated data reductio
Externí odkaz:
https://doaj.org/article/69e41d9669a042af814cce2b420f62df
Autor:
Thomas Eden, Alessa Z. Schaffrath, Janusz Wesolowski, Tobias Stähler, Natalie Tode, Nathalie Richter, Waldemar Schäfer, Julia Hambach, Irm Hermans-Borgmeyer, Jannis Woens, Camille M. Le Gall, Sabrina Wendler, Christian Linke-Winnebeck, Martina Stobbe, Iwona Budnicki, Amelie Wanney, Yannic Heitz, Lena Schimmelpfennig, Laura Schweitzer, Dennis Zimmer, Erik Stahl, Fabienne Seyfried, Anna J. Gebhardt, Lynn Dieckow, Kristoffer Riecken, Boris Fehse, Peter Bannas, Tim Magnus, Martijn Verdoes, Carl G. Figdor, Klaus F. Hartlepp, Hubertus Schleer, Jonas Füner, Nicola M. Tomas, Friedrich Haag, Björn Rissiek, Anna M. Mann, Stephan Menzel, Friedrich Koch-Nolte
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Due to their exceptional solubility and stability, nanobodies have emerged as powerful building blocks for research tools and therapeutics. However, their generation in llamas is cumbersome and costly. Here, by inserting an engineered llama
Externí odkaz:
https://doaj.org/article/06c0fed6be0b4da1ae092b68397ac332
Autor:
Ionel Sandovici, Denise S. Fernandez-Twinn, Niamh Campbell, Wendy N. Cooper, Yoichi Sekita, Ilona Zvetkova, David Ferland-McCollough, Haydn M. Prosser, Lila M. Oyama, Lucas C. Pantaleão, Danilo Cimadomo, Karina Barbosa de Queiroz, Cecilia S.K. Cheuk, Nicola M. Smith, Richard G. Kay, Robin Antrobus, Katharina Hoelle, Marcella K.L. Ma, Noel H. Smith, Stefan H. Geyer, Lukas F. Reissig, Wolfgang J. Weninger, Kenneth Siddle, Anne E. Willis, Brian Y.H. Lam, Martin Bushell, Susan E. Ozanne, Miguel Constância
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114750- (2024)
Summary: Mir483 is a conserved and highly expressed microRNA in placental mammals, embedded within the Igf2 gene. Its expression is dysregulated in a number of human diseases, including metabolic disorders and certain cancers. Here, we investigate th
Externí odkaz:
https://doaj.org/article/abbc32c9c19d41bf953422abe96dc435
Autor:
Connor N. Brown, Babar Shahzad, Mukhtiar Zaman, Xiaobei Pan, Brian D. Green, Nicola M. Lowe, Imre Lengyel
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
BackgroundBiofortified Zinc Flour to Eliminate Deficiency in Pakistan (BiZiFED) is a nutritional research program that evaluates the impact of consuming zinc biofortified wheat flour on zinc status and associated health outcomes of vulnerable communi
Externí odkaz:
https://doaj.org/article/9b6332dd3467449388ca6bce668173ea
Publikováno v:
Maternal and Child Nutrition, Vol 20, Iss 3, Pp n/a-n/a (2024)
Abstract The aim of this study was to investigate household food security (access) level and the dietary diversity of households in the Nsukka Local Government Area in South‐eastern Nigeria. From 20 local communities of Nsukka, 390 women were rando
Externí odkaz:
https://doaj.org/article/50249671e2674318b3f612b2c87e144d
Autor:
Devon J Boland, Nicola M Ayres
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012123 (2024)
AlphaFold2 is an Artificial Intelligence-based program developed to predict the 3D structure of proteins given only their amino acid sequence at atomic resolution. Due to the accuracy and efficiency at which AlphaFold2 can generate 3D structure predi
Externí odkaz:
https://doaj.org/article/9873c6cf0e444438838122a7fb70959d
Autor:
Sawudatu Zakariah-Akoto, Harmony Omeife, Victoria Moran Hall, Godfred Egbi, Seth Adu-Afurwuah, Nicola M Lowe, Richmond Aryeetey
Publikováno v:
World Nutrition, Vol 15, Iss 2 (2024)
Background and Objective Anaemia among pregnant women is a public health challenge in Ghana. Although there is a national programme of routine iron-folic acid (IFA) supplementation, coverage is suboptimal. The current study explored experiences and p
Externí odkaz:
https://doaj.org/article/89eb4bb70f824139a99ea0170183f0d4
Autor:
Nick A Maskell, Clare Clement, Jodi Taylor, Daisy Gaunt, Chris Metcalfe, Edward Carlton, Fiona Lecky, Douglas West, Rebecca Kandiyali, Madeleine Clout, Julian Thompson, Sophie Rees, Jonathan Banks, J Athene Lane, Antoinette Edwards, Steven Walker, Jonathan R Benger, Nicola M Blythe, Katherine Coates, Ammar Annaw, Marie Platt
Publikováno v:
BMJ Open, Vol 14, Iss 6 (2024)
Introduction Traumatic pneumothoraces are present in one of five victims of severe trauma. Current guidelines advise chest drain insertion for most traumatic pneumothoraces, although very small pneumothoraces can be managed with observation at the tr
Externí odkaz:
https://doaj.org/article/36c36c2e7b6842b4a1f78efed69852d8
Autor:
Courtney A. Miller, Geraud C. Tasse Taboue, Eric B. Fokam, Katy Morgan, Ying Zhen, Ryan J. Harrigan, Vinh Le Underwood, Kristen Ruegg, Paul R. Sesink Clee, Stephan Ntie, Patrick Mickala, Jean Francois Mboumba, Trevon Fuller, Breda M. Zimkus, Thomas B. Smith, Nicola M. Anthony
Publikováno v:
Frontiers in Conservation Science, Vol 5 (2024)
Central African rainforests are predicted to be disproportionately affected by future climate change. How species will cope with these changes is unclear, but rapid environmental changes will likely impose strong selection pressures. Here we examined
Externí odkaz:
https://doaj.org/article/83e56690dec54e9e947794f9717eea3d