Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nicola Jordan-Mahy"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Apigenin is a dietary polyphenol found abundantly in fruit and vegetables, which sensitizes leukaemia cells to topoisomerase inhibitor agents (e.g., etoposide), and alkylating agents (e.g., cyclophosphamide), reducing ATP levels and inducing
Externí odkaz:
https://doaj.org/article/950da4487cd14bb28249f4c7439a4817
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Programmed death-ligand 1 (PD-L1) is an immune checkpoint inhibitor that binds to its receptor PD-1 expressed by T cells and other immune cells to regulate immune responses; ultimately preventing exacerbated activation and autoimmunity. Many tumors e
Externí odkaz:
https://doaj.org/article/f65c4066da144be3989cafa99f077a9e
Apigenin is a dietary polyphenol found abundantly in fruit and vegetables. It has been shown to sensitize acute lymphoid and myeloid leukaemia cells to topoisomerase inhibitor agents (e.g., etoposide), and alkylating agents (e.g., cyclophosphamide),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e25f56776152f66504c43c3faf248966
https://doi.org/10.21203/rs.3.rs-1081612/v1
https://doi.org/10.21203/rs.3.rs-1081612/v1
Publikováno v:
Scientific reports. 12(1)
Apigenin is a dietary polyphenol found abundantly in fruit and vegetables, which sensitizes leukaemia cells to topoisomerase inhibitor agents (e.g., etoposide), and alkylating agents (e.g., cyclophosphamide), reducing ATP levels and inducing apoptosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a127e1664930f3aa7e21d937c26a9f01
https://pubmed.ncbi.nlm.nih.gov/35614109
https://pubmed.ncbi.nlm.nih.gov/35614109
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
The in vitro study of the pathogenesis of inflammatory bowel disease (IBD) requires a cell model which closely reflects the characteristics of the in vivo intestinal epithelium. This study aimed to investigate the application of L-pNIPAM hydrogel as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebd62dbef0928ad6f9b42817e827e292
http://link.springer.com/article/10.1038/s41598-019-38524-8
http://link.springer.com/article/10.1038/s41598-019-38524-8
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology
Frontiers in Immunology
Programmed death-ligand 1 (PD-L1) is an immune checkpoint inhibitor that binds to its receptor PD-1 expressed by T cells and other immune cells to regulate immune responses; ultimately preventing exacerbated activation and autoimmunity. Many tumors e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b448943924bcba51f6f74ba153a9e21f
https://shura.shu.ac.uk/27486/9/Leyland-ExtrinsicIntrinsicRoles(VoR).pdf
https://shura.shu.ac.uk/27486/9/Leyland-ExtrinsicIntrinsicRoles(VoR).pdf
Publikováno v:
Biomaterials science. 8(8)
A number of biological tissues have been reported as behaving in an auxetic manner, defined by a negative Poisson's ratio. This describes the deformation of tissue which expands in the axial and the transverse directions simultaneously while under un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4b8ee635e6908a207b47f8c611f21f
https://pubmed.ncbi.nlm.nih.gov/32215398
https://pubmed.ncbi.nlm.nih.gov/32215398
Publikováno v:
Cancer Research. 81:2988-2988
Tumorigenic expression of programmed death-ligand 1 (PD-L1) and its receptor PD-1 is found in many cancers, though the intrinsic roles of these proteins and how immunotherapy treatment may affect these pathways needs to be fully explored across human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::816692ac4079c49ec094c1cb39d11dfd
https://doi.org/10.1158/1538-7445.am2021-2988
https://doi.org/10.1158/1538-7445.am2021-2988
Publikováno v:
Acta Biomaterialia. 62:128-143
The human intestinal cell lines: Caco-2 and HT29-MTX cells have been used extensively in 2D and 3D cell cultures as simple models of the small intestinal epithelium in vitro. This study aimed to investigate the potential of three hydrogel scaffolds t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ed8db774e25db3f6bb75c989b337250
https://doi.org/10.1016/j.actbio.2017.08.035
https://doi.org/10.1016/j.actbio.2017.08.035
Publikováno v:
Oncotarget
Polyphenols have been previously shown to sensitize leukemia cell lines to topoisomerase inhibitors. Here, we assess the effects of five polyphenols when used alone and in combination with antimetabolites: methotrexate, 6-mercaptopurine and 5-fluorou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328a3e7b47a39a9ecafb2f349cd90990
http://europepmc.org/articles/PMC5739607
http://europepmc.org/articles/PMC5739607