A major locus confers triclabendazole resistance in Fasciola hepatica and shows dominant inheritance.

Autor: Nicola J Beesley, Krystyna Cwiklinski, Katherine Allen, Rebecca C Hoyle, Terry W Spithill, E James La Course, Diana J L Williams, Steve Paterson, Jane E Hodgkinson

Publikováno v: PLoS Pathogens, Vol 19, Iss 1, p e1011081 (2023)

Fasciola hepatica infection is responsible for substantial economic losses in livestock worldwide and poses a threat to human health in endemic areas. The mainstay of control in livestock and the only drug licenced for use in humans is triclabendazol

Externí odkaz: https://doaj.org/article/47274f3eaf804c1e88d60db0e5999538

Patterns of Fasciola hepatica infection in Danish dairy cattle: implications for on-farm control of the parasite based on different diagnostic methods

Autor: Nao Takeuchi-Storm, Matthew J. Denwood, Stig Milan Thamsborg, Anna-Sofie Stensgaard, Heidi L. Enemark, Diana L. Williams, Mita E. Sengupta, Jane E. Hodgkinson, Nicola J. Beesley, Heidi Huus Petersen

Publikováno v: Parasites & Vectors, Vol 11, Iss 1, Pp 1-18 (2018)
Parasites & Vectors
Takeuchi-Storm, N, Denwood, M, Petersen, H H, Enemark, H L, Stensgaard, A S, Sengupta, M E, Beesley, N J, Hodgkinson, J, Williams, D & Thamsborg, S M 2018, ' Patterns of Fasciola hepatica infection in Danish dairy cattle: Implications for on-farm control of the parasite based on different diagnostic methods ', Parasites and Vectors, vol. 11, no. 1, 674 . https://doi.org/10.1186/s13071-018-3248-z
Takeuchi-Storm, N, Denwood, M, Petersen, H H, Enemark, H L, Stensgaard, A-S, Sengupta, M E, Beesley, N J, Hodgkinson, J, Williams, D & Thamsborg, S M 2018, ' Patterns of Fasciola hepatica infection in Danish dairy cattle : implications for on-farm control of the parasite based on different diagnostic methods ', Parasites & Vectors, vol. 11, 674 . https://doi.org/10.1186/s13071-018-3248-z

Background Bovine fasciolosis is an economically important livestock disease in Europe, and represents a particular challenge for organic farms, where cattle are grazed extensively and the use of anthelmintic is limited. A two-year longitudinal study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7faddb7d5c0f6d124c0145a1d9f25a26
http://link.springer.com/article/10.1186/s13071-018-3248-z

Refugia and anthelmintic resistance: concepts and challenges

Autor: Collette Britton, Roz Laing, Eric R. Morgan, Stephen R. Doyle, Barbara K. Mable, Neil Sargison, Jamie C. Prentice, Vanessa O. Ezenwa, Ray M. Kaplan, Jennifer McIntyre, Andy Fenton, Jane E. Hodgkinson, Catherine E. Milne, Sue B. Howell, Eileen Devaney, Thomas A. Morrison, Diana L. Williams, Louise Matthews, Andrew W. Park, Simon A. Babayan, Fiona Kenyon, Steve Paterson, Nicola J. Beesley, Adrian J. Wolstenholme, Umer Chaudhry

Publikováno v: Devaney, E, Matthews, L, Milne, C, Howell, S, McIntyre, J, Ezenwa, V, Babayan, S A, Mable, B, Doyle, S, Morgan, E, Wiliams, D, Laing, R, Morrison, T, Britton, C, Kenyon, F, Caplan, R, Paterson, S, Beesley, N, Chaudhry, U, Fenton, A C, Hodgkinson, J E, Sargison, N, Prentice, J, Wolstenholme, A & Park, A W 2019, ' Refugia and anthelmintic resistance: concepts and challenges ', International Journal for Parasitology: Drugs and Drug Resistance . https://doi.org/10.1016/j.ijpddr.2019.05.001
International Journal for Parasitology: Drugs and Drug Resistance
Hodgkinson, J E, Kaplan, R M, Kenyon, F, Morgan, E R, Park, A W, Paterson, S, Babayan, S A, Beesley, N J, Britton, C, Chaudhry, U, Doyle, S R, Ezenwa, V O, Fenton, A, Howell, S B, Laing, R, Mable, B K, Matthews, L, McIntyre, J, Milne, C E, Morrison, T A, Prentice, J C, Sargison, N D, Williams, D J L, Wolstenholme, A J & Devaney, E 2019, ' Refugia and anthelmintic resistance: Concepts and challenges ', International Journal for Parasitology: Drugs and Drug Resistance, vol. 10, pp. 51-57 . https://doi.org/10.1016/j.ijpddr.2019.05.001
International Journal for Parasitology: Drugs and Drug Resistance, Vol 10, Iss, Pp 51-57 (2019)

Anthelmintic resistance is a threat to global food security. In order to alleviate the selection pressure for resistance and maintain drug efficacy, management strategies increasingly aim to preserve a proportion of the parasite population in ‘refu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5a07995bf49ab08d2d951117cf1147b
https://eprints.gla.ac.uk/187032/1/187032.pdf