A systematic review of test accuracy studies evaluating molecular micro-satellite instability testing for the detection of individuals with lynch syndrome

Autor: Helen Coelho, Tracey Jones-Hughes, Tristan Snowsill, Simon Briscoe, Nicola Huxley, Ian M. Frayling, Chris Hyde

Publikováno v: BMC Cancer, Vol 17, Iss 1, Pp 1-13 (2017)

Abstract Background A systematic review was conducted to assess the diagnostic test accuracy of polymerase chain reaction (PCR)-based microsatellite instability (MSI) testing for identifying Lynch syndrome in patients with colorectal cancer (CRC). Un

Externí odkaz: https://doaj.org/article/60e8cb7d51c043d593d3f371eb4908f2

The clinical effectiveness and cost-effectiveness of cetuximab (review of technology appraisal no. 176) and panitumumab (partial review of technology appraisal no. 240) for previously untreated metastatic colorectal cancer: a systematic review and economic evaluation

Autor: Nicola Huxley, Louise Crathorne, Jo Varley-Campbell, Irina Tikhonova, Tristan Snowsill, Simon Briscoe, Jaime Peters, Mary Bond, Mark Napier, Martin Hoyle

Publikováno v: Health Technology Assessment, Vol 21, Iss 38 (2017)

Background: Colorectal cancer is the fourth most commonly diagnosed cancer in the UK after breast, lung and prostate cancer. People with metastatic disease who are sufficiently fit are usually treated with active chemotherapy as first- or second-line

Externí odkaz: https://doaj.org/article/b41c56cbf6b34b4f8fbc5d9914b1688d

Immunosuppressive therapy for kidney transplantation in children and adolescents: systematic review and economic evaluation

Autor: Marcela Haasova, Tristan Snowsill, Tracey Jones-Hughes, Louise Crathorne, Chris Cooper, Jo Varley-Campbell, Ruben Mujica-Mota, Helen Coelho, Nicola Huxley, Jenny Lowe, Jan Dudley, Stephen Marks, Chris Hyde, Mary Bond, Rob Anderson

Publikováno v: Health Technology Assessment, Vol 20, Iss 61 (2016)

Background: End-stage renal disease is a long-term irreversible decline in kidney function requiring kidney transplantation, haemodialysis or peritoneal dialysis. The preferred option is kidney transplantation followed by induction and maintenance im

Externí odkaz: https://doaj.org/article/6b5548ce11a64adaacbec4c27a8f12f8

A systematic review and economic evaluation of intraoperative tests [RD-100i one-step nucleic acid amplification (OSNA) system and Metasin test] for detecting sentinel lymph node metastases in breast cancer

Autor: Nicola Huxley, Tracey Jones-Hughes, Helen Coelho, Tristan Snowsill, Chris Cooper, Yang Meng, Chris Hyde, Rubén Mújica-Mota

Publikováno v: Health Technology Assessment, Vol 19, Iss 2 (2015)

Background: In breast cancer patients, sentinel lymph node biopsy is carried out at the same time as the removal of the primary tumour to postoperatively test with histopathology for regional metastases in the sentinel lymph node. Those patients with

Externí odkaz: https://doaj.org/article/15550f205c1a4d588293cb6817361d31

The predicted impact and cost-effectiveness of systematic testing of people with incident colorectal cancer for Lynch syndrome

Autor: James Killen, Suzanne Hughes, Michael Caruana, Robyn L. Ward, Gillian Mitchell, Alex Boussioutas, Tristan Snowsill, Veerle M.H. Coupé, Finlay A. Macrae, Yoon-Jung Kang, Ian M. Frayling, Kate T. Simms, Natalie Taylor, Nicola Huxley, Alison H. Trainer, Victoria Freeman, Karen Canfell

Publikováno v: Kang, Y-J, Killen, J, Caruana, M, Simms, K, Taylor, N, Frayling, I M, Snowsill, T, Huxley, N, Coupe, V M H, Hughes, S, Freeman, V, Boussioutas, A, Trainer, A H, Ward, R L, Mitchell, G, Macrae, F A & Canfell, K 2020, ' The predicted impact and cost-effectiveness of systematic testing of people with incident colorectal cancer for Lynch syndrome ', Medical Journal of Australia, vol. 212, no. 2, pp. 72-81 . https://doi.org/10.5694/mja2.50356
Medical Journal of Australia, 212(2), 72-81. Australasian Medical Publishing Co. Ltd

OBJECTIVES:\ud \ud To evaluate the health impact and cost-effectiveness of systematic testing for Lynch syndrome (LS) in people with incident colorectal cancer (CRC) in Australia.\ud DESIGN, SETTING, PARTICIPANTS:\ud \ud We investigated the impact of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b09c236383590a1f4820cc635503e3d