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pro vyhledávání: '"Nicola J Cranna"'
Publikováno v:
Cells, Vol 1, Iss 4, Pp 1182-1196 (2012)
Animal growth requires coordination of cell growth and cell cycle progression with developmental signaling. Loss of cell cycle control is extremely detrimental, with reduced cycles leading to impaired organ growth and excessive proliferation, potenti
Externí odkaz:
https://doaj.org/article/86fb75993ec34b0190614e6e3345498a
Autor:
Victoria L Chhen, James G. Ryall, Savant S Thakur, Janine L. James, Gordon S. Lynch, Nicola J Cranna, Kristy Swiderski
Publikováno v:
Cell Stress and Chaperones. 24:749-761
Skeletal myogenesis is a coordinated sequence of events associated with dramatic changes in cell morphology, motility, and metabolism, which causes cellular stress and alters proteostasis. Chaperones, such as heat-shock proteins (HSPs), play importan
Publikováno v:
Cells
Cells, Vol 1, Iss 4, Pp 1182-1196 (2012)
Cells, Vol 1, Iss 4, Pp 1182-1196 (2012)
Animal growth requires coordination of cell growth and cell cycle progression with developmental signaling. Loss of cell cycle control is extremely detrimental, with reduced cycles leading to impaired organ growth and excessive proliferation, potenti
Publikováno v:
BMC Developmental Biology
Background Ecdysone triggers transcriptional changes via the ecdysone receptor (EcR) to coordinate developmental programs of apoptosis, cell cycle and differentiation. Data suggests EcR affects cell cycle gene expression indirectly and here we identi
Autor:
Nicola J Cranna, Ross D. Hannan, Naomi C Mitchell, Jue Er Amanda Lee, Leonie M. Quinn, Jane Lin
1.1 The ecdysone pathway directs Drosophila development Ecdysone is the major steroid hormone in all holometabolous insects responsible for driving the metamorphosis of larval tissues into adult structures. During metamorphosis, ecdysone is essential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cd777f8760a3913c4e132c50e9bb568
https://doi.org/10.5772/27927
https://doi.org/10.5772/27927
Publikováno v:
Fly. 5(2)
Here we highlight our recent study, which revealed a mechanism critical for tight regulation of Drosophila myc (dmyc) transcription. Our previous work demonstrated that the RRM (RNA recognition motif) protein Half pint (Hfp) behaves as a growth and c
Autor:
Ross D. Hannan, Helena E. Richardson, Naomi C Mitchell, Timothy M. Johanson, Amanda Lee Jue Er, Nicola J Cranna, Leonie M. Quinn
Publikováno v:
Development (Cambridge, England). 137(17)
An unresolved question regarding the RNA-recognition motif (RRM) protein Half pint (Hfp) has been whether its tumour suppressor behaviour occurs by a transcriptional mechanism or via effects on splicing. The data presented here demonstrate that Hfp a
Publikováno v:
Development (Cambridge, England). 135(16)
The steroid hormone Ecdysone is crucial for developmental cell death,proliferation and morphogenesis in Drosophila. Herein, we delineate a molecular pathway linking Ecdysone signalling to cell cycle regulation in the Drosophila developing wing. We pr
Autor:
Nicola J Cranna, Leonie M. Quinn
Publikováno v:
Cell Division
Cell Division, Vol 4, Iss 1, p 3 (2009)
Cell Division, Vol 4, Iss 1, p 3 (2009)
Metamorphosis of Drosophila involves proliferation, differentiation and death of larval tissues in order to form the adult fly. The major steroid hormone implicated in the larval-pupal transition and adult tissue modelling is ecdysone. Previous revie