Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Nicola Cacciani"'
Autor:
Young il Lee, Nicola Cacciani, Ya Wen, Xiang Zhang, Yvette Hedström, Wesley Thompson, Lars Larsson
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 3, Pp 1533-1545 (2023)
Abstract Background There is increasing evidence of crosstalk between organs. The neuromuscular junction (NMJ) is a peripheral chemical synapse whose function and morphology are sensitive to acetylcholine (ACh) release and muscle depolarization. In a
Externí odkaz:
https://doaj.org/article/d6001089fb6a44d6b3d587ae4c277905
Autor:
Nicola Cacciani, Åsa Skärlén, Ya Wen, Xiang Zhang, Alex B. Addinsall, Monica Llano‐Diez, Meishan Li, Lennart Gransberg, Yvette Hedström, Bo‐Michael Bellander, David Nelson, Jonas Bergquist, Lars Larsson
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 6, Pp 2669-2682 (2022)
Abstract Background Critical illness myopathy (CIM) is a consequence of modern critical care resulting in general muscle wasting and paralyses of all limb and trunk muscles, resulting in prolonged weaning from the ventilator, intensive care unit (ICU
Externí odkaz:
https://doaj.org/article/f263affcb0e94e709d6974452f755330
Autor:
Sofia Mnuskina, Julian Bauer, Anette Wirth-Hücking, Dominik Schneidereit, Stefanie Nübler, Paul Ritter, Nicola Cacciani, Meishan Li, Lars Larsson, Oliver Friedrich
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Ventilator-induced diaphragm dysfunction (VIDD) is a common sequela of intensive care unit (ICU) treatment requiring mechanical ventilation (MV) and neuromuscular blockade (NMBA). It is characterised by diaphragm weakness, prolonged respirator weanin
Externí odkaz:
https://doaj.org/article/79d709fcaf8a49d58bdb610651053aaf
Autor:
Alex B. Addinsall, Nicola Cacciani, Anders Backéus, Yvette Hedström, Ganna Shevchenko, Jonas Bergquist, Lars Larsson
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 4, Pp 2162-2174 (2022)
Abstract Background Critical illness myopathy (CIM) is a debilitating condition characterized by the preferential loss of the motor protein myosin. CIM is a by‐product of critical care, attributed to impaired recovery, long‐term complications, an
Externí odkaz:
https://doaj.org/article/6352fc59ec1347d78ae38dcf6920c608
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Background Old age is associated with a significantly increased mortality in COVID-19 patients exposed to long-term controlled mechanical ventilation (CMV) and suggested to be due to the hyperinflammatory response associated with the viral i
Externí odkaz:
https://doaj.org/article/ac24b85a07de42dca70861ea742e249a
Maintenance of sarcomeric integrity in adult muscle cells crucially depends on Z-disc anchored titin
Autor:
Sandra Swist, Andreas Unger, Yong Li, Anja Vöge, Marion von Frieling-Salewsky, Åsa Skärlén, Nicola Cacciani, Thomas Braun, Lars Larsson, Wolfgang A. Linke
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Titin is considered an integrator of muscle cell proteins but direct evidence is limited. Here, titin is inactivated in adult mouse muscles, which causes sarcomere disassembly, protein mis-expression and force impairment, recapitulating key alteratio
Externí odkaz:
https://doaj.org/article/302edbcae576463d8910dcb3be630c60
Publikováno v:
Frontiers in Physiology, Vol 7 (2016)
Intensive care unit (ICU) patients are often overtly subjected to mechanical ventilation and immobilization, which leads to impaired limb and respiratory muscle function. The latter, termed ventilator-induced diaphragm dysfunction (VIDD) has recently
Externí odkaz:
https://doaj.org/article/7cb10e86cc6d4c289f5404f7347cbdde
Publikováno v:
Journal of Orthopaedic Research. 40:1293-1300
Prolonged mechanical ventilation for critically-ill patients with respiratory distress can result in severe muscle wasting with preferential loss of myosin. Systemic inflammation triggered by lung mechanical injury likely contributes to this myopathy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da361007f0294b8831158bf9f305631
https://doi.org/10.1002/jor.25161
https://doi.org/10.1002/jor.25161
Publikováno v:
Skeletal Muscle, Vol 11, Iss 1, Pp 1-12 (2021)
Skeletal Muscle
Skeletal Muscle
Background Old age is associated with a significantly increased mortality in COVID-19 patients exposed to long-term controlled mechanical ventilation (CMV) and suggested to be due to the hyperinflammatory response associated with the viral infection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa0104123da97b1c7c8a1404d2605da
https://doaj.org/article/ac24b85a07de42dca70861ea742e249a
https://doaj.org/article/ac24b85a07de42dca70861ea742e249a
Autor:
Alex B. Addinsall, Nicola Cacciani, Hasem Akkad, Noah Moruzzi, Alice Maestri, Ganna Shevchenko, Jonas Bergquist, Jorge Ruas, Lars Larsson
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a61767789b765aa268372bd6915e3e85
https://doi.org/10.1096/fasebj.2022.36.s1.r3357
https://doi.org/10.1096/fasebj.2022.36.s1.r3357