Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicola L Diny"'
Autor:
Xuezhou Hou, Guobao Chen, William Bracamonte-Baran, Hee Sun Choi, Nicola L. Diny, Jungeun Sung, David Hughes, Taejoon Won, Megan Kay Wood, Monica V. Talor, David Joel Hackam, Karin Klingel, Giovanni Davogustto, Heinrich Taegtmeyer, Isabelle Coppens, Jobert G. Barin, Daniela Čiháková
Publikováno v:
Cell Reports, Vol 28, Iss 1, Pp 172-189.e7 (2019)
Summary: Two types of monocytes, Ly6Chi and Ly6Clo, infiltrate the heart in murine experimental autoimmune myocarditis (EAM). We discovered a role for cardiac fibroblasts in facilitating monocyte-to-macrophage differentiation of both Ly6Chi and Ly6Cl
Externí odkaz:
https://doaj.org/article/b6b5be67eb354a43a097237f7256ed86
Autor:
Xianghui Chen, Guiqin Wang, Yu Zhang, Margaret Dayhoff-Brannigan, Nicola L Diny, Mingjun Zhao, Ge He, Cierra N Sing, Kyle A Metz, Zachary D Stolp, Abdel Aouacheria, Wen-Chih Cheng, J Marie Hardwick, Xinchen Teng
Publikováno v:
PLoS Genetics, Vol 14, Iss 8, p e1007592 (2018)
Yeast WHI2 was originally identified in a genetic screen for regulators of cell cycle arrest and later suggested to function in general stress responses. However, the function of Whi2 is unknown. Whi2 has predicted structure and sequence similarity t
Externí odkaz:
https://doaj.org/article/6da71e8946194a80a1079b79bc8b4a3e
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Eosinophils are multifunctional granulocytes that contribute to initiation and modulation of inflammation. Their role in asthma and parasitic infections has long been recognized. Growing evidence now reveals a role for eosinophils in autoimmune disea
Externí odkaz:
https://doaj.org/article/046897f436d14fdfb437a30b16a5d1e9
Autor:
Ari Waisman, Xuezhou Hou, Heinrich Taegtmeyer, Kai Fu, Nicola L. Diny, Yue Liu, William Bracamonte-Baran, Daniela Cihakova, Hernan G. Vasquez, Fengyi Wan, Simon J. Conway, Giovanni Davogustto, Guobao Chen, Monica V. Talor, O. Howard Frazier
Publikováno v:
European Journal of Immunology. 48:1522-1538
The causative effect of GM-CSF produced by cardiac fibroblasts to development of heart failure has not been shown. We identified the pathological GM-CSF-producing cardiac fibroblast subset and the specific deletion of IL-17A signaling to these cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07bc35f1d9f18ae6e7cb07918045c4a1
https://doi.org/10.1002/eji.201847583
https://doi.org/10.1002/eji.201847583
Autor:
Djahida Bedja, Monica V. Talor, Guobao Chen, Daniel A. Peterson, Ashley B. Cardamone, Elizabeth Gebremariam, Daniela Cihakova, Julie Schaub, Lei Wu, Hee Sun Choi, Xuezhou Hou, SuFey Ong, Jobert G. Barin, Nicola L. Diny, Noel R. Rose
Publikováno v:
Experimental and Molecular Pathology. 103:141-152
The extensive, diverse communities that constitute the microbiome are increasingly appreciated as important regulators of human health and disease through inflammatory, immune, and metabolic pathways. We sought to elucidate pathways by which microbio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e858e2ade94d175ea67dc5d4aab8272
https://doi.org/10.1016/j.yexmp.2017.08.003
https://doi.org/10.1016/j.yexmp.2017.08.003
Autor:
Jobert G. Barin, Noel R. Rose, Djahida Bedja, Nisha A. Gilotra, SuFey Ong, Allison G. Hays, Monica V. Talor, Isabelle Coppens, Nicola L. Diny, G. Christian Baldeviano, Daniela Cihakova
Publikováno v:
The Journal of Experimental Medicine
Diny et al. report a pathogenic role for eosinophils in autoimmune myocarditis and dilated cardiomyopathy. Eosinophils are required for progression of myocarditis to dilated cardiomyopathy and drive severe disease when present in large numbers. Activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03a3fd5b6b83ebaeb52581e1b8490c5d
https://doi.org/10.1084/jem.20161702
https://doi.org/10.1084/jem.20161702
Autor:
Guobao Chen, Noel R. Rose, Xuezhou Hou, Julie Schaub, Karin Klingel, Jobert G. Barin, Daniela Cihakova, Monica V. Talor, Stuart D. Russell, Nicola L. Diny
Publikováno v:
European Journal of Immunology. 46:2749-2760
Cardiac manifestations are a major cause of morbidity and mortality in patients with eosinophil-associated diseases. Eosinophils are thought to play a pathogenic role in myocarditis. We investigated the pathways that recruit eosinophils to the heart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::650d2a459560233c1a3665840161f47e
https://doi.org/10.1002/eji.201646557
https://doi.org/10.1002/eji.201646557
Autor:
Xuezhou Hou, Daniela Cihakova, Nathan K. Archer, Matthew Hoyer, Lloyd S. Miller, Noel R. Rose, Julie Schaub, Elizabeth Gebremariam, Meghan F. Davis, Monica V. Talor, Jobert G. Barin, Nicola L. Diny
Publikováno v:
The American Journal of Pathology. 186:2337-2352
Infections with Staphylococcus aureus are a continuing and growing problem in community and hospital settings. Preclinical animal modeling of S. aureus relies on experimental infection, which carries some limitations. We describe here a novel, sponta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::701d23ad2aa2ce71cf7fad4d6d145d2d
https://doi.org/10.1016/j.ajpath.2016.07.001
https://doi.org/10.1016/j.ajpath.2016.07.001
Autor:
Monica V. Talor, Xuezhou Hou, Nicola L. Diny, Lei Wu, SuFey Ong, Noel R. Rose, Daniela Cihakova, Jobert G. Barin
Publikováno v:
European Journal of Immunology. 46:582-592
Using a mouse model of experimental autoimmune myocarditis (EAM), we showed for the first time that IL-23 stimulation of CD4(+) T cells is required only briefly at the initiation of GM-CFS-dependent cardiac autoimmunity. IL-23 signal, acting as a swi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39954dbe85d920f599e88741f9348dd9
https://doi.org/10.1002/eji.201545924
https://doi.org/10.1002/eji.201545924
Autor:
Xuezhou Hou, Daniela Cihakova, Isabelle Coppens, Heinrich Taegtmeyer, Jungeun Sung, Hee Sun Choi, David J. Hackam, Giovanni Davogustto, Nicola L. Diny, Jobert G. Barin, William Bracamonte-Baran, Monica V. Talor, Karin Klingel, Guobao Chen
Publikováno v:
SSRN Electronic Journal.
Two types of monocytes, Ly6Chi and Ly6Clo, infiltrate the heart in murine experimental autoimmune myocarditis (EAM). We discovered a previously unappreciated role for cardiac fibroblasts in facilitating both Ly6Chi and Ly6Clo monocyte-to-macrophage d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73501a6a594ac676f891602b8d37e49f
https://doi.org/10.2139/ssrn.3272232
https://doi.org/10.2139/ssrn.3272232