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pro vyhledávání: '"Nicola Luise"'
Publikováno v:
European Journal of Organic Chemistry. 2019:1341-1349
Autor:
Nicola Luise, Paul G. Wyatt
Publikováno v:
Chemistry - A European Journal. 24:10443-10451
Synthesising polar semi-saturated bicyclic heterocycles can lead to better starting points for fragment-based drug discovery (FBDD) programs. We report the application of diverse chemistry to construct bicyclic systems from a common intermediate, whe
Autor:
Paul G. Wyatt, Nicola Luise
Publikováno v:
Bioorganicmedicinal chemistry letters. 29(2)
An innovative and efficient reagent- and scaffold-based diversity oriented synthesis (DOS) of a fragment set was developed for fragment-based drug discovery (FBDD) programs. Twelve diverse, functionalized and bicyclic scaffolds were rapidly accessed
Publikováno v:
All Days.
Thick allochthonous salt masses that pierced the seafloor in the formation of salt-cored folds flowed laterally downdip to form canopies above turbidite exploration targets. This acoustic configuration has created ray path and contrast difficulties f
Publikováno v:
All Days.
Pore Volume Compressibility (PVC) is one of the most important parameters for proceeding with project sanctioning. An accurate estimation of pore volume compressibility of reservoir rocks is essential for compaction evaluation, reservoir drive determ