Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Nicola G. A. Abrescia"'
Autor:
Miguel Navarro-Oliveros, Ander Vidaurrazaga, Gabriel Soares Guerra, Donatello Castellana, Nieves Embade, Oscar Millet, Urko M. Marigorta, Nicola G. A. Abrescia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Adeno-associated viruses (AAVs) are promising gene therapy vectors, but challenges arise when treating patients with preexisting neutralizing antibodies. Worldwide seroprevalence studies provide snapshots of existing immunity in diverse popu
Externí odkaz:
https://doaj.org/article/af74058a8c144a65b4337f2f7db5b75d
Autor:
David Reguera, Pedro J. de Pablo, Nicola G. A. Abrescia, Mauricio G. Mateu, Javier Hernández-Rojas, José R. Castón, Carmen San Martín
Publikováno v:
Biophysica, Vol 3, Iss 4, Pp 598-619 (2023)
Virus particles consist of a protein coat that protects their genetic material and delivers it to the host cell for self-replication. Understanding the interplay between virus structure and function is a requirement for understanding critical process
Externí odkaz:
https://doaj.org/article/1cc7d9dd5d9243849f143867552afda0
Autor:
Peter Simmonds, Evelien M. Adriaenssens, F. Murilo Zerbini, Nicola G. A. Abrescia, Pakorn Aiewsakun, Poliane Alfenas-Zerbini, Yiming Bao, Jakub Barylski, Christian Drosten, Siobain Duffy, W. Paul Duprex, Bas E. Dutilh, Santiago F. Elena, Maria Laura García, Sandra Junglen, Aris Katzourakis, Eugene V. Koonin, Mart Krupovic, Jens H. Kuhn, Amy J. Lambert, Elliot J. Lefkowitz, Małgorzata Łobocka, Cédric Lood, Jennifer Mahony, Jan P. Meier-Kolthoff, Arcady R. Mushegian, Hanna M. Oksanen, Minna M. Poranen, Alejandro Reyes-Muñoz, David L. Robertson, Simon Roux, Luisa Rubino, Sead Sabanadzovic, Stuart Siddell, Tim Skern, Donald B. Smith, Matthew B. Sullivan, Nobuhiro Suzuki, Dann Turner, Koenraad Van Doorslaer, Anne-Mieke Vandamme, Arvind Varsani, Nikos Vasilakis
Publikováno v:
PLoS Biology, Vol 21, Iss 2 (2023)
A universal taxonomy of viruses is essential for a comprehensive view of the virus world and for communicating the complicated evolutionary relationships among viruses. However, there are major differences in the conceptualisation and approaches to v
Externí odkaz:
https://doaj.org/article/6d80a1b0283d4cc39382a2061bd9086b
Autor:
Leire Egia-Mendikute, Alexandre Bosch, Endika Prieto-Fernández, So Young Lee, Borja Jiménez-Lasheras, Ana García del Río, Asier Antoñana-Vildosola, Chiara Bruzzone, Maider Bizkarguenaga, Nieves Embade, Rubén Gil-Redondo, María Luz Martínez-Chantar, Marcos López-Hoyos, Nicola G. A. Abrescia, José M. Mato, Óscar Millet, Asís Palazón
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Egia-Mendikute et al. develop a multiplexed flow cytometric bead array to simultaneously detect antibodies reactive to three immunogenic SARS-CoV-2 proteins. More sensitive than ELISA, they detected N-reactive antibodies in COVID-19-negative individu
Externí odkaz:
https://doaj.org/article/721616baa10e46b992979a7d09ffe6af
Autor:
Soledad Stagnoli, Francesca Peccati, Sean R. Connell, Ane Martinez-Castillo, Diego Charro, Oscar Millet, Chiara Bruzzone, Asis Palazon, Ana Ardá, Jesús Jiménez-Barbero, June Ereño-Orbea, Nicola G. A. Abrescia, Gonzalo Jiménez-Osés
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Two years after its emergence, the coronavirus disease-2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) remains difficult to control despite the availability of several vaccines. The extensively glycosyl
Externí odkaz:
https://doaj.org/article/0bb70785222547e2b682896cbcf64c65
Autor:
Hani Boshra, Gema Lorenzo, Diego Charro, Sandra Moreno, Gabriel Soares Guerra, Isbene Sanchez, Joseba M. Garrido, Marivi Geijo, Alejandro Brun, Nicola G. A. Abrescia
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Schmallenberg virus (SBV), an arthropod-transmitted pathogenic bunyavirus, continues to be a threat to the European livestock industry, causing morbidity and mortality among young ruminant livestock. Here, we describe a novel SBV subunit vac
Externí odkaz:
https://doaj.org/article/e1a0a7a06f3441369256cd76cabebf70
Autor:
Isaac Santos-Pérez, Diego Charro, David Gil-Carton, Mikel Azkargorta, Felix Elortza, Dennis H. Bamford, Hanna M. Oksanen, Nicola G. A. Abrescia
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Here, the authors present the cryo-EM structures of two archaeal, halophilic, internal membrane-containing icosahedral viruses at 3.7 and 3.8 Å resolution, providing insights into the assembly process of these and related PRD1-adeno lineage viruses.
Externí odkaz:
https://doaj.org/article/0446ee23b0d941e5a718dc70e9e5034b
Autor:
Sara Bertuzzi, Ana Gimeno, Ane Martinez-Castillo, Marta G. Lete, Sandra Delgado, Cristina Airoldi, Marina Rodrigues Tavares, Markéta Bláhová, Petr Chytil, Vladimír Křen, Nicola G. A. Abrescia, Ana Ardá, Pavla Bojarová, Jesús Jiménez-Barbero
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 11, p 6000 (2021)
The interaction of multi-LacNAc (Galβ1-4GlcNAc)-containing N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers with human galectin-1 (Gal-1) and the carbohydrate recognition domain (CRD) of human galectin-3 (Gal-3) was analyzed using NMR methods in
Externí odkaz:
https://doaj.org/article/0e97401a1d69496786418cab96a3933f
Autor:
Abhay Kotecha, Quan Wang, Xianchi Dong, Serban L. Ilca, Marina Ondiviela, Rao Zihe, Julian Seago, Bryan Charleston, Elizabeth E. Fry, Nicola G. A. Abrescia, Timothy A. Springer, Juha T. Huiskonen, David I. Stuart
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Foot-and-mouth disease virus binds αvβ6 integrin, via a conserved RGD motif in the flexible, exposed GH loop of capsid protein VP1, for cell entry. Here Kotechaet al.visualize this interaction with the VP1 GH loop extending away from the viral surf
Externí odkaz:
https://doaj.org/article/7cc85a0a325f47d7981c002ee69ab865
Autor:
Jiangyu Yan, Thomas R. Beattie, Adriana L. Rojas, Kelly Schermerhorn, Tamzin Gristwood, Jonathan C. Trinidad, Sonja V. Albers, Pietro Roversi, Andrew F. Gardner, Nicola G. A. Abrescia, Stephen D. Bell
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The current model for B-family DNA polymerases in archaea is one of single-subunit enzymes in contrast to the multi-subunit complexes in eukaryotes. Here the authors show that PolB1 fromSulfolobus solfataricusexists as a heterotrimeric complex in cel
Externí odkaz:
https://doaj.org/article/627c7d9ffa8c4d6aa1b8ab4ad90d0baa