Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Nicola C. Reading"'
Autor:
David Alvarez, Dennis L. Kasper, Ulrich H. von Andrian, Jason E. Hudak, Deniz Erturk-Hasdemir, Naama Geva-Zatorsky, Suryasarathi Dasgupta, Nicola C. Reading
Publikováno v:
Nature Medicine. 21:1091-1100
The intestine is densely populated by anaerobic commensal bacteria. These microorganisms shape immune system development, but understanding of host-commensal interactions is hampered by a lack of tools for studying the anaerobic intestinal environmen
Autor:
Jason E. Hudak, Dennis L. Kasper, Naama Geva-Zatorsky, Suryasarathi Dasgupta, Ulrich H. von Andrian, David Alvarez, Deniz Erturk-Hasdemir, Nicola C. Reading Mans
Publikováno v:
Cancer Immunology Research. 4:IA18-IA18
Adaptive co-evolution has formed a complex network of inextricable bonds between the resident microbes and the mammalian host. These symbiotic microbes are now believed to have critical impacts on human health. One of the most common gut symbionts, B
Autor:
Eduardo J. Villablanca, Diane Mathis, Yoshinori Umesaki, Nicola C. Reading, Sean-Jiun Wang, Sünje Johanna Pamp, Erin B. Troy, Christophe Benoist, Hachung Chung, David A. Relman, Neeraj K. Surana, J R Mora, Sanna M. Edelman, Jonathan A. Hill, Dennis L. Kasper
Publikováno v:
Cell. 149(7)
SummaryGut microbial induction of host immune maturation exemplifies host-microbe mutualism. We colonized germ-free (GF) mice with mouse microbiota (MMb) or human microbiota (HMb) to determine whether small intestinal immune maturation depends on a c
Autor:
Nicola C. Reading, Dennis L. Kasper
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 2 (2011)
Frontiers in Microbiology
Frontiers in Microbiology
The complexity of microbiota inhabiting the intestine is increasingly apparent. Delicate balance of numerous bacterial species can affect development of the immune system, how susceptible a host is to pathogenic organisms, and the auto-inflammatory s
Publikováno v:
Microbiology (Reading, England). 156(Pt 4)
QseE is a sensor kinase that responds to epinephrine, sulfate and phosphate. QseE constitutes a two-component signalling system together with the QseF σ 54-dependent response regulator. Encoded within the same operon as qseEF is the qseG gene, which
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(14)
Bacterial pathogens sense host cues to activate expression of virulence genes. Most of these signals are sensed through histidine kinases (HKs), which comprise the main sensory mechanism in bacteria. The host stress hormones epinephrine (Epi) and nor
Autor:
Shuguang Wei, Ronald Taussig, David A. Rasko, Cristiano G. Moreira, Matthew K. Waldor, De Run Li, David Hughes, Jason F. Huntley, Michael G. Roth, Noelle S. Williams, Jennifer M. Ritchie, Vanessa Sperandio, John R. Falck, Maggy Fina, Nicola C. Reading
Publikováno v:
Science (New York, N.Y.). 321(5892)
Many bacterial pathogens rely on a conserved membrane histidine sensor kinase, QseC, to respond to host adrenergic signaling molecules and bacterial signals in order to promote the expression of virulence factors. Using a high-throughput screen, we i
Autor:
Vanessa Sperandio, Kaneyoshi Yamamoto, Melissa M. Kendall, Alfredo G. Torres, David Hughes, Nicola C. Reading
Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is responsible for worldwide outbreaks of bloody diarrhea, hemorrhagic colitis, and life-threatening hemolytic uremic syndrome. After colonizing the large intestine, EHEC forms attaching and effacing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dda251c974a8a0b3d8f88e6775138884
https://europepmc.org/articles/PMC1899401/
https://europepmc.org/articles/PMC1899401/
Autor:
Nicola C. Reading, Vanessa Sperandio
Publikováno v:
FEMS microbiology letters. 254(1)
In the conventional view of prokaryotic existence, bacteria live unicellularly, with responses to external stimuli limited to the detection of chemical and physical signals of environmental origin. This view of bacteriology is now recognized to be ov
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