Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Nicola Calonaci"'
Autor:
Alice Antonello, Riccardo Bergamin, Nicola Calonaci, Jacob Househam, Salvatore Milite, Marc J. Williams, Fabio Anselmi, Alberto d’Onofrio, Vasavi Sundaram, Alona Sosinsky, William C. H. Cross, Giulio Caravagna
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-40 (2024)
Abstract Copy number alterations (CNAs) are among the most important genetic events in cancer, but their detection from sequencing data is challenging because of unknown sample purity, tumor ploidy, and general intra-tumor heterogeneity. Here, we pre
Externí odkaz:
https://doaj.org/article/58afabce18a849ecb410852f49a33e9f
Autor:
Lucrezia Patruno, Salvatore Milite, Riccardo Bergamin, Nicola Calonaci, Alberto D'Onofrio, Fabio Anselmi, Marco Antoniotti, Alex Graudenzi, Giulio Caravagna
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 11, p e1011557 (2023)
Single-cell RNA and ATAC sequencing technologies enable the examination of gene expression and chromatin accessibility in individual cells, providing insights into cellular phenotypes. In cancer research, it is important to consistently analyze these
Externí odkaz:
https://doaj.org/article/711143dbbcf84508bb43f4555ba5999a
Autor:
Erika Tissino, Nicola Calonaci, Federico Pozzo, Filippo Vit, Annalisa Gaglio, Lodovico Terzi DI Bergamo, Tamara Bittolo, Francesca Maria Rossi, Robel Papotti, Ilaria Catarossi, Eva Zaina, Paola Nanni, Riccardo Bergamin, Leonardo Egidi, Giovanni Santacatterina, Salvatore Milite, Maria Ilaria Del Principe, Roberta Laureana, Jacopo Olivieri, Francesco Zaja, Annalisa Chiarenza, Davide Rossi, Riccardo Bomben, Valter Gattei, Antonella Zucchetto, Giulio Caravagna
Publikováno v:
HemaSphere, Vol 7, p e7042158 (2023)
Externí odkaz:
https://doaj.org/article/73e887b6f43d4d0188730e751f7b5a07
Autor:
Erika Tissino, Nicola Calonaci, Federico Pozzo, Gabriela Forestieri, Lodovico Terzi Di Bergamo, Filippo Vit, Annalisa Gaglio, Riccardo Bergamin, Salvatore Milite, Stefano Cozzini, Maria Ilaria Del Principe, Roberta Laureana, Annalisa Chiarenza, Jacopo Olivieri, Francesco Zaja, Cristoforo Fabbris, Valentina Lupato, Riccardo Bomben, Davide Rossi, Valter Gattei, Antonella Zucchetto, Giulio Caravagna
Publikováno v:
Blood. 140:9844-9846
Computational validation of clonal and subclonal copy number alterations from bulk tumour sequencing
Autor:
Alice Antonello, Riccardo Bergamin, Nicola Calonaci, Jacob Househam, Salvatore Milite, Marc J Williams, Fabio Anselmi, Alberto d’Onofrio, Vasavi Sundaram, Alona Sosinsky, William CH Cross, Giulio Caravagna
Cancer is a global health issue that places enormous demands on healthcare systems. Basic research, the development of targeted treatments, and the utility of DNA sequencing in clinical settings, have been significantly improved with the introduction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90bf93d9fcbccdf1f2ea0af71003300a
https://doi.org/10.1101/2021.02.13.429885
https://doi.org/10.1101/2021.02.13.429885
MotivationCancers are composed by several heterogeneous subpopulations, each one harbouring different genetic and epigenetic somatic alterations that contribute to disease onset and therapy response. In recent years, copy number alterations leading t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7236e1d5fc1d331a4101d7919ede05e
https://doi.org/10.1101/2021.02.02.429335
https://doi.org/10.1101/2021.02.02.429335
Publikováno v:
The Journal of chemical physics. 152(23)
Biomolecular force fields have been traditionally derived based on a mixture of reference quantum chemistry data and experimental information obtained on small fragments. However, the possibility to run extensive molecular dynamics simulations on lar
Publikováno v:
NAR Gen. Bioinfo. 2:lqaa090 (2020)
NAR Genomics and Bioinformatics
NAR Genomics and Bioinformatics
RNA function crucially depends on its structure. Thermodynamic models currently used for secondary structure prediction rely on computing the partition function of folding ensembles, and can thus estimate minimum free-energy structures and ensemble p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669643d56a5b189a0865c0cfb15e00c9
http://arxiv.org/abs/2004.00351
http://arxiv.org/abs/2004.00351
Publikováno v:
Journal of Polymer Science Part B: Polymer Physics. 55:1760-1769
The relation between elasticity and yielding is investigated in a model polymer solid by Molecular-Dynamics simulations. By changing the bending stiffness of the chain and the bond length, semicrystalline and disordered glassy polymers - both with bo