Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Nicola J Lee"'
Autor:
Ee-Cheng Khor, Bruce Fanshawe, Yue Qi, Sergei Zolotukhin, Rishikesh N Kulkarni, Ronaldo F Enriquez, Louise Purtell, Nicola J Lee, Natalie K Wee, Peter I Croucher, Lesley Campbell, Herbert Herzog, Paul A Baldock
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0148155 (2016)
Prader-Willi Syndrome (PWS), a maternally imprinted disorder and leading cause of obesity, is characterised by insatiable appetite, poor muscle development, cognitive impairment, endocrine disturbance, short stature and osteoporosis. A number of caus
Externí odkaz:
https://doaj.org/article/707580c41569469e85e0b7d18109c9b5
Autor:
Paul A Baldock, Nicola J Lee, Frank Driessler, Shu Lin, Susan Allison, Bernhard Stehrer, En-Ju D Lin, Lei Zhang, Ronald F Enriquez, Iris P L Wong, Michelle M McDonald, Matthew During, Dominique D Pierroz, Katy Slack, Yan C Shi, Ernie Yulyaningsih, Aygul Aljanova, David G Little, Serge L Ferrari, Amanda Sainsbury, John A Eisman, Herbert Herzog
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8415 (2009)
Changes in whole body energy levels are closely linked to alterations in body weight and bone mass. Here, we show that hypothalamic signals contribute to the regulation of bone mass in a manner consistent with the central perception of energy status.
Externí odkaz:
https://doaj.org/article/1c4e10f85e774d4ab672cfe858d76d32
Publikováno v:
Molecular Metabolism, Vol 76, Iss , Pp 101790- (2023)
Objective: One of leptin's main targets in the hypothalamus are neuropeptide Y (NPY) neurons, with selective deletion of leptin receptors (Lepr) specifically in Npy neurons resulting in major alterations of energy partitioning between fat and bone ma
Externí odkaz:
https://doaj.org/article/8285223c4de5485298beef3c22249ded
Publikováno v:
International Journal of Obesity. 46:1749-1758
Background/Objective Female mice are often excluded from diet-induced obesity studies as they are more resistant to the obesifying effects of a high-fat diet (HFD). However, the underlying mechanisms behind this sex disparity may actually have import
Publikováno v:
Cell Metabolism.
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 323(3)
We provide novel evidence that OGN and LCN2 decrease 120 min after ingesting a high-glucose mixed-nutrient meal in healthy adults. Acute aerobic exercise increases circulating LCN2 for up to 3-h postexercise, whereas circulating OGN remains similar t
Autor:
Chi Kin Ip, Natalie K.Y. Wee, Ronaldo F. Enriquez, Paul A. Baldock, Nicola J. Lee, Herbert Herzog, Yue Qi, Ireni Clarke
Publikováno v:
International Journal of Obesity. 44:2149-2164
Maintaining energy balance is important to ensure a healthy organism. However, energy partitioning, coordinating the distribution of sufficient energy to different organs and tissues is equally important, but the control of this process is largely un
Publikováno v:
Journal of Neuroendocrinology. 33
The central nervous system is an active and major regulator of bone structure and remodelling. Specifically, signalling within the hypothalamus has been shown to be critical to ensuring that skeletal functions align with whole body metabolic supply a
Publikováno v:
Molecular Metabolism. 59:101455
Aguti-related protein (AGRP) neurons in the arcuate nucleus of the hypothalamus (ARC), which co-express neuropeptide Y (NPY), are key regulators of feeding and energy homeostasis. However, the precise role NPY has within these neurons and the specifi
Autor:
I-Chieh J. Lee, Chi Kin Ip, Paul A. Baldock, Jac Kee Low, Herbert Herzog, Ronaldo F. Enriquez, Lei Zhang, Yue Qi, Tim Karl, Nicola J. Lee, Felicia Reed
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-19 (2018)
Nature Communications
Nature Communications
Excess caloric intake results in increased fat accumulation and an increase in energy expenditure via diet-induced adaptive thermogenesis; however, the underlying mechanisms controlling these processes are unclear. Here we identify the neuropeptide F