Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nicola J. Kuiper"'
Autor:
Timothy Hopkins, Karina T. Wright, Nicola J. Kuiper, Sally Roberts, Paul Jermin, Peter Gallacher, Jan Herman Kuiper
Publikováno v:
Cells, Vol 10, Iss 8, p 1903 (2021)
Chondrocyte-based cartilage repair strategies, such as articular chondrocyte implantation, are widely used, but few studies addressed the communication between native subchondral bone cells and the transplanted chondrocytes. An indirect co-culture mo
Externí odkaz:
https://doaj.org/article/993a17b4a68146efaa1178145b9be12c
Autor:
Rebecca L Davies, Nicola J Kuiper
Publikováno v:
Bioengineering, Vol 6, Iss 1, p 22 (2019)
Articular cartilage is composed of chondrons within a territorial matrix surrounded by a highly organized extracellular matrix comprising collagen II fibrils, proteoglycans, glycosaminoglycans, and non-collagenous proteins. Damaged articular cartilag
Externí odkaz:
https://doaj.org/article/af9b4b83e4f84f179356f6e0fc9ba9bc
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133745 (2015)
Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progressive cellul
Externí odkaz:
https://doaj.org/article/bcc6e6d001a146699f5c694d09d85540
Autor:
Josep Sulé-Suso, Ying Yang, Abigail V. Rutter, Nicola J. Kuiper, H A Owida, Gianfelice Cinque
Publikováno v:
The Analyst. 143:5979-5986
Isolated and monolayer expanded chondrocytes are not the ideal cell form to produce a cartilage matrix. In articular cartilage, each chondrocyte is surrounded by a 2-4 μm thick collagen VI-rich pericellular matrix (PCM) forming a chondron. Freshly e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be77d6679135b541b831b05650bfcc5d
https://doi.org/10.1039/c8an01272e
https://doi.org/10.1039/c8an01272e
Publikováno v:
Histochemistry and Cell Biology. 148:625-638
Adult articular chondrocytes are surrounded by a pericellular matrix (PCM) to form a chondron. The PCM is rich in hyaluronan, proteoglycans, and collagen II, and it is the exclusive location of collagen VI in articular cartilage. Collagen VI anchors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3721c997784bf9a17bc4fe9f3f60a676
https://doi.org/10.1007/s00418-017-1602-4
https://doi.org/10.1007/s00418-017-1602-4
Autor:
Nicola J. Kuiper, Rebecca L Davies
Publikováno v:
Bioengineering, 6(1):22
Bioengineering, Vol 6, Iss 1, p 22 (2019)
Bioengineering
Bioengineering, Vol 6, Iss 1, p 22 (2019)
Bioengineering
Articular cartilage is composed of chondrons within a territorial matrix surrounded by a highly organized extracellular matrix comprising collagen II fibrils, proteoglycans, glycosaminoglycans, and non-collagenous proteins. Damaged articular cartilag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87720208748edad55c6ff90fabc8fb9d
Autor:
Karina T. Wright, Nicola J. Kuiper, James B. Richardson, J.G. Sykes, Sally Roberts, Jan Herman Kuiper
Publikováno v:
European Cells & Materials, Vol 35, Pp 255-267 (2018)
High hopes have been pinned on regenerative medicine strategies in order to prevent the progression of cartilage damage to osteoarthritis, particularly by autologous chondrocyte implantation (ACI). The loss of chondrocyte phenotype during in vitro mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c546f4dc6886794c5cc86652fbd90ef5
Publikováno v:
Journal of Biomaterials and Tissue Engineering. 4:162-171
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::121eacea795cbef0dae087fd86ee2a5d
https://doi.org/10.1166/jbt.2014.1145
https://doi.org/10.1166/jbt.2014.1145
Autor:
Sarah H. Cartmell, Richard A. Booth, Louise Parsons Chini, Shailesh Naire, Sarah L. Waters, Clare Bailey, Rosemary J. Dyson, Julian B. Chaudhuri, Robert J. Whittaker, Vipin Michael, Linda Cummings, Zimei Rong, Lina Mawasse, Marianne J. Ellis, Sevil Payvandi, Hannah Woollard, Nicola J. Kuiper
We develop a simple mathematical model for forced flow of culture medium through a porous scaffold in a tissue- engineering bioreactor. Porous-walled hollow fibres penetrate the scaffold and act as additional sources of culture medium. The model, bas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cd2d3e6f26cdbfd047ba25cf586cb67
https://ora.ox.ac.uk/objects/uuid:2da3a45b-51c4-4637-8735-08c0128b7057
https://ora.ox.ac.uk/objects/uuid:2da3a45b-51c4-4637-8735-08c0128b7057
Publikováno v:
The Knee. 24(1)
Background\ud Autologous chondrocyte implantation (ACI) has been used to treat cartilage defects in thousands of patients worldwide with good clinical effectiveness 10–20 years after implantation. Information concerning the quality of the repair ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f2e253861b7368f9727baefc138c6e
https://pubmed.ncbi.nlm.nih.gov/27773574
https://pubmed.ncbi.nlm.nih.gov/27773574