Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nicola L. Bird"'
Autor:
Lukasz Kedzierski, Michelle D Tate, Alan C Hsu, Tatiana B Kolesnik, Edmond M Linossi, Laura Dagley, Zhaoguang Dong, Sarah Freeman, Giuseppe Infusini, Malcolm R Starkey, Nicola L Bird, Simon M Chatfield, Jeffrey J Babon, Nicholas Huntington, Gabrielle Belz, Andrew Webb, Peter AB Wark, Nicos A Nicola, Jianqing Xu, Katherine Kedzierska, Philip M Hansbro, Sandra E Nicholson
Publikováno v:
eLife, Vol 6 (2017)
Influenza virus infections have a significant impact on global human health. Individuals with suppressed immunity, or suffering from chronic inflammatory conditions such as COPD, are particularly susceptible to influenza. Here we show that suppressor
Externí odkaz:
https://doaj.org/article/1e6a3080baa04d2a86774d6d71b6e598
Autor:
Katherine Kedzierska, Dale I. Godfrey, Liyen Loh, James McCluskey, Carolien E. van de Sandt, Nicholas A Gherardin, E. Kaitlynn Allen, Paul G. Thomas, Sidonia B G Eckle, Martha Lappas, Thomas Loudovaris, Ludivine Grzelak, Jane Crowe, Kylie M. Quinn, Jeremy Chase Crawford, Hui-Fern Koay, Sneha Sant, Katie L. Flanagan, Nicola L. Bird, Marcela de Lima Moreira, Jamie Rossjohn
Publikováno v:
Journal of immunology (Baltimore, Md., 204(5), 1119-1133. American Association of Immunologists
The Journal of Immunology
The Journal of Immunology
Mucosal-associated invariant T (MAIT) cells are important for immune responses against microbial infections. Although known to undergo marked numerical changes with age in humans, our understanding of how MAIT cells are altered during different phase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c89e19a9231fbf54a016acadd9d1b6
https://doi.org/10.4049/jimmunol.1900774
https://doi.org/10.4049/jimmunol.1900774
Autor:
Nicola L Bird, Matthew R Olson, Aeron C Hurt, Christine M Oshansky, Ding Yuan Oh, Patrick C Reading, Brendon Y Chua, Yilun Sun, Li Tang, Andreas Handel, David C Jackson, Stephen J Turner, Paul G Thomas, Katherine Kedzierska
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129768 (2015)
CD8(+) T cells directed against conserved viral regions elicit broad immunity against distinct influenza viruses, promote rapid virus elimination and enhanced host recovery. The influenza neuraminidase inhibitor, oseltamivir, is prescribed for therap
Externí odkaz:
https://doaj.org/article/7e29b53b203047a28b74b60edca55995
Autor:
Lukasz Kedzierski, Edmond M Linossi, Tatiana B Kolesnik, E Bridie Day, Nicola L Bird, Benjamin T Kile, Gabrielle T Belz, Donald Metcalf, Nicos A Nicola, Katherine Kedzierska, Sandra E Nicholson
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004134 (2014)
Suppressor of cytokine signaling (SOCS) proteins are key regulators of innate and adaptive immunity. There is no described biological role for SOCS4, despite broad expression in the hematopoietic system. We demonstrate that mice lacking functional SO
Externí odkaz:
https://doaj.org/article/e74a61e58a7f4bfba5811da5416a7bf4
Autor:
Sophie A. Valkenburg, Vanessa Venturi, Thurston H. Y. Dang, Nicola L. Bird, Peter C. Doherty, Stephen J. Turner, Miles P. Davenport, Katherine Kedzierska
Publikováno v:
PLoS Pathogens, Vol 8, Iss 3 (2012)
Externí odkaz:
https://doaj.org/article/fbae04aeee4a471a83509c903b822788
Autor:
Sophie A Valkenburg, Vanessa Venturi, Thurston H Y Dang, Nicola L Bird, Peter C Doherty, Stephen J Turner, Miles P Davenport, Katherine Kedzierska
Publikováno v:
PLoS Pathogens, Vol 8, Iss 2, p e1002544 (2012)
The elderly are particularly susceptible to influenza A virus infections, with increased occurrence, disease severity and reduced vaccine efficacy attributed to declining immunity. Experimentally, the age-dependent decline in influenza-specific CD8(+
Externí odkaz:
https://doaj.org/article/6fa5a2ce4ae94b5194f76687d579ccd1
Autor:
Thi H. O. Nguyen, Sophie A. Valkenburg, Anthony Jaworowski, Emma J. Grant, Marios Koutsakos, E. Bridie Clemens, Nicola L. Bird, Jane Crowe, Martha Lappas, Sneha Sant, Stephanie Gras, Liyen Loh, Katherine Kedzierska
Publikováno v:
Journal of Leukocyte Biology. 103:321-339
Influenza epidemics lead to severe illness, life-threatening complications, and deaths, especially in the elderly. As CD8+ T cells are associated with rapid recovery from influenza, we investigated the effects of aging on antigen-specific CD8+ T cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7564767a8a8f1e4944d466bd6917e29f
https://doi.org/10.1189/jlb.5ma0517-207r
https://doi.org/10.1189/jlb.5ma0517-207r
Maintenance of the EBV-specific CD8+ TCRαβ repertoire in immunosuppressed lung transplant recipients
Autor:
Paul G. Thomas, Nicole A. Mifsud, Tom Kotsimbos, Thi H. O. Nguyen, Katherine Kedzierska, Nicola L. Bird, John J. Miles, Emma J. Grant
Publikováno v:
Immunology and Cell Biology
Epstein-Barr virus (EBV) is one of the most common viruses in humans, capable of causing life-threatening infections and cancers in immunocompromised individuals. Although CD8+ T cells provide key protection against EBV, the persistence and dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62284ab1b3f4bcf7a1fc6023380c0a7d
http://europepmc.org/articles/PMC5214975
http://europepmc.org/articles/PMC5214975
Autor:
Ashley Mansell, Patricia Hoi Yee Lee, Lorena E. Brown, Charley Mackenzie-Kludas, Julie L. McAuley, Nicola L. Bird, Katherine Kedzierska
Publikováno v:
Immunology and Cell Biology
Expression of the viral virulence protein PB1-F2 during infection has been linked to NLRP3 inflammasome complex activation in macrophages and induction of early inflammatory events enhancing immunopathology during influenza disease. We sought to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ba25b74d2d4b5c07338acab2998a424
https://doi.org/10.1038/icb.2015.115
https://doi.org/10.1038/icb.2015.115
Autor:
Gabrielle T. Belz, E. Bridie Clemens, Katherine Kedzierska, Nicos A. Nicola, Lukasz Kedzierski, Sandra E. Nicholson, Nicola L. Bird, Benjamin T. Kile
Publikováno v:
Immunology & Cell Biology. 93:909-913
Suppressor of cytokine signaling (SOCS) proteins are key regulators of innate and adaptive immunity. Mice lacking functional SOCS4 are hypersusceptible to primary infection with influenza A virus (IAV), displaying dysregulated pro-inflammatory cytoki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b66e05f707a3ac00e0e9b21a3fe55eb3
https://doi.org/10.1038/icb.2015.55
https://doi.org/10.1038/icb.2015.55