Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Nicola De Maio"'
Autor:
Anna Basile, Valentina Giudice, Laura Mettivier, Antonia Falco, Anna Lisa Cammarota, Angela D’Ardia, Carmine Selleri, Margot De Marco, Nicola De Maio, Maria Caterina Turco, Liberato Marzullo, Alessandra Rosati
Publikováno v:
Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract The Bcl2-associated athanogene-3 (BAG3) protein, a critical regulator of cellular survival, has been identified as a potential therapeutic target in various malignancies. This study investigates the role of BAG3 within stromal fibroblasts an
Externí odkaz:
https://doaj.org/article/781eb40488154d1d9d949f60a66c1134
Autor:
Vladimir Shchur, Vadim Spirin, Dmitry Sirotkin, Evgeni Burovski, Nicola De Maio, Russell Corbett-Detig
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 8, p e1010409 (2022)
Accurate simulation of complex biological processes is an essential component of developing and validating new technologies and inference approaches. As an effort to help contain the COVID-19 pandemic, large numbers of SARS-CoV-2 genomes have been se
Externí odkaz:
https://doaj.org/article/d2e2aba4038b49308cabeffce68ef010
Autor:
Nicola De Maio, Alexander V. Alekseyenko, William J. Coleman-Smith, Fabio Pardi, Marc A. Suchard, Asif U. Tamuri, Jakub Truszkowski, Nick Goldman
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-24 (2021)
Abstract Background Many important applications in bioinformatics, including sequence alignment and protein family profiling, employ sequence weighting schemes to mitigate the effects of non-independence of homologous sequences and under- or over-rep
Externí odkaz:
https://doaj.org/article/800e81744aa5473185abd18a8a0160c6
Autor:
Nicola De Maio, William Boulton, Lukas Weilguny, Conor R Walker, Yatish Turakhia, Russell Corbett-Detig, Nick Goldman
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 4, p e1010056 (2022)
Sequence simulators are fundamental tools in bioinformatics, as they allow us to test data processing and inference tools, and are an essential component of some inference methods. The ongoing surge in available sequence data is however testing the l
Externí odkaz:
https://doaj.org/article/6d5c8fc4c57b436880fe75ca8bd66ce6
Autor:
H. Soon Gweon, Liam P. Shaw, Jeremy Swann, Nicola De Maio, Manal AbuOun, Rene Niehus, Alasdair T. M. Hubbard, Mike J. Bowes, Mark J. Bailey, Tim E. A. Peto, Sarah J. Hoosdally, A. Sarah Walker, Robert P. Sebra, Derrick W. Crook, Muna F. Anjum, Daniel S. Read, Nicole Stoesser, on behalf of the REHAB consortium
Publikováno v:
Environmental Microbiome, Vol 14, Iss 1, Pp 1-15 (2019)
Abstract Background Shotgun metagenomics is increasingly used to characterise microbial communities, particularly for the investigation of antimicrobial resistance (AMR) in different animal and environmental contexts. There are many different approac
Externí odkaz:
https://doaj.org/article/0d44895d887e4f3a9d6d056e7219808b
Autor:
Andrew Stewardson, Allen C Cheng, Tim Spelman, Sarah N Hilmer, Allen Cheng, Sarah Hilmer, Terry Haines, Trisha Peel, Anton Peleg, Natali Jokanovic, Rhonda L Stuart, Daniel Wilson, Kathryn E Holt, Yun-Hee Jeon, Andrew J Stewardson, Trisha N Peel, Anton Y Peleg, Kathryn Holt, Rhonda Stuart, Sue Lee, Annette Schmiede, James Trauer, Marilyn Cruickshank, Nicola De Maio, Bupa Aged Care
Publikováno v:
BMJ Open, Vol 11, Iss 3 (2021)
Introduction Antimicrobial resistance is a growing global health threat, driven by increasing inappropriate use of antimicrobials. High prevalence of unnecessary use of antimicrobials in residential aged care facilities (RACFs) has driven demand for
Externí odkaz:
https://doaj.org/article/54d9a5cc34224e48b57fc588d34942e9
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009221 (2021)
Many complex genomic rearrangements arise through template switch errors, which occur in DNA replication when there is a transient polymerase switch to an alternate template nearby in three-dimensional space. While typically investigated at kilobase-
Externí odkaz:
https://doaj.org/article/078472b6f95643dda24d866afb125955
Autor:
Antanas Kalkauskas, Umberto Perron, Yuxuan Sun, Nick Goldman, Guy Baele, Stephane Guindon, Nicola De Maio
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 1, p e1008561 (2021)
Phylogeographic inference allows reconstruction of past geographical spread of pathogens or living organisms by integrating genetic and geographic data. A popular model in continuous phylogeography-with location data provided in the form of latitude
Externí odkaz:
https://doaj.org/article/0c06b180312d4dc6810be855b1b5d574
Autor:
Yatish Turakhia, Nicola De Maio, Bryan Thornlow, Landen Gozashti, Robert Lanfear, Conor R Walker, Angie S Hinrichs, Jason D Fernandes, Rui Borges, Greg Slodkowicz, Lukas Weilguny, David Haussler, Nick Goldman, Russell Corbett-Detig
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009175 (2020)
The SARS-CoV-2 pandemic has led to unprecedented, nearly real-time genetic tracing due to the rapid community sequencing response. Researchers immediately leveraged these data to infer the evolutionary relationships among viral samples and to study k
Externí odkaz:
https://doaj.org/article/20e8f63f79c144ba9949393687772d59
Autor:
Joseph Crispell, Clare H Benton, Daniel Balaz, Nicola De Maio, Assel Ahkmetova, Adrian Allen, Roman Biek, Eleanor L Presho, James Dale, Glyn Hewinson, Samantha J Lycett, Javier Nunez-Garcia, Robin A Skuce, Hannah Trewby, Daniel J Wilson, Ruth N Zadoks, Richard J Delahay, Rowland Raymond Kao
Publikováno v:
eLife, Vol 8 (2019)
Quantifying pathogen transmission in multi-host systems is difficult, as exemplified in bovine tuberculosis (bTB) systems, but is crucial for control. The agent of bTB, Mycobacterium bovis, persists in cattle populations worldwide, often where potent
Externí odkaz:
https://doaj.org/article/47223c24eb2644b1819f6375e4835e0a