Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Nicola Gray"'
Autor:
M. Kalindu D. Rodrigo, Aarti Saiganesh, Andrew J. Hayes, Alisha M. Wilson, Jack Anstey, Janessa L. Pickering, Jua Iwasaki, Jessica Hillas, Scott Winslow, Tabitha Woodman, Philipp Nitschke, Jake A. Lacey, Karen J. Breese, Mark P. G. van der Linden, Philip M. Giffard, Steven Y. C. Tong, Nicola Gray, Keith A. Stubbs, Jonathan R. Carapetis, Asha C. Bowen, Mark R. Davies, Timothy C. Barnett
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
There is increasing evidence for metabolic processes mediating antimicrobial resistance. Here, the authors present a mechanism of sulfamethoxazole resistance in Group A Streptococcus that is dependent on acquiring end products of the host folate bios
Externí odkaz:
https://doaj.org/article/daae034efb764202a0ab48562b8281a1
Autor:
Sofina Begum, Samantha Lodge, Drew Hall, Blair Z. Johnson, Sze How Bong, Luke Whiley, Nicola Gray, Vanessa S. Fear, Mark W. Fear, Elaine Holmes, Fiona M. Wood, Jeremy K. Nicholson
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionBurn injury in children causes prolonged systemic effects on physiology and metabolism leading to increased morbidity and mortality, yet much remains undefined regarding the metabolic trajectory towards specific health outcomes.MethodsA m
Externí odkaz:
https://doaj.org/article/4f97c39a6f6c4832aeb66d011d4f13e4
Autor:
Sofina Begum, Blair Z. Johnson, Aude-Claire Morillon, Rongchang Yang, Sze How Bong, Luke Whiley, Nicola Gray, Vanessa S. Fear, Leila Cuttle, Andrew J. A. Holland, Jeremy K. Nicholson, Fiona M. Wood, Mark W. Fear, Elaine Holmes
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract A growing body of evidence supports the concept of a systemic response to non-severe thermal trauma. This provokes an immunosuppressed state that predisposes paediatric patients to poor recovery and increased risk of secondary morbidity. In
Externí odkaz:
https://doaj.org/article/bd738ef484744b0d99df495bd98504fa
Autor:
Samantha Lodge, Nathan G. Lawler, Nicola Gray, Reika Masuda, Philipp Nitschke, Luke Whiley, Sze-How Bong, Bu B. Yeap, Girish Dwivedi, Manfred Spraul, Hartmut Schaefer, Rubén Gil-Redondo, Nieves Embade, Oscar Millet, Elaine Holmes, Julien Wist, Jeremy K. Nicholson
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11614 (2023)
An integrative multi-modal metabolic phenotyping model was developed to assess the systemic plasma sequelae of SARS-CoV-2 (rRT-PCR positive) induced COVID-19 disease in patients with different respiratory severity levels. Plasma samples from 306 unva
Externí odkaz:
https://doaj.org/article/b16af06b3b43448295c5a08e4aba1177
Autor:
Faouzi Djebbari, Alexandros Rampotas, Fotios Panitsas, Wen Yuen Lim, Charlotte Lees, Ismini Tsagkaraki, Ana Rita Gomes, Steve Prideaux, Lucia Chen, Catherine Prodger, Akhil Khera, Nicola Gray, Lauren Ellis, Gina Sangha, Toby A. Eyre, Sally Moore, Jaimal Kothari, Karthik Ramasamy
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
The management of myeloma in the elderly is shifting its focus towards reducing the risk of under-treating fit patients and the risk of over-treating frail patients. Frailty assessment is required in this patient group in order to individualise treat
Externí odkaz:
https://doaj.org/article/344e1f8fae404632b69f7af78cb157d0
Publikováno v:
eJHaem, Vol 2, Iss 1, Pp 17-19 (2021)
Abstract This is a case of an unexpected and dramatic bleeding complication in a patient post‐bone marrow biopsy performed for investigation of an IgA paraprotein with the results confirming multiple myeloma. Subsequent investigations were suggesti
Externí odkaz:
https://doaj.org/article/0df1c381276446b594bcd2aea1174c4b
Autor:
Sarah Gooding, Sam W. Z. Olechnowicz, Emma V. Morris, Andrew E. Armitage, Joao Arezes, Joe Frost, Emmanouela Repapi, James R. Edwards, Neil Ashley, Craig Waugh, Nicola Gray, Erik Martinez-Hackert, Pei Jin Lim, Sant-Rayn Pasricha, Helen Knowles, Adam J. Mead, Karthik Ramasamy, Hal Drakesmith, Claire M. Edwards
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Multiple myeloma is a cancer of the bone marrow that can induce bone disease. Here, the authors profile the transcriptome of bone-lining cells and find a targetable role of bone morphogenetic protein (BMP) signalling in myeloma-induced bone-disease
Externí odkaz:
https://doaj.org/article/afce39d2e8774212826676e3142ffc40
Autor:
Javier I. Ottaviani, Reedmond Fong, Jennifer Kimball, Jodi L. Ensunsa, Nicola Gray, Anna Vogiatzoglou, Abigail Britten, Debora Lucarelli, Robert Luben, Philip B. Grace, Deborah H. Mawson, Amy Tym, Antonia Wierzbicki, A. David Smith, Nicholas J. Wareham, Nita G. Forouhi, Kay-Tee Khaw, Hagen Schroeter, Gunter G. C. Kuhnle
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Abstract Data from dietary intervention studies suggest that intake of (−)-epicatechin mediates beneficial vascular effects in humans. However, population-based investigations are required to evaluate associations between habitual intake and health
Externí odkaz:
https://doaj.org/article/586a0ec07bae48f3a405cae15704b760
Publikováno v:
Separations, Vol 9, Iss 7, p 175 (2022)
Microsamples are collections usually less than 50 µL, although all devices that we have captured as part of this review do not fit within this definition (as some can perform collections of up to 600 µL); however, they are considered microsamples t
Externí odkaz:
https://doaj.org/article/ea289f6a2e614156a0a6ee3e1b0e8400
Publikováno v:
BMJ Open Quality, Vol 9, Iss 3 (2020)
Reforming the delivery of outpatient appointments (OPA) was high on the healthcare policy agenda prior to COVID-19. The current pandemic exacerbates the financial and associated resource limitations of OPA. Videoconsulting provides a safe method of r
Externí odkaz:
https://doaj.org/article/a58dfd92b3d040f583508a93a110f82a