Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicola D. Collie"'
Publikováno v:
Nitric Oxide. 87:60-72
Nitric oxide (NO) produced by endothelial NO synthase (eNOS) is a key regulator of cerebral blood flow (CBF) dynamics. Mice with eNOS deficiency (eNOS-/-) display age-related increases in amyloid beta in the brain and memory deficits, implicating eNO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7e1e84a209434db48067917f204774d
https://doi.org/10.1016/j.niox.2019.03.006
https://doi.org/10.1016/j.niox.2019.03.006
Autor:
Daryl O. Schwenke, Philip Davis, Misa Yoshimoto, Tadakatsu Inagaki, Gerard T. Wilkins, Peter P. Jones, Keiji Umetani, Mikiyasu Shirai, James T. Pearson, Regis R. Lamberts, Nicola D. Collie
Publikováno v:
Endocrinology. 159:1763-1773
Acute myocardial infarction (MI) triggers an adverse increase in cardiac sympathetic nerve activity (SNA). Whereas β-adrenergic receptor (β-AR) blockers are routinely used for the management of MI, they may also counter β-AR-mediated vasodilation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd6de4e9d6dde4a010db57a7d8f00b5e
https://doi.org/10.1210/en.2017-03070
https://doi.org/10.1210/en.2017-03070
Publikováno v:
Neuroscience. 348:273-287
Some studies have demonstrated that aging is associated with impaired vestibular reflexes, especially otolithic reflexes, resulting in postural instability. However, the neurochemical basis of these age-related changes is still poorly understood. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56718c9e4f4455ae9147ccee134c7b1
https://doi.org/10.1016/j.neuroscience.2017.02.033
https://doi.org/10.1016/j.neuroscience.2017.02.033
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eff3439d14fad1b488aaa575c7451cd
https://doi.org/10.1016/j.jalz.2018.06.2464
https://doi.org/10.1016/j.jalz.2018.06.2464
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cdef80402ab8cfb7204507775cf75ce0
https://doi.org/10.1016/j.jalz.2018.06.1563
https://doi.org/10.1016/j.jalz.2018.06.1563
Publikováno v:
Neuropharmacology. 81:195-205
Phencyclidine (PCP), a non-competitive N-methyl-d-aspartate glutamate receptor antagonist, induces schizophrenic symptoms in healthy individuals, and altered arginine metabolism has been implicated in schizophrenia. The present study investigated the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::726d21f3e4a97b3c734da1f58958b441
https://doi.org/10.1016/j.neuropharm.2014.02.004
https://doi.org/10.1016/j.neuropharm.2014.02.004
Publikováno v:
Translational Psychiatry
Previous research implicates altered metabolism of l-arginine, a versatile amino acid with a number of bioactive metabolites, in the pathogenesis of schizophrenia. The present study, for we believe the first time, systematically compared the metaboli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85733dfa1c6652fde976c9e7c3304ec3
https://pubmed.ncbi.nlm.nih.gov/27529679
https://pubmed.ncbi.nlm.nih.gov/27529679
Publikováno v:
Neuroscience. 226:178-196
A growing body of evidence suggests the involvement of L-arginine and its metabolites in the ageing and neurodegenerative processes. The present study assessed behavioural performance in 4- (young), 12- (middle-aged) and 24- (aged) month-old male Spr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5811a57619e3f39f322b174a85ca7246
https://doi.org/10.1016/j.neuroscience.2012.09.013
https://doi.org/10.1016/j.neuroscience.2012.09.013
Autor:
Joanna M. Williams, Nicola D. Collie, Ping Liu, Jeremy T. T. Kennard, M. Rushaidhi, Yu Jing, Hu Zhang
Publikováno v:
Neuroscience. 209:21-31
L-arginine, one of the most metabolically versatile amino acids, can be metabolized to form a number of bioactive molecules. The present study systematically investigated age-related changes in L-arginine and its metabolites in the hippocampus, parah
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::979b8ebd9488d40d78e080f7cf9cf579
https://doi.org/10.1016/j.neuroscience.2012.02.021
https://doi.org/10.1016/j.neuroscience.2012.02.021
Publikováno v:
Neuropharmacology. 61:1452-1462
Alzheimer's disease (AD) is a neurodegenerative disorder with progressive memory loss. It has been shown that the cholinergic neurotransmission deficit is one of the neurochemical characteristics of AD, and that L-arginine and its metabolites also pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25fbaac4abb92a3e027d9faf22b6e642
https://doi.org/10.1016/j.neuropharm.2011.08.042
https://doi.org/10.1016/j.neuropharm.2011.08.042