Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Nicola J. Rutherford"'
Autor:
Zachary A. Sorrentino, Yuxing Xia, Cory Funk, Cara J. Riffe, Nicola J. Rutherford, Carolina Ceballos Diaz, Amanda N. Sacino, Nathan D. Price, Todd E. Golde, Benoit I. Giasson, Paramita Chakrabarty
Publikováno v:
Neurobiology of Disease, Vol 120, Iss , Pp 98-106 (2018)
Mechanisms underlying α-synuclein (αSyn) mediated neurodegeneration are poorly understood. Intramuscular (IM) injection of αSyn fibrils in human A53T transgenic M83+/− mice produce a rapid model of α-synucleinopathy with highly predictable onse
Externí odkaz:
https://doaj.org/article/b6896a39637443f99f13c29f3c8590e8
Autor:
Zachary A. Sorrentino, Mieu M.T. Brooks, Vincent Hudson, Nicola J. Rutherford, Todd E. Golde, Benoit I. Giasson, Paramita Chakrabarty
Publikováno v:
Molecular Neurodegeneration, Vol 12, Iss 1, Pp 1-16 (2017)
Abstract Background Prionoid transmission of α-synuclein (αSyn) aggregates along neuroanatomically connected projections is posited to underlie disease progression in α-synucleinopathies. Here, we specifically wanted to study whether this prionoid
Externí odkaz:
https://doaj.org/article/c9e8970133d44a9699752cbf6fee3a81
Publikováno v:
American Journal of Clinical Pathology. 154:494-498
ObjectivesThe US Food and Drug Administration requires donated blood to be tested for various infectious diseases to ensure safety and purity. However, testing for hemoglobin variants is not required, despite reported occurrences of hemoglobin varian
Publikováno v:
Clinical Biochemistry. 68:50-54
Objectives Fluoroquinolone antibiotics are commonly used in the treatment of infections and have previously been confirmed to cross-react with previous generations of opiates immunoassays . In this work we evaluated the cross-reactivity of the three
Publikováno v:
American journal of clinical pathology. 154(5)
Objectives Voxelotor was recently approved for use in the United States as a treatment for sickle cell disease (SCD) and has been shown to interfere with the quantitation of hemoglobin (Hb) S percentage. This study aimed to determine the effect of vo
Autor:
Susan M. Abdel-Rahman, Sami Albeiroti, D. Adam Algren, Justin Arnold, Amit Bansal, Adrian Baron, Melissa Beals, Marianne Benyon, Valkal Bhatt, Caren J. Blacker, Geza S. Bodor, Diane M. Boland, Vincent Buggs, Brian Capron, Dean C. Carlow, Amanda Chandler, Michael R. Christian, Uwe Christians, Jennifer M. Colby, Steven W. Cotten, Fiona Couper, Todd Crane, Kristine R. Crews, Saswati Das, Amitava Dasgupta, Brehon Davis, Sarah R. Delaney, Sridevi Devaraj, Mary H. Dudley (retired), Julia E. Esswein, Sheng Feng, Angela M. Ferguson, C. Clinton Frazee, Deborah French, Uttam Garg, Cindy George, Roy G. Gerona, Bruce A. Goldberger, Aaron Guinn, Lindsey J. Haldiman, Ara Hall, Yong Y. Han, Paul R. Hess, Andrea Ho, Tiffany Hollenbeck, Jessica A. Hvozdovich, Gregory Janis, Paul J. Jannetto, Jeffrey Jentzen, Leo Johnson, Kamisha L. Johnson-Davis, Heath A. Jolliff, Patricia M. Jones, Deven Juneja, Erin Kaleta, Amy B. Karger, Jaswinder Kaur, Kathleen A. Kelly, Hema Ketha, Jeff Knoblauch, Mikail Kraft, Matthew D. Krasowski, Robert Krumsick, Patrick B. Kyle, Jennifer A. Lowry, Andrew W. Lyon, Martha E. Lyon, Michael C. Malone, Michael M. Mbughuni, Christopher McCudden, Cornelia McDonald, Stacy E.F. Melanson, Chelsea Milito, Ross J. Miller, Alejandro R. Molinelli, Riley Murphy, Hari Nair, Vijayalakshmi Nandakumar, Prashant Nasa, John D. Nolen, Mushal Noor, John O. Ogunbileje, Anthony O. Okorodudu, Gabor Oroszi, Jayson V. Pagaduan, Wesley Palatnick, Khushbu Patel, Heather A. Paul, Amadeo Pesce, Mark Petersen, Brianna Peterson, Diane C. Peterson, Robert B. Pietak, Zoë Piggott, Bheemraj Ramoo, Alexandra Rapp, Jason L. Robinson, Cecilia M. Rosales, Nicola J. Rutherford-Parker, S.M. Hossein Sadrzadeh, Umar Salimi, Bjoern Schniedewind, Michael Scordo, Jesse Seegmiller, Hila Shaim, Leslie M. Shaw, Devin L. Shrock, Sarah Smiley, Christine L.H. Snozek, Kimia Sobhani, Alina G. Sofronescu, Heather M. Stieglitz, Roger W. Stone, Frederick G. Strathmann, Zengliu Su, Theresa Swift, Marius C. Tarau, Milton Tenenbein, Ruben Thanacoody, Marita Thompson, Stephen L. Thornton, Manoj Tyagi, Hana Vakili, Judith Sebestyen VanSickle, Ping Wang, Milad Webb, Elizabeth Wehner, Darcy Weidemann, Megan Weitzel, Meagan L. Wisniewski, Brian Wright, Fang Wu, Yifei Yang, Kiang-Teck J. Yeo, Paul E. Young, Y. Victoria Zhang, Viktor A. Zherebitskiy, Yusheng Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76458f16eed1034cb3ffc05347a5cec0
https://doi.org/10.1016/b978-0-12-815846-3.00027-2
https://doi.org/10.1016/b978-0-12-815846-3.00027-2
A 24-year-old male with a history of dizziness and syncope presented to the emergency department via ambulance for the fourth time in 36 hours. His medical history is significant for postural orthostatic tachycardia and factitious disorder. Upon exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9411fddfdd16d18d03f9c6f566d72677
https://doi.org/10.1016/b978-0-12-815846-3.00087-9
https://doi.org/10.1016/b978-0-12-815846-3.00087-9
Publikováno v:
The Journal of Applied Laboratory Medicine. 3:140-143
A 29-year-old Saudi Arabian male with known sickle cell disease presented to the hematology clinic at Vanderbilt University Medical Center for follow-up and disease management. The patient had a complex past medical history including frequent pain cr
Autor:
Mieu Brooks, Nicola J. Rutherford, Kimberly-Marie M. Gorion, Benoit I. Giasson, Cara J. Riffe, Jasie K. Howard, Jess-Karan S. Dhillon
Publikováno v:
Neuroscience Letters. 661:114-120
Neurofilaments are a major component of the axonal cytoskeleton in neurons and have been implicated in a number of neurodegenerative diseases due to their presence within characteristic pathological inclusions. Their contributions to these diseases a
Autor:
Nicola J Rutherford, Yong-Jie Zhang, Matt Baker, Jennifer M Gass, Nicole A Finch, Ya-Fei Xu, Heather Stewart, Brendan J Kelley, Karen Kuntz, Richard J P Crook, Jemeen Sreedharan, Caroline Vance, Eric Sorenson, Carol Lippa, Eileen H Bigio, Daniel H Geschwind, David S Knopman, Hiroshi Mitsumoto, Ronald C Petersen, Neil R Cashman, Mike Hutton, Christopher E Shaw, Kevin B Boylan, Bradley Boeve, Neill R Graff-Radford, Zbigniew K Wszolek, Richard J Caselli, Dennis W Dickson, Ian R Mackenzie, Leonard Petrucelli, Rosa Rademakers
Publikováno v:
PLoS Genetics, Vol 4, Iss 9, p e1000193 (2008)
The TAR DNA-binding protein 43 (TDP-43) has been identified as the major disease protein in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin inclusions (FTLD-U), defining a novel class of neurodegenerative cond
Externí odkaz:
https://doaj.org/article/3cae87e0864343239646260c2e500bfe