Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nicola J Weston-Bell"'
Autor:
Nicola J Weston-Bell, Will Tapper, Jane Gibson, Dean Bryant, Yurany Moreno, Melford John, Sarah Ennis, Hanneke C Kluin-Nelemans, Andrew R Collins, Surinder S Sahota
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149162 (2016)
In classic Hairy cell leukaemia (HCLc), a single case has thus far been interrogated by whole exome sequencing (WES) in a treatment naive patient, in which BRAF V(600)E was identified as an acquired somatic mutation and confirmed as occurring near-un
Externí odkaz:
https://doaj.org/article/d914e813f99e407b83e44dd669a7a407
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86556 (2014)
A functional B-cell receptor (BCR) is critical for survival of normal B-cells, but whether it plays a comparable role in B-cell malignancy is as yet not fully delineated. Typical Hairy Cell Leukemia (HCL) is a rare B-cell tumor, and unique in express
Externí odkaz:
https://doaj.org/article/a84cf7112ca847a89262cb4d0246d6c9
Autor:
Luz Yurany Moreno Rueda, Dean Bryant, William J. Tapper, Nicola J. Weston-Bell, David C. Wedge, Naser Ansari-Pour, Surinder S. Sahota
Publikováno v:
Leukemia. 37:929-933
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f358969adfcae01dfd60a843f5e6c3
https://doi.org/10.1038/s41375-023-01823-1
https://doi.org/10.1038/s41375-023-01823-1
Autor:
Graham Packham, Pavel Klener, Lloyd Mackenzie, Jennifer Cross, Andrew J. Steele, Francesco Forconi, Mark Cragg, Freda K. Stevenson, Curtis Harwig, Jeremy Pettigrew, Georg Lenz, Chris T. Williamson, Laura Karydis, Nicola J. Weston-Bell, Karel Helman, Michael Svaton, Jana Karolova, Matthew J. Carter, Yohannes Gebreselassie, Johanna Richter, Lindsay D. Smith, Beatriz Valle-Argos, Elizabeth A. Lemm
Supplementary data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067d77f6406b11ba2ff53f0855ef08b2
https://doi.org/10.1158/1078-0432.22478181
https://doi.org/10.1158/1078-0432.22478181
Autor:
Johanna Richter, Jana Karolova, Yohannes Gebreselassie, Georg Lenz, Chris T. Williamson, Mark S. Cragg, Michael Svaton, Beatriz Valle-Argos, Lindsay D. Smith, Elizabeth Lemm, Nicola J. Weston-Bell, Graham Packham, Laura I. Karydis, Andrew J. Steele, Curtis Harwig, Karel Helman, Freda K. Stevenson, Pavel Klener, Matthew J. Carter, Jennifer Cross, Francesco Forconi, Lloyd F Mackenzie, Jeremy D Pettigrew
Publikováno v:
Clin Cancer Res
Purpose:PI3K signaling is a common feature of B-cell neoplasms, including chronic lymphocytic leukemia (CLL) and diffuse large B-cell lymphoma (DLBCL), and PI3K inhibitors have been introduced into the clinic. However, there remains a clear need to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e14b2de6e33034fe5f7f6794dee808d8
https://europepmc.org/articles/PMC7124891/
https://europepmc.org/articles/PMC7124891/
Autor:
Surinder S. Sahota, William J. Tapper, Dean Bryant, Li Song, Andrew Collins, Shengtao Xu, Niklas Zojer, Arnold Bolomsky, Nicola J. Weston-Bell
Publikováno v:
Blood. 132:232-235
TO THE EDITOR: A focus on defining genomic mutations at the whole population level in cancer may underestimate clonal plasticity in the tumor genome and how it generates genetic variation between individual single cells (SCs). This may have an impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08e125eb1c8803f9b2a25d03c6b8b014
https://doi.org/10.1182/blood-2018-01-829291
https://doi.org/10.1182/blood-2018-01-829291
Autor:
Luz Yurany Moreno, Niklas Zojer, R Bowden, Silvia Salatino, Surinder S. Sahota, Angelo Vacca, Dean Bryant, Nicola J. Weston-Bell, David C. Wedge, Andrew C.W. Zannettino, Naser Ansari-Pour
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 21:S72
Background Accurate measurement of heterogeneity and reconstruction of evolutionary pathways are key to decipher clonal dynamics in tumour origins. Although bulk population genetic sequencing data has been used extensively to understand the life hist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bc3c5256ad0f5f00077e4841ea5b0dd
https://doi.org/10.1016/s2152-2650(21)02195-9
https://doi.org/10.1016/s2152-2650(21)02195-9
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1623
Methods for tracking B-cell repertoires and clonal history in normal and malignant B-cells based on immunoglobulin variable region (IGV) gene analysis have developed rapidly with the advent of massive parallel next-generation sequencing (mpNGS) proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::32f17aa8b409dc7c01010f14e133815f
https://pubmed.ncbi.nlm.nih.gov/28589363
https://pubmed.ncbi.nlm.nih.gov/28589363
Publikováno v:
Methods in Molecular Biology ISBN: 9781493970940
Methods for tracking B-cell repertoires and clonal history in normal and malignant B-cells based on immunoglobulin variable region (IGV) gene analysis have developed rapidly with the advent of massive parallel next-generation sequencing (mpNGS) proto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e486ac7a3e2984687926413c39fa1ca
https://doi.org/10.1007/978-1-4939-7095-7_21
https://doi.org/10.1007/978-1-4939-7095-7_21
Autor:
Gessa Sugiyarto, Surinder S. Sahota, Francesco Forconi, Nicola J. Weston-Bell, Hanneke C. Kluin-Nelemans, Nicolaas A. Bos, Djoke Hendriks
Publikováno v:
Leukemia, 27(1), 241-245. Nature Publishing Group
Hairy cell leukemia cell lines expressing annexin A1 and displaying B-cell receptor signals characteristic of primary tumor cells lack the signature BRAF mutation to reveal unrepresentative origins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26f707ae1bbcbe316fae3e0ad350b1a
https://doi.org/10.1038/leu.2012.163
https://doi.org/10.1038/leu.2012.163